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Severe aplastic anemia in a patient with rheumatoid arthritis after introduction of etanercept

  • Case Report
  • Published:
Central European Journal of Medicine

Abstract

A 73-year-old female, diagnosed with rheumatoid arthritis (RA), complicated with severe levels of joint destruction, started etanercept (ETN) because of high persistent RA disease activity. Although her articular symptoms dramatically improved, she developed marked pancytopenia after the introduction of ETN. Bone marrow aspirate specimen revealed hypocellular marrow in three hematopoietic series without atypical findings, which was compatible with aplastic anemia (AA). This is a rare case of severe pancytopenia due to AA presumably induced by ETN.

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Authors and Affiliations

  1. Department of Internal Medicine and Rheumatology, Clinical Research Center, National Hospital, Organization Kyushu Medical Center, 1-8-1 Jigyohama Chuo-ku, Fukuoka, 810-8563, Japan

    Yoshiro Horai, Tomoya Miyamura, Karin Shimada, Motoko Ishida, Soichiro Takahama, Rumi Minami, Masahiro Yamamoto & Eiichi Suematsu

Authors
  1. Yoshiro Horai
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  2. Tomoya Miyamura
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  3. Karin Shimada
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  4. Motoko Ishida
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  5. Soichiro Takahama
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  6. Rumi Minami
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  7. Masahiro Yamamoto
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  8. Eiichi Suematsu
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Correspondence to Yoshiro Horai.

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Horai, Y., Miyamura, T., Shimada, K. et al. Severe aplastic anemia in a patient with rheumatoid arthritis after introduction of etanercept. cent.eur.j.med 7, 650–654 (2012). https://doi.org/10.2478/s11536-012-0037-5

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  • DOI: https://doi.org/10.2478/s11536-012-0037-5

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