Skip to main content

Advertisement

SpringerLink
Log in

Methylprednisolone combined vitamin supplementation reversed rapidly subacute combined degeneration of the spinal cord induced by the abuse of nitrous oxide

  • Letter to the Editor
  • Published:
Acta Neurologica Belgica Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Availability of data and materials

All data are fully available without restriction.

Code availability

Not applicable.

References

  1. Lan SY, Kuo CY, Chou CC, Kong SS, Hung PC, Tsai HY, Chen YC, Lin JJ, Chou IJ, Lin KL (2019) Recreational nitrous oxide abuse related subacute combined degeneration of the spinal cord in adolescents—a case series and literature review. Brain Dev 41:428–435. https://doi.org/10.1016/j.braindev.2018.12.003

    Article  PubMed  Google Scholar 

  2. Savage S, Ma D (2014) The neurotoxicity of nitrous oxide: the facts and “putative” mechanisms. Brain Sci 4:73–90. https://doi.org/10.3390/brainsci4010073

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Zheng D, Ba F, Bi G, Guo Y, Gao Y, Li W (2020) The sharp rise of neurological disorders associated with recreational nitrous oxide use in China: a single-center experience and a brief review of Chinese literature. J Neurol 267:422–429. https://doi.org/10.1007/s00415-019-09600-w

    Article  PubMed  Google Scholar 

  4. Yilmaz C, Karali K, Fodelianaki G, Gravanis A, Chavakis T, Charalampopoulos I, Alexaki VI (2019) Neurosteroids as regulators of neuroinflammation. Front Neuroendocrinol 55:100788. https://doi.org/10.1016/j.yfrne.2019.100788

    Article  PubMed  Google Scholar 

  5. Guennoun R (2020) Progesterone in the brain: hormone, neurosteroid and neuroprotectant. Int J Mol Sci 21:100788. https://doi.org/10.3390/ijms21155271

    Article  CAS  Google Scholar 

Download references

Acknowledgements

The authors thank the patient for allowing us to publish this case report.

Funding

Not applicable.

Author information

Authors and Affiliations

  1. Department of Neurology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China

    Shaoru Zhang, Zhihua Zhou, Weifeng Wu, Qingyun Yu & Mingfan Hong

Authors
  1. Shaoru Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Zhihua Zhou
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Weifeng Wu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Qingyun Yu
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Mingfan Hong
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

SZ and ZZ carried out data collection and drafted the manuscript. WW and QY participated in data collection and interpreted the data. MH conceived, designed the research and interpreted the data and made critical revisions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Mingfan Hong.

Ethics declarations

Conflict of interest

We declare that they have no conflict of interest or competing interests.

Ethics approval

A formal ethical review by an ethics committee was not required because this is a case report.

Consent to participate

The patient understand the contents of this treatment, including the risks and benefits of methylprednisolone therapy.

Consent for publication

Written informed consent was obtained from the patient for publication of this case report and accompanying images.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Zhang, S., Zhou, Z., Wu, W. et al. Methylprednisolone combined vitamin supplementation reversed rapidly subacute combined degeneration of the spinal cord induced by the abuse of nitrous oxide. Acta Neurol Belg 122, 1353–1355 (2022). https://doi.org/10.1007/s13760-020-01589-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13760-020-01589-8

Keywords

Search

Navigation