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Atypical triad of IgA nephropathy: reversible acute kidney injury, gross hematuria, and severe bilateral flank pain

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Abstract

Reversible acute kidney injury very rarely complicates the course of immunoglobulin A (IgA) nephropathy. We report an atypical case of reversible acute kidney injury, gross hematuria, and severe bilateral flank pain as the presenting triad of IgA nephropathy. Renal biopsy revealed mesangial IgA deposition without glomerular crescents. The patient’s renal dysfunction, mediated by red cell tubular obstruction, interstitial nephritis, and tubular necrosis, resolved without intervention. We conclude that IgA nephropathy should be considered in the differential diagnosis for transient acute kidney injury with gross hematuria, and should be appropriately treated based on known prognostic factors.

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Conflict of interest

All the authors have declared no competing interests.

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Authors and Affiliations

  1. Department of Internal Medicine, St. Mary’s Medical Center, 450 Stanyan Street, San Francisco, CA, 94117, USA

    Susan Kim & Warren Chang

  2. Division of Nephrology, St. Mary’s Medical Center, San Francisco, CA, 94117, USA

    Warren Chang

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  1. Susan Kim
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  2. Warren Chang
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Correspondence to Susan Kim.

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Kim, S., Chang, W. Atypical triad of IgA nephropathy: reversible acute kidney injury, gross hematuria, and severe bilateral flank pain. CEN Case Rep 3, 145–147 (2014). https://doi.org/10.1007/s13730-013-0106-x

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  • DOI: https://doi.org/10.1007/s13730-013-0106-x

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