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Computational model of insulin-glucose regulatory system to represent type 1 diabetes mellitus, hypoglycemia and hyperinsulinemia

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Abstract

Diabetes mellitus (DM) is probably one of the most popular diseases among people. In this disorder, a malfunction occurs in the insulin-glucose regulatory system. To model the DM pathophysiology, we propose a computational model for the insulin-glucose regulatory system. In this differential equation model, the complex behavior of this biological system has been considered. This model shows chaos and bifurcating properties which have been seen in dynamical diseases. We have analyzed static and dynamical properties of the proposed model to show its strength and capability to represent different types of diabetes and other dysfunction in the insulin-glucose system.

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Authors and Affiliations

  1. Department of Electrical Engineering, University of Basrah, Basrah, Iraq

    Ahmed Mohammed Ali & Fadhil Rahma Tahir

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  1. Ahmed Mohammed Ali
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  2. Fadhil Rahma Tahir
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Correspondence to Ahmed Mohammed Ali.

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Ali, A.M., Tahir, F.R. Computational model of insulin-glucose regulatory system to represent type 1 diabetes mellitus, hypoglycemia and hyperinsulinemia. Eur. Phys. J. Spec. Top. 229, 943–952 (2020). https://doi.org/10.1140/epjst/e2020-900098-6

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  • DOI: https://doi.org/10.1140/epjst/e2020-900098-6

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