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Risk factors for basal cell carcinoma: Results from the case-control study

  • Research Article
  • Published:
Central European Journal of Medicine

Abstract

The aim of the present case-control study was to assess the risk factors for Basal cell carcinoma (BCC) in the Montenegrin population. The study group was comprised of 100 consecutive patients with a diagnosis of BCC, while the control group consisted of patients who did not present skin cancer and who were individually matched to the cases by sex and age. The increased risk for BCC was associated with: the presence of nevi (odds ratio [OR] = 3.77; 95% confidence interval [CI] = 1.12–12.73), type of skin concerning to burn rather than to tan after repeated sun exposure in childhood or adolescence (OR = 3.14; 95% CI = 1.59–6.18), the skin reaction to burn after two or more hours of sunlight during childhood or adolescence (OR = 4.53; 95% CI = 2.37–8.63), the number of severe and painful sunburns during their lifetime(OR = 3.52; 95% CI = 1.68–7.38), outdoor work during the summer-time (OR = 2.73; 95% CI = 1.00–7.45), occupational exposure to chemicals (OR = 17.89; 95% CI = 2.82–113.52), history of eczema (OR = 4.17; 95% CI = 1.53–11.39), and history of previous BCC (OR = 3.86; 95% CI = 1.40–10.65). Our study confirms the role of environmental and constitutional factors in development of BCC.

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Authors and Affiliations

  1. Institute of Epidemiology, School of Medicine, University of Belgrade, Višegradska 26, 11000, Belgrade, Serbia

    Slavenka Janković & Nataša Maksimović

  2. Institute of Social Medicine, School of Medicine, University of Belgrade, 11000, Belgrade, Serbia

    Janko Janković

  3. Department of Dermatology and Venereology, Clinical Center of Montenegro, 81000, Podgorica, Montenegro

    Milena Ražnatović

  4. Institute of Medical Statistics and Informatics, School of Medicine, University of Belgrade, 11000, Belgrade, Serbia

    Jelena Marinković

  5. Institute of Allergology and Immunology, Clinical Center of Serbia, 11000, Belgrade, Serbia

    Vesna Tomić-Spirić

Authors
  1. Slavenka Janković
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  2. Nataša Maksimović
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  3. Janko Janković
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  4. Milena Ražnatović
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  6. Vesna Tomić-Spirić
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Correspondence to Slavenka Janković.

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Janković, S., Maksimović, N., Janković, J. et al. Risk factors for basal cell carcinoma: Results from the case-control study. cent.eur.j.med 5, 666–673 (2010). https://doi.org/10.2478/s11536-010-0042-5

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  • DOI: https://doi.org/10.2478/s11536-010-0042-5

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