1. Foreword: Why Study Nuclear Architecture?

   Foreword Pages: 385 - 386

2. The principles of nuclear structure

   • Dean A. Jackson

   OriginalPaper Pages: 387 - 401

3. Is DNA sequence sufficient to specify DNA replication origins in metazoan cells?

   • Giuseppe Biamonti
   • Sónia Paixão
   • Arturo Falaschi

   OriginalPaper Pages: 403 - 412

4. Exploiting a minimal system to study the epigenetic control of DNA replication: the interplay between transcription and replication

   • Isa M. Stehle
   • Monica F. Scinteie
   • Hans J. Lipps

   OriginalPaper Pages: 413 - 421

5. Chromatin folding and gene expression: new tools to reveal the spatial organization of genes

   • Karen E. Brown

   OriginalPaper Pages: 423 - 433

6. From DNA structure to gene expression: mediators of nuclear compartmentalization and dynamics

   • J. Bode
   • S. Goetze
   • C. Benham

   OriginalPaper Pages: 435 - 445

7. Spatial organization of gene expression: the active chromatin hub

   • Wouter de Laat
   • Frank Grosveld

   OriginalPaper Pages: 447 - 459

8. Transcription factories: quantitative studies of nanostructures in the mammalian nucleus

   • Sonya Martin
   • Ana Pombo

   OriginalPaper Pages: 461 - 470

9. Comparative analysis of the functional genome architecture of animal andplant cell nuclei

   • Christoph Mayr
   • Zuzana Jasencakova
   • Daniele Zink

   OriginalPaper Pages: 471 - 484

10. Three-dimensional arrangements of centromeres and telomeres in nuclei of human and murine lymphocytes

    • Claudia Weierich
    • Alessandro Brero
    • Irina Solovei

    OriginalPaper Pages: 485 - 502

11. Conservation of chromosome arrangement and position of the X in mammalian sperm suggests functional significance

    • Ian K. Greaves
    • Willem Rens
    • Jennifer A. Marshall Graves

    OriginalPaper Pages: 503 - 512

12. A genetic analysis of chromosome territory looping: diverse roles for distal regulatory elements

    • Tobias Ragoczy
    • Agnes Telling
    • Steven T. Kosak

    OriginalPaper Pages: 513 - 525

13. Nuclear microenvironments support physiological control of gene expression

    • Gary S. Stein
    • Jane B. Lian
    • Shirwin Pockwinse

    OriginalPaper Pages: 527 - 536

14. Four-dimensional imaging of chromatin dynamics during the assembly of the interphase nucleus

    • E. M. M. Manders
    • A. E. Visser
    • R. van Driel

    OriginalPaper Pages: 537 - 547