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Using Magnetic Resonance Imaging to Select and Manage Patients for Treatment

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Thrombolytic Therapy for Acute Stroke

Part of the book series: Current Clinical Neurology ((CCNEU))

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Abstract

Thrombolysis is the treatment of choice for eligible acute stroke within 3 h after symptom onset. However, in the United States, only 2–5% of acute stroke patients receive this therapy, and among those patients who are treated there remains a risk of developing a symptomatic intracerebral hemorrhage (ICH) (1–3). Moreover, no treatment beyond 3 h has been approved by regulatory agencies. Thus, there is an urgent need to optimize safety and efficacy of thrombolytic therapy in the early time window (<3 h from onset), and identify selection criteria for therapies that can be safely extended into later time windows. Multimodal neuroimaging techniques are now available in the clinical setting and may provide an opportunity to meet both these needs.

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Author information

Authors and Affiliations

  1. Department of Neurology, University Hospital at Heidelberg, Germany

    Peter D. Schellinger MD, PhD

  2. Department of Neurology, Georgetown University, Washington, DC

    Chelsea S. Kidwell MD

  3. National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD

    Steven Warach MD, PhD

Authors
  1. Peter D. Schellinger MD, PhD
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  2. Chelsea S. Kidwell MD
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  3. Steven Warach MD, PhD
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Editor information

Editors and Affiliations

  1. USCD Stroke Center, University of California, San Diego

    Patrick D. Lyden MD

  2. Veteran’s Affairs Medical Center, San Diego, CA

    Patrick D. Lyden MD

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© 2005 Humana Press Inc., Totowa, NJ

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Schellinger, P.D., Kidwell, C.S., Warach, S. (2005). Using Magnetic Resonance Imaging to Select and Manage Patients for Treatment. In: Lyden, P.D. (eds) Thrombolytic Therapy for Acute Stroke. Current Clinical Neurology. Humana Press. https://doi.org/10.1385/1-59259-933-8:279

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  • DOI: https://doi.org/10.1385/1-59259-933-8:279

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-398-5

  • Online ISBN: 978-1-59259-933-2

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