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Phenolic Content, Lipid Peroxidation Inhibition and Antioxidant Potential of Leaf Essential Oil of Ginkgo biloba in Various Scavenging Models

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Abstract

Current study was aimed to evaluate antioxidant and lipid peroxidation inhibition efficacy of Ginkgo biloba leaf essential oil (GBEO) in different radical scavenging models along with total phenolic content. The GBEO exhibited potent antioxidant effect on the inhibition of DPPH, NO, O2−, and OH− radicals by 75.47, 72.42, 72.24 and 73.67%, whereas IC50 values of GBEO were found to be 222.08, 247.23, 132.85, and 305.06 μg/ml, respectively. In addition, the GBEO evoked significant reducing power efficacy and profound inhibitory effect on lipid-peroxidation induced by ferric ions in a dose-dependent manner. Moreover, the GBEO yielded 8.60 ± 0.01 mg/g GAE phenolic contents, confirming its role as a natural antioxidant.

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References

  1. Valko M, Leibfritz D, Moncola J, Cronin MTD, Mazura M, Telser J (2007) Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39:44–84

    Article  CAS  PubMed  Google Scholar 

  2. Halliwell B (1991) Reactive oxygen species in living systems: source, biochemistry and role in human disease. Am J Med 91:14S–22S

    Article  CAS  PubMed  Google Scholar 

  3. Velioglu Y, Mazza G, Gao L, Oomah B (1998) Antioxidant activity and total phenolics in selected fruits, vegetables and grain products. J Agric Food Chem 46:4113–4117

    Article  CAS  Google Scholar 

  4. Bajpai VK, Al-Reza SM, Choi UK, Lee JH, Kang SC (2009) Chemical composition, antibacterial and antioxidant activities of leaf essential oil and extracts of Metasequoia glyptostroboides Miki ex Hu. Food Chem Toxicol 47:1876–1883

    Article  CAS  PubMed  Google Scholar 

  5. Losso JN, Shahidi F, Bagchi D (2007) Anti-angiogenic functional and medicinal foods. CRC Press, Boca Raton, pp 138–148

    Book  Google Scholar 

  6. Pietri S, Maurelli E, Drieu K, Culcasi M (1997) Cardioprotective and anti-oxidant effects of the terpenoid constituents of Ginkgo biloba extract (EGb 761). J Mol Cell Cardiol 29:733–742

    Article  CAS  PubMed  Google Scholar 

  7. Naik SR, Panda VS (2007) Antioxidant and hepatoprotective effects of Ginkgo biloba phytosomes in carbon tetrachloride-induced liver injury in rodents. Liver Int 27:393–399

    Article  CAS  PubMed  Google Scholar 

  8. Bajpai VK, Sharma A, Baek KH (2015) Antibacterial mode of action of Ginkgo biloba leaf essential oil: effect on morphology and membrane permeability. Bang J Pharmacol 10:337–350

    Google Scholar 

  9. Bajpai VK, Sharam A, Kim SH, Kim JJ, Baek KH (2013) Microwave-assisted seed essential oil of Eleutherococcus senticosus and its antioxidant and free radical scavenging activities. J Food Biochem 37:119–127

    Article  CAS  Google Scholar 

  10. Devasagayam TPA, Tilak JC, Boloor KK, Sane KS, Ghaskadbi SS, Lele RD (2004) Free radicals and antioxidants in human health: current status and future prospects. J Assoc Phys India 52:794–804

    CAS  Google Scholar 

  11. Hernandez EH, Alquicira EP, Flores MEJ, Legarreta IG (2009) Antioxidant effect rosemary (Rosmarinus officinalis L.) and oregano (Origanum vulgare L.) extracts on TBARS and colour of model raw pork batters. Meat Sci 81:410–417

    Article  Google Scholar 

  12. Gramza A, Khokhar S, Hes M, Golinska AJ (2004) Polyphenols potential food improvement factor. Pol J Environ Stud 13:143–146

    Google Scholar 

  13. Qian ZJ, Kang KH, Kim SK (2012) Isolation and antioxidant activity evaluation of two new phthalate derivatives from seahorse, Hippocampus kuda Bleeler. Biotechnol Bioprocess Eng 17:1031–1040

    Article  CAS  Google Scholar 

  14. McLaurin J, Golomb R, Jurewicz A, Antel JP, Fraser PE (2002) Inositol stereoisomers stabilize an oligomeric aggregate of alzheimer amyloid β peptide and inhibit Aβ-induced toxicity. J Biol Chem 275:18495–18502

    Article  Google Scholar 

  15. Beena Kumar D, Rawat DS (2013) Synthesis and antioxidant activity of thymol and carvacrol based Schiff bases. Bioorg Med Chem Lett 23:641–645

    Article  CAS  PubMed  Google Scholar 

  16. Cetinkaya O, Duru ME, Ciçek H (2012) Synthesis and characterization of boronic acid functionalized macroporous uniform poly (4-chloromethylstyrene-co-divinylbenzene) particles and its use in the isolation of antioxidant compounds from plant extracts. J Chromatogr B Analyt Technol Biomed Life Sci 15:51–60

    Article  Google Scholar 

  17. Rani MP, Padmakumari KP (2012) HPTLC and reverse phase HPLC methods for the simultaneous quantification and in vitro screening of antioxidant potential of isolated sesquiterpenoids from the rhizomes of Cyperus rotundus. J Chromatogr B Analyt Technol Biomed Life Sci 1:22–28

    Article  Google Scholar 

  18. Kacem M, Kacem I, Simon G, Mansour AB, Chaabouni S, Elfeki A, Bouaziz M (2015) Phytochemicals and biological activities of Ruta chalepensis L. growing in Tunisia. Food Biosci. doi:10.1016/j.fbio.2015.08.001

    Google Scholar 

Download references

Acknowledgement

This work was carried out with the support of “Cooperative Research Program for Agriculture Science and Technology Development (Project No. PJ010934)” Rural Development Administration, Republic of Korea.

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Authors and Affiliations

  1. School of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk, 712-749, Korea

    Vivek K. Bajpai & Kwang-Hyun Baek

  2. Biological and Genetic Resources Assessment Division, National Institute of Biological Resources, Incheon, 22689, Korea

    Yangseon Kim

Authors
  1. Vivek K. Bajpai
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  2. Yangseon Kim
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  3. Kwang-Hyun Baek
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Correspondence to Vivek K. Bajpai or Kwang-Hyun Baek.

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Bajpai, V.K., Kim, Y. & Baek, KH. Phenolic Content, Lipid Peroxidation Inhibition and Antioxidant Potential of Leaf Essential Oil of Ginkgo biloba in Various Scavenging Models. Natl. Acad. Sci. Lett. 40, 95–99 (2017). https://doi.org/10.1007/s40009-016-0530-5

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  • DOI: https://doi.org/10.1007/s40009-016-0530-5

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