Skip to main content
Log in

Shape instabilities in vesicles: A phase-field model

  • Published:
The European Physical Journal Special Topics Aims and scope Submit manuscript

Abstract.

A phase field model for dealing with shape instabilities in fluid membrane vesicles is presented. This model takes into account the Canham-Helfrich bending energy with spontaneous curvature. A dynamic equation for the phase-field is also derived. With this model it is possible to see the vesicle shape deformation dynamically, when some external agent instabilizes the membrane, for instance, inducing an inhomogeneous spontaneous curvature. The numerical scheme used is detailed and some stationary shapes are shown together with a shape diagram for vesicles of spherical topology and no spontaneous curvature, in agreement with known results.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • M. Edidin, Nat. Rev. Mol. Cell Biol. 4, 414 (2003)

    Article  Google Scholar 

  • S. Leibler, Equilibrium statistical mechanics of fluctuating films and membranes, in Statistical Mechanics of Membranes and Surfaces, edited by D. Nelson, S. Weinberg (World Scientific, 1989) pp. 45–103

  • S.A. Safran, Statistical Thermodynamics of Surfaces Interfaces, and Membranes, Frontiers in Physics No. 90 (Addison-Wesley, 1994)

  • R. Lipowsky, E. Sackmann, (Eds.) Structure and Dynamics of Membranes, Handbook of Biological Physics (Elsevier Science, 1995)

  • B. Alberts et al., Molecular Biology of the Cell, 4th edn. (Garland Science, 2002)

  • J. Israelachvili, Intermolecular and Surface Forces, 2nd edn. (Academic Press, 1992)

  • J. Zimmerberg, M.M. Kozlov, Nature Rev. Mol. Cell Biol. 7, 9 (2006)

    Article  Google Scholar 

  • U. Seifert, Adv. Phys. 46, 13 (1997)

    Article  ADS  Google Scholar 

  • S.A. Safran, Adv. Phys. 48, 395 (1999)

    Article  ADS  Google Scholar 

  • P. Canham, J. Theor. Biol. 26, 61 (1970)

    Article  Google Scholar 

  • W. Helfrich, Z. Naturforsch. C 28, 693 (1973)

    Google Scholar 

  • K. Brakke, Exp. Math. 1, 141 (1992)

    MATH  MathSciNet  Google Scholar 

  • F. Campelo, A. Hernández-Machado, Eur. Phys. J. E 20, 37 (2006)

    Article  Google Scholar 

  • I. Tsafrir et al., Phys. Rev. Lett. 86, 1138 (2001)

    Article  ADS  Google Scholar 

  • I. Tsafrir, Shape Instabilities of Membranes with Anchored Polymers under Geometric Constraints, Ph.D. thesis (Weizmann Institute of Science, 2003)

  • I. Tsafrir, Y. Caspi, M.A. Guedeau-Boudeville, T. Arzi, J. Stavans, Phys. Rev. Lett. 91, 138102 (2003)

    Article  ADS  Google Scholar 

  • H. Ringsdorf, B. Schlarb, J. Venzmer, Angew. Chem. Int. Ed. Engl. 27, 113 (1988)

    Article  Google Scholar 

  • J. Langer, in Directions in Condensed Matter Physics, edited by G. Grinstein G. Mazenko (World Scientific, 1986)

  • R. González-Cinca et al., in Advances in Condensed Matter and Statistical Physics, edited by E. Korutcheva, R. Cuerno (Nova Science Publishers, 2004) pp. 203–236, http://arxiv.org/abs/cond-mat/0305058

  • M. Alava, M. Dubé, M. Rost, Adv. Phys. 53, 83 (2004)

    Article  ADS  Google Scholar 

  • M. Kraus, W. Wintz, U. Seifert, R. Lipowsky, Phys. Rev. Lett. 77, 3685 (1996)

    Article  ADS  Google Scholar 

  • M. do Carmo, Differential Geometry of Curves and Surfaces (Prentince-Hall, 1976)

  • G. Foltin, Phys. Rev. E 49, 5243–5248 (1994)

    Article  ADS  Google Scholar 

  • T. Taniguchi, Phys. Rev. Lett. 76, 4444 (1996)

    Article  ADS  Google Scholar 

  • Q. Du, C. Liu, X. Wang, J. Comput. Phys. 121, 757 (2006)

    Article  ADS  Google Scholar 

  • E. Evans, W. Rawicz, Phys. Rev. Lett. 64, 2094 (1990)

    Article  ADS  Google Scholar 

  • J.C. Strikwerda, Finite Difference Schemes and Partial Differential Equations (Wadsworth & Brooks, 1989)

  • D.P. Bertsekas, Nonlinear Programming, 2nd edn. (Athena Scientific, 1999)

  • U. Seifert, K. Berndl, R. Lipowsky, Phys. Rev. A 44, 1182 (1991)

    Article  ADS  MathSciNet  Google Scholar 

  • R.D. Kamien, Rev. Mod. Phys. 74, 953 (2002)

    Article  ADS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Campelo, F., Hernández-Machado, A. Shape instabilities in vesicles: A phase-field model. Eur. Phys. J. Spec. Top. 143, 101–108 (2007). https://doi.org/10.1140/epjst/e2007-00077-y

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1140/epjst/e2007-00077-y

Keywords

Navigation