Skip to main content
Log in

Glucosamine improves symptoms of osteoarthritis, but further studies on its disease-modifying effects are needed

  • Drugs and Profile Report
  • Published:
Drugs & Therapy Perspectives Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Notes

  1. The use of trade names is for product identification purposes only and does not imply endorsement.

References

  1. Matheson AJ, Perry CM. Glucosamine: a review of its use in the management of osteoarthritis. Drugs Aging 2003; 20(14): 1041–60

    Article  PubMed  CAS  Google Scholar 

  2. Rotta Pharmaceuticals. Glucosamine sulfate: summary of product characteristics. Milan: Rotta Pharmaceuticals, 1999

    Google Scholar 

  3. Setnikar I, Palumbo R, Canali S, et al. Pharmacokinetics of glucosamine in man. Arzneimittelforschung 1993; 43(10): 1109–13

    PubMed  CAS  Google Scholar 

  4. Noack W, Fischer M, Förster KK, et al. Glucosamine sulfate in osteoarthritis of the knee. Osteoarthritis Cartilage 1994; 2(1): 51–9

    Article  PubMed  CAS  Google Scholar 

  5. Reichelt A, Förster KK, Fischer M, et al. Efficacy and safety of intramuscular glucosamine sulfate in osteoarthritis of the knee: a randomised, placebo-controlled, double-blind study. Arzneimittel Forschung 1994; 44(1): 75–80

    PubMed  CAS  Google Scholar 

  6. Giacovelli G, Rovati LC. Clinical efficacy of glucosamine sulfate in osteoarthritis of the spine [abstract no. Mo 96]. Rev Esp Reumatol 1993 Jul; 20 Suppl. 1: 325

    Google Scholar 

  7. Müller-Faßbender H, Bach GL, Haase W, et al. Glucosamine sulfate compared to ibuprofen in osteoarthritis of the knee. Osteoarthritis Cartilage 1994; 2: 61–9

    Article  PubMed  Google Scholar 

  8. Qiu GX, Gao SN, Giacovelli G, et al. Efficacy and safety of glucosamine sulfate versus ibuprofen in patients with knee osteoarthritis. Arzneimittel Forschung 1998 May; 48(5): 469–74

    PubMed  CAS  Google Scholar 

  9. Rovati LC. The clinical profile of glucosamine sulfate as a selective symptom modifying drug in osteoarthritis: current data and perspectives [abstract no. sym.20]. Osteoarthritis Cartilage 1997; 5: 72

    Google Scholar 

  10. Lopes-Vaz A. Double-blind clinical evaluation of the relative efficacy of ibuprofen and glucosamine sulphate in the management of osteoarthrosis of the knee in out-patients. Curr Med Res Opin 1982; 8(3): 145–9

    Article  PubMed  CAS  Google Scholar 

  11. Reginster JY, Deroisy R, Rovati LC, et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial. Lancet 2001 Jan 27; 357: 251–6

    Article  PubMed  CAS  Google Scholar 

  12. Pavelká K, Gatterová J, Olejarová M, et al. Glucosamine sulfate use and delay of progression of knee osteoarthritis: a 3-year, randomized, placebo-controlled, double-blind study. Arch Intern Med 2002 Oct 14; 162: 2113–23

    Article  PubMed  Google Scholar 

  13. Richy F, Bruyere O, Ethgen O, et al. Structural and symptomatic efficacy of glucosamine and chondroitin in knee osteoarthritis: a comprehensive meta-analysis. Arch Intern Med 2003 Jul 14; 163: 1514–22

    Article  PubMed  CAS  Google Scholar 

Download references

Rights and permissions

Reprints and permissions

About this article

Cite this article

Glucosamine improves symptoms of osteoarthritis, but further studies on its disease-modifying effects are needed. Drugs Ther. Perspect 20, 1–4 (2004). https://doi.org/10.2165/00042310-200420100-00001

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00042310-200420100-00001

Navigation