1. Editorial

   Editorial Introduction Pages: 1 - 2

2. Profuse familial adenomatous polyposis with an Adenomatous Polyposis Coli exon 3 mutation

   • Steven Nasioulas
   • Ian T. Jones
   • R. J. McKinlay Gardner

   OriginalPaper Pages: 3 - 7

3. Genotype and phenotype in hereditary nonpolyposis colon cancer: a study of families with different vs. shared predisposing mutations

   • Päivi Peltomäki
   • Xin Gao
   • Jukka-Pekka Mecklin

   OriginalPaper Pages: 9 - 15

4. Double primary cancers of the breast and thyroid in women: molecular analysis and genetic implications

   • Tuya Pal
   • Nancy Hamel
   • Steven A. Narod

   OriginalPaper Pages: 17 - 24

5. A paradox: urgent BRCA genetic testing

   • G. Mitchell
   • A. Ardern-Jones
   • R. A. Eeles

   OriginalPaper Pages: 25 - 29

6. Women at risk of ovarian cancer: attitudes towards and expectations of the familial ovarian cancer clinic

   • Ruth Sheppard
   • Alison Fry
   • Ann Cull

   OriginalPaper Pages: 31 - 37

7. Cytogenetic characteristics of oral squamous cell carcinomas in Fanconi anemia

   • Mario A. J. A. Hermsen
   • Yan Xie
   • Hans Joenje

   OriginalPaper Pages: 39 - 43

8. Population-based study of familial medullary thyroid cancer

   • Kari Hemminki
   • Chuanhui Dong

   OriginalPaper Pages: 45 - 49

9. Familial cancer database: a clinical aide-mémoire

   • Rolf H. Sijmons
   • Gerard T. N. Burger

   OriginalPaper Pages: 51 - 55

10. Cancer risk in mismatch repair gene mutation carriers

    • Patrice Watson
    • Henry T. Lynch

    ReviewPaper Pages: 57 - 60

11. Instructions for authors

    Instructions for Authors Pages: 61 - 64