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Gastric Microbiota and Morphological Changes of the Gastroduodenal Tract Associated with Helicobacter Pylori Infection

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Abstract

Investigation of the microbiota at morphological changes of a gastrointestinal tract. One hundred four patients were examined by cytologic, bacteriological methods, and mass-spectrometry techniques. Studying of the microbial association of stomach has demonstrated the mixed microflora presented by Helicobacter pylori, cocci, fungi Candida, rods, and protozoa. Bacteria of the following species were found: Actinomyces, Arthrobacter, Bacillus, Corynebacterium, Lactobacillus, Neisseria, Pseudomonas, Rothia, Staphylococcus, Streptococcus, and Streptomyces. The microbial flora of esophageal samples was less various (opportunistic bacteria Neisseria, Gemella, and Rothia mucilaginosa were revealed). In group of Helicobacter-positive patients, bacteria were found in fungi Candida, Colletotrichum, and bacterias Thauera and Mycoplasma, while in H.pylori-negative patients, samples have more different species. Intensity of morphological changes (the atrophy, the intestinal metaplasia, and the dysplasia) correlated with a frequency of detection of H. pylori and eukaryotic microbiota (fungi Candida and protozoa).

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References

  1. Zilberstein, B., Quintanilha, A. G., Santos, M. A., et al. (2007). Digestive tract microbiota in healthy volunteers. Clinics (São Paulo, Brazil), 62, 47–54.

    Article  Google Scholar 

  2. Delgado, S., Cabrera-Rubio, R., Mira, A., Suárez, A., Mayo, B. (2013). Microbiological survey of the human gastric ecosystem using culturing and pyrosequencing methods. Microbial Ecology, 65, 763–772.

    Article  Google Scholar 

  3. Andersson, A. F., Lindberg, M., Jakobsson, H., et al. (2008). Comparative analysis of human gut microbiota by barcoded pyrosequencing. PloS One, 3(7), e2836.

    Article  Google Scholar 

  4. Li, X. X., Wong, G. L., To, K. F., et al. (2009). Bacterial microbiota profiling in gastritis without Helicobacter pylori infection or non-steroidal anti-inflammatory drug use. PloS One, 4, e7985.

    Article  Google Scholar 

  5. Maldonado-Contreras, A., Goldfarb, K. C., Godoy-Vitorino, F., et al. (2011). Structure of the human gastric bacterial community in relation to Helicobacter pylori status. The ISME Journal, 5, 574–579.

    Article  Google Scholar 

  6. Khosravi, Y., Dieye, Y., Poh, B. H., et al. (2014). Culturable bacterial microbiota of the stomach of Helicobacter pylori positive and negative gastric disease patients. Scientific World Journal, 2014, 610421.

    Google Scholar 

Download references

Acknowledgments

RAA was supported by the Program of Competitive Growth of Kazan Federal University and subsidy allocated to Kazan Federal University for the state assignment in the sphere of scientific activities.

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Authors and Affiliations

  1. Kazan Scientific Research Institute of Epidemiology and Microbiology, Bolshaya Krasnaya str. 67, Kazan, 420015, Russia

    Guzel Isaeva

  2. Center of Hygiene and Epidemiology in the Republic of Tatarstan, Sechenov str., 13A, Kazan, 420061, Russia

    Lidia Vakatova

  3. Medical Center «Pharm-T» (Kazan), Astronomicheskaya str., 13/30, Kazan, 420111, Russia

    Nadejda Efimova

  4. Kazan Federal University, Kremlevskaya str., 18, Kazan, 420008, Russia

    Albert Rizvanov

  5. Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan, Orenburgskiy trakt, 138, Kazan, 420064, Russia

    Inna Valiullina

Authors
  1. Guzel Isaeva
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  2. Lidia Vakatova
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  3. Nadejda Efimova
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  4. Albert Rizvanov
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  5. Inna Valiullina
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Correspondence to Guzel Isaeva.

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The authors declare no conflicts of interest.

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Isaeva, G., Vakatova, L., Efimova, N. et al. Gastric Microbiota and Morphological Changes of the Gastroduodenal Tract Associated with Helicobacter Pylori Infection. BioNanoSci. 6, 483–486 (2016). https://doi.org/10.1007/s12668-016-0260-7

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  • DOI: https://doi.org/10.1007/s12668-016-0260-7

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