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Non-palpable and non-invasive ductal carcinoma with bloody nipple discharge successfully resected after cancer spread was accurately diagnosed with three-dimensional computed tomography and galactography

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Abstract

A case of ductal carcinomain situ (DCIS) that was treated by partial mastectomy is reported. The operation was performed after accurate estimation of cancer spread by three-dimensional computed tomography (3D-CT). The patient was a 39-year-old woman without a palpable lump who had a bloody nip-ple discharge. Ultrasonography showed distended mammary ducts with intraductal components. Fine needle aspiration cytology revealed ductal carcinoma. Galactography showed two subsegmental ducts and peripheral branches in the upper-inner quadrant of the right breast. 3D-CT depicted a well enhanced segmental-clumped lesion including two subsegments of a duct lobular system shown in galactograms. DCIS was diagnosed and partial mastectomy following the video assisted thoracoscopic surgery (VATS) marker insertion was performed, after cancer spread was accurately diagnosed by 3D-CT guidance. DCIS resected by minimally sufficient partial mastectomy with negative surgical margins was diagnosed histopathologically.

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Abbreviations

CT:

Computed tomography

DCIS:

Ductal carcinomain situ

MR:

Magnetic resonance

VATS:

Video assisted thoracoscopic surgery

3D-CT:

Three-dimensional computed tomography

References

  1. Bauer RL, Eckhert KH Jr, Nemoto T: Ductal carcinoma in situassociated nipple discharge: a clinical marker for locally extensive disease.Ann Surg Oncol 5:452–455, 1998.

    Article  CAS  Google Scholar 

  2. Ohouchi N, Furuta A, Mori S: Management of ductal carcinoma in situ with nipple discharge.Cancer 74:1294–1302, 1994.

    Article  Google Scholar 

  3. Tabar L, Dean PB, Pentek Z: Galactography: the diagnostic procedure of choice of nipple discharge.Radiology 149:31–38, 1983.

    Article  CAS  Google Scholar 

  4. Satake H, Shimamoto K, Sawaki A, Niimi R, Ando Y, Ashibuchi T, Ishigaki T, Yamakawa K, Nagasaka T, Funahashi H: Role of ultrasonography in the detection of intraductal spread of breast cancer: correlation with pathologic findings, mammography and MR imaging.Eur Radiol 10:1726–1732, 2000.

    Article  CAS  Google Scholar 

  5. Uematsu T, Sano M, Homma K, Sato N: Value of three-dimensional helical CT image-guided planning for made-to-order lumpectomy in breast cancer patients.Breast J 10:33–37, 2004.

    Article  Google Scholar 

  6. Satake H, Shimamoto K, Itoh S, Sawaki A, Noguchi Y, Ishigaki T: Diagnosis of breast cancer by multislice CT.Nichidoku-Iho 46:133–141, 2001(in Japanese with English abstract).

    Google Scholar 

  7. Ito Y, Tamaki Y, Nakano Y, Kobayashi T, Takeda T, Wakasugi E, Miyashiro I, Komoike Y, Miyazaki M, Nakayama T, Kano T, Monden M: Nonpalpable breast cancer with nipple discharge: how should it be treated?Anticancer Res 17:269–280, 1997.

    Google Scholar 

  8. Silverstein MJ, Gierson ED, Colburn WJ, Cope LM, Furmanski M, Senofsky GM, Gamagami P, Waisman JR: Can intraductal breast carcinoma be excised completely by local excision?Cancer 73:2985–2989, 1994.

    Article  CAS  Google Scholar 

  9. Holland R, Hendricks JHCL, Verbeek ALM: Extent, distribution, and mammographic/histologic correlations of breast ductal carcinoma in situ.Lancet 335:519–522, 1990.

    Article  CAS  Google Scholar 

  10. Soo MS, Baker JA, Rosen EL: Sonographic detection and sonographically guided biopsy of breast micro-calcifications.AJR 180:941–948, 2003.

    Article  Google Scholar 

  11. Hou MF, Huaug TJ, Liu GC: The diagnostic value of galactography in patients with nipple discharge.Clin Imaging 25:75–81, 2001.

    Article  CAS  Google Scholar 

  12. Boetes C, Mus RDM, Holland R, Barentsz JO, Strijk SP, Wobbes T, Hendriks JHCL, Ruys SHJ: Breast tumors: comparative accuracy of MR imaging relative to mammography and US for demonstrating extent.Radiology 197:743–747, 1995.

    Article  CAS  Google Scholar 

  13. Uematsu T, Sano M, Homma K, Shiina M, Kobayashi S: Three-dimensional helical CT of the breast: accuracy for measuring extent of breast cancer candidates for breast conserving surgery.Breast Cancer Res Treat 65:249–257, 2001.

    Article  CAS  Google Scholar 

  14. Gills R, Zafrani B, Guinebretiere LM, Meunier M, Luci-darme O, Tardivon AA, Rochard F, Vanel D, Neuen-schwander S, Arriagada R: Ductal carcinoma in situ: MR imaging-histopathologic correlation.Radiology 196:415–419, 1995.

    Article  Google Scholar 

  15. Makino H, Sano M, Uematsu T, Honma K: Role of Image Diagnosis in Breast Conserving Surgery-Simulation of Surgery Using Helical CT.Jpn J Breast Cancer 13:447–453, 1998(in Japanese with English abstract).

    Google Scholar 

  16. Makita M, Gomi N, Tachikawa T, Iwase T, Takahashi K, Tada K, Nishimura S, Yoshimoto M, Akiyama F, Yamashita T, Kasumi F, Sakamoto G: CT-guided Thermoplastic assisted segmentectomy is an optimal breast conserving surgery for breast cancer with nipple discharge.Jpn J Breast Cancer 19:142–149, 2004(in Japanese with English abstract).

    Google Scholar 

  17. Choudhury A, Wengert PA, Smith S: A new surgical location technique for biopsy in patients with nipple discharge.Arch Surg 124:874–875, 1989.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Kato Surgery Gynecology Obstetrics Breast Clinic, Department of Surgery, Nagoya University Graduate School of Medicine, Japan

    Masamichi Kato

  2. Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Japan

    Koji Oda & Yuji Nimura

  3. Department of Surgery, Kamiiida Daiichi Hospital, Japan

    Tomoyuki Kubota & Makoto Kato

  4. Department of Radiology, Nagoya University Graduate School of Medicine, Japan

    Hiroko Satake

Authors
  1. Masamichi Kato
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  2. Koji Oda
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  3. Tomoyuki Kubota
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  4. Hiroko Satake
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  5. Makoto Kato
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  6. Yuji Nimura
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Correspondence to Masamichi Kato.

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Kato, M., Oda, K., Kubota, T. et al. Non-palpable and non-invasive ductal carcinoma with bloody nipple discharge successfully resected after cancer spread was accurately diagnosed with three-dimensional computed tomography and galactography. Breast Cancer 13, 360–363 (2006). https://doi.org/10.2325/jbcs.13.360

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  • DOI: https://doi.org/10.2325/jbcs.13.360

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