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Epidemiological Analysis of Cleft Lip and/or Palate by Cleft Pattern

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Abstract

Objectives

To analyze gender differences in cleft pattern by the clinical statistical study of Japanese patients with cleft lip and/or cleft palate.

Study design

Cleft pattern modeling was used to analyze 782 patients with cleft lip and/or cleft palate (417 males and 365 females) who had been examined at the Cleft Lip and Palate Center, Aichi-Gakuin University Hospital, and whose details could be confirmed. Relationships between gender and cleft type were analyzed with chi-squared test.

Results

A comparison of gender differences by cleft type revealed that a greater percentage of males had milder cleft lip, cleft lip and palate, or cleft palate, whereas the percentage of females tended to be greater as cleft severity increased.

Conclusions

Modeling of cleft patterns enables more detailed classification of cleft lip and palate, and can lead to a greater understanding of pathology.

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References

  1. Natsume N, Suzuki T, Kawai T (1984) Clinical analysis of the cleft patterns of lip and palate. Congenit Anom 24:75–82

    Article  Google Scholar 

  2. Natsume N, Miura S, Kawai T (1989) Effect of sexual differences on the development of cleft palate in the human. Plast Reconstr Surg 84:854–855

    PubMed  CAS  Google Scholar 

  3. Natsume N, Niimi T, Furukawa H (2001) Survery of congenital anomalies associated with cleft lip and/or palate in 701, 181 Japanese people. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 191:157–161

    Article  Google Scholar 

  4. Aragaki K, Sunakawa H, Hiratsuka H (2003) A sixteen-year clinicostatistical analysis of cleft lip and/or palate patients in Department of Oral and Maxillofacial Surgery, School of Medicine, University of the Ryukyus. J Jpn Cleft Palate Assoc 28:66–73

    Google Scholar 

  5. Otsuki R, Morita N, Wada T (2002) Clinical and statistical observations of patients with cleft lip and/or palate:-1st report: character of cleft type and complicating malformations. J Jpn Stomatol Soc 51(2):132–136

    Google Scholar 

  6. Conway H, Wagner KJ (1966) Incidence of cleft in New York City. Cleft Palate J 3:284–290

    PubMed  CAS  Google Scholar 

  7. Loretz W, Westmorland WW, Richards LF (1961) A study of cleft lip and cleft palate births in California, 1995. Am J Public Health 51:873–877

    Article  CAS  Google Scholar 

  8. Mossey PA, Little J, Munger RG (2009) Cleft lip and palate. Lancet 374(9703):1773-1785. Epub 2009

    Google Scholar 

  9. Hirayama K (1971) Anatomical studies on the development of the facial artery and its distribution in the cleft lip of the human fetus. Part 1 Development of the facial artery in the human fetus on the latter stage of pregnancy. Med J Kagoshima Univ 1:295–316

    Google Scholar 

  10. Natsume N, Kaetsu A, Kanoh Y (1988) Regularity in the development of cleft lip and/or palate patterns. Aichi Gakuin Dent Sci 1(1):54–64

    Google Scholar 

  11. Meskin LH, Pruzansky S, Gullen WH (1968) An epidemiologic investigation of factors related to the extent of facial clefts. I. Sex of patient. Cleft Palate J 5:23–29

    PubMed  CAS  Google Scholar 

  12. Ueda T, Kadomatsu K, Morita M (2006) Study of cleft lip and/or palate, relation of cleft types with sex. Showa Univ J Med Sci 66(3):194–199

    Google Scholar 

  13. Miura S, Natsume N, Horiuchi R (1990) Experimental study on cleft lip and palate. Preventive effects of estradiol on cleft lip and/or palate in A/J mice. J Jpn Cleft Palate Assoc 15(2):122–131

    Google Scholar 

  14. Ross RB, Johnston MC (1972) Cleft lip and palate. Williams & Wilkins, Baltimore

    Google Scholar 

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Correspondence to Nagato Natsume.

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Nagase, Y., Natsume, N., Kato, T. et al. Epidemiological Analysis of Cleft Lip and/or Palate by Cleft Pattern. J. Maxillofac. Oral Surg. 9, 389–395 (2010). https://doi.org/10.1007/s12663-010-0132-6

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  • DOI: https://doi.org/10.1007/s12663-010-0132-6

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