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Pairwise alignment of the DNA sequence using hypercomplex number representation

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Abstract

A new set of DNA base-nucleic acid codes and their hypercomplex number representation have been introduced for taking the probability of each nucleotide into full account. A new scoring system has been proposed to suit the hypercomplex number representation of the DNA base-nucleic acid codes and incorporated with the method of dot matrix analysis and various algorithms of sequence alignment. The problem of DNA sequence alignment can be processed in a rather similar way to pairwise alignment of the protein sequence.

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Authors and Affiliations

  1. School of Mechanical and Production Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore, 639798, Singapore

    Jian-Jun Shu & Li Shan Ouw

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  1. Jian-Jun Shu
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  2. Li Shan Ouw
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Correspondence to Jian-Jun Shu.

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Shu, JJ., Ouw, L.S. Pairwise alignment of the DNA sequence using hypercomplex number representation. Bull. Math. Biol. 66, 1423–1438 (2004). https://doi.org/10.1016/j.bulm.2004.01.005

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  • DOI: https://doi.org/10.1016/j.bulm.2004.01.005

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