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Seroprevalence of toxoplasmosis in diabetic pregnant women in southwestern of Iran

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Abstract

To investigate anti-Toxoplasma gondii IgG and IgM antibodies in diabetic pregnant women in Ahvaz, southwest of Iran this experiment was performed. In current study the sera of 110 diabetic pregnant women as well as 110 non diabetic pregnant women referred to the hospitals affiliated with the Ahvaz Jundishapur University of Medical Sciences were assessed for anti-T. gondii IgG and IgM antibodies by ELISA and IFA methods. The ELISA assessments showed that 47 (42.7 %) and 3 (2.7 %) of diabetic women were positive for IgG and IgM antibodies, respectively. However, in the control group, 24 individuals (21.81 %) were positive for IgG antibody but no detection for IgM antibody. According to IFA method, 46 (41.8 %) and 3 (2.7 %) of diabetic women were positive for IgG and IgM antibodies, respectively, while in control group, 21 individuals (19.09 %) were positive for IgG antibody. In this method, IgM antibody was negative for all samples of control group (0 %). In both methods, the values obtained in the case group were significantly higher than those in the control group (p < 0.05). Prevalence of anti-Toxoplasma IgG and IgM antibodies in diabetic pregnant women was higher than that in non-diabetic pregnant women. It seems that screening tests for seeking patients and teaching the transmission routes should be considered as prenatal cares for diabetic women.

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Acknowledgments

We thank honorable colleagues and staff of laboratory, internal and gynecology departments, diabetes clinics, Golestan, Imam Khomeini, Razi, Aria hospitals and Matorian private Medical Diagnostic Laboratory for their cooperation in selecting study subjects and providing samples. This research was financially supported by the Research Department of Ahvaz Jundishapur University of Medical Sciences (No. D89015).

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Authors and Affiliations

  1. Department of Medical Parasitology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, P. O. Box: 613715794, Ahvaz, Islamic Republic of Iran

    Jasem Saki, Shahla Shafieenia & Masoud Foroutan-Rad

  2. Health Institute, Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Islamic Republic of Iran

    Jasem Saki

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  1. Jasem Saki
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  2. Shahla Shafieenia
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Correspondence to Jasem Saki.

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The authors declare that they have no conflict of interest.

Ethical Statement

Before collecting blood samples a written informed consent was obtained from all individual participants included in the study. It is worth mentioning that present study was approved by the ethic committee of Ahvaz Jundishapur University of Medical Sciences (No. ETH-1392.121).

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Saki, J., Shafieenia, S. & Foroutan-Rad, M. Seroprevalence of toxoplasmosis in diabetic pregnant women in southwestern of Iran. J Parasit Dis 40, 1586–1589 (2016). https://doi.org/10.1007/s12639-015-0735-4

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  • DOI: https://doi.org/10.1007/s12639-015-0735-4

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