Abstract
In order to evaluate the results, we reviewed all 34 patients treated in our hospital for endophthalmitis after cataract surgery between January 1994 and January 1998. After cultures were taken, all patients received intraocular, subconjunctival and topical vancomycin and ceftazidime. Additionally, twelve patients received the same antibiotics systemically. Besides steroids were administered in all patients. In 79% of the patients the bacterial culture was positive. Coagulase negative Staphylococcus was the most frequently isolated microorganism (48%). After treatment a visual acuity of 0.1 or more was achieved in 62% of the patients. The best final results were achieved in the patients with an initial visual acuity of 1/300 or more, and in the patients from whom a coagulase negative Staphylococcus was isolated.
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Kattan HM, Flynn HW, Pflugfelder SC, Robertson C, Forster RK. Nosocomial endophthalmitis survey: current incidence of infection after intraocular surgery. Ophthalmology 1991; 98: 227–238.
Powe NR, Schein OD, Gieser SC, Tielsch JM, Luthra R, Javitt J, Steinberg EP. Synthesis of the literature on visual acuity and complications following cataract extraction with intraocular lens implantation. Arch Ophthalmol 1994; 112: 239–252.
Menikoff JA, Speaker MG, Marmor MM, Raskin EM. A case-control study of risk factors for postoperative endophthalmitis. Ophthalmology 1991; 98: 1761–1768.
Norregaard JC, Thoning H, Bernth-Petersen P. Andersen TF, Javitt JC, Anderson GF. Risk of endophthalmitis after cataract extraction: results from the international cataract surgery outcomes study. Br J Ophthalmol 1997; 81: 102–106.
Driebe WT, Mandelbaum S, Forster RK, Schwartz LK, Culbertson WW. Pseudophacic endophthalmitis diagnosis and management. Ophthalmology 1986; 93: 442–448.
Endophthalmitis vitrectomy study group. Results of the endophthalmitis vitrectomy study: a randomized trial of immediate vitrectomy and of intravenous antibiotics for the treatment of postoperative bacterial endophthalmitis. Arch Ophthalmol 1995; 113: 1479–1496.
Heaven CJ, Mann PJ, Boase DL. Endophthalmitis following extracapsular cataract surgery: a review of 32 cases. Br J Ophthalmol 1992; 76: 419–423.
Doft BH, Kelsey SF, Wisniewski S. Metz DJ, Lobes L, Rinkoff J, Davis M, Kassoff A. Treatment of endophthalmitis after cataract extraction. Retina 1994; 14: 297–304.
Bohigian GM, Olk J. Factors associated with a poor visual result in endophthalmitis. Am J Ophthalmol 1986; 101: 332–341.
Olson JC, Flynn HW, Forster RK, Culbertson WW. Results in the treatment of postoperative endophthalmitis. Ophthalmology 1983; 90: 692–699.
Schulman JA, Peyman GA. Intravitreal corticosteroids as an adjunct in the treatment of bacterial and fungal endophthalmitis: a review. Retina 1992; 12: 336–340.
Pflugfelder SC, Hernández E, Fliesler SJ, Álvarez J, Pflugfelder ME, Forster RK. Intravitreal vancomycin: Retinal toxicity, clearance, and interaction with gentamycin. Arch Ophthalmol 1987; 105: 831–837.
Aguilar HE, Meredith TA, Drews C, Grossniklaus H, Sawant AD, Gardner S. Comparative treatment of experimental staphylococcus aureus endophthalmitis. Am J Ophthalmol 1996; 121: 310–317.
Campachiaro PA, Lim JI, the aminoglycoside toxicity study group. Aminoglycoside toxicity in the treatment of endophthalmitis. Arch Ophthalmol 1994; 112: 48–53.
Aaberg TM, Flynn HW, Murray TG. Intraocular ceftazidime as an alternative to the aminoglycosides in the treatment of endophthalmitis. Arch Ophthalmol 1994; 112: 18–19.
Doft BH, Barza M. Ceftazidime or amikacin: choice of intravitreal antimicrobials in the treatment of postoperative endophthalmitis. Arch Ophthalmol 1994; 112: 17–18.
Meredith TA, Aguilar HE, Shaarawy A, Kincaid M, Dick J, Niesman MR. Vancomycin levels in the vitreous cavity after intravenous administration. Am J Ophthalmol 1995; 119: 774–778.
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Versteegh, M., Hooymans, J., Renardel De Lavalette, V. et al. Acute bacterial endophthalmitis after cataract extraction. Doc Ophthalmol 100, 7–15 (2000). https://doi.org/10.1023/A:1001727208261
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DOI: https://doi.org/10.1023/A:1001727208261