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The role of miRNAs in the development of prostate cancer

  • Reviews and Theoretical Articles
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Abstract

MicroRNAs (miRNAs) act as key post-transcriptional regulators of gene expression. This review examines current advances in the study of the role of miRNAs in cancer, including prostate cancer. Issues devoted to the nomenclature, biogenesis, the role of miRNAs as oncogenes and tumor suppressors, and their role in the diagnosis, treatment, and prognosis of prostate cancer are discussed. Assessment of the role of miRNAs in the development of prostate cancer will promote early diagnosis and will be important for the development of new approaches to the disease treatment.

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Authors and Affiliations

  1. Department of Genetics, Bashkir State University, Ufa, 450074, Russia

    G. B. Kunsbaeva, I. R. Gilyazova & E. K. Khusnutdinova

  2. Institute of Biochemistry and Genetics, Ufa Scientific Center, Russian Academy of Sciences, Ufa, 450054, Bashkortostan Republic, Russia

    I. R. Gilyazova & E. K. Khusnutdinova

  3. Department of Urology, Bashkir State Medical University, Ufa, 450000, Russia

    V. N. Pavlov

Authors
  1. G. B. Kunsbaeva
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  2. I. R. Gilyazova
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  3. V. N. Pavlov
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  4. E. K. Khusnutdinova
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Correspondence to G. B. Kunsbaeva.

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These authors contributed equally to this work.

Original Russian Text © G.B. Kunsbaeva, I.R. Gilyazova, V.N. Pavlov, E.K. Khusnutdinova, 2015, published in Genetika, 2015, Vol. 51, No. 7, pp. 737–753.

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Kunsbaeva, G.B., Gilyazova, I.R., Pavlov, V.N. et al. The role of miRNAs in the development of prostate cancer. Russ J Genet 51, 627–641 (2015). https://doi.org/10.1134/S102279541507008X

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  • DOI: https://doi.org/10.1134/S102279541507008X

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