Summary
The effects of β-blockade on glucose metabolism are complex. Some patients with impaired glucose tolerance while taking a non-selectiveβ-blocker, showed some improvement in glucose tolerance when therapy was changed to a β1 -blocker (metoprolol). Serum K+ values tend to rise slightly on β-blocking therapy; small increases in serum urea and creatinine also occur. A rise in plasma triglycerides was noted in patients startingβ-blocking therapy; this effect seemed to be more marked on metoprolol than on non-selectiveβ-blockers.
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Waal-Manning, H.J. Metabolic Effects ofβ-Adrenoreceptor Blockers. Drugs 11 (Suppl 1), 121–126 (1976). https://doi.org/10.2165/00003495-197600111-00027
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DOI: https://doi.org/10.2165/00003495-197600111-00027