Skip to main content
SpringerLink
Log in

Uveitis in juvenile idiopathic arthritis

  • Viewpoint
  • Published:
World Journal of Pediatrics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Marino A, Weiss PF, Davidson SL, Lerman MA. Symptoms in noninfectious uveitis in a pediatric cohort: initial presentation versus recurrences. J AAPOS. 2019;23:220.e1-6.

    Google Scholar 

  2. Rosenbaum JT, Dick AD. The eyes have it: a rheumatologist's view of uveitis. Arthritis Rheumatol. 2018;70:1533–43.

    Google Scholar 

  3. Saurenmann RK, Levin AV, Feldman BM, Rose JB, Laxer RM, Schneider R, et al. Prevalence, risk factors, and outcome of uveitis in juvenile idiopathic arthritis: a long-term followup study. Arthritis Rheum. 2007;56:647–57.

    CAS  Google Scholar 

  4. Heiligenhaus A, Heinz C, Edelsten C, Kotaniemi K, Minden K. Review for disease of the year: epidemiology of juvenile idiopathic arthritis and its associated uveitis: the probable risk factors. Ocul Immunol Inflamm. 2013;21:180–91.

    Google Scholar 

  5. de Smet MD, Taylor SR, Bodaghi B, Miserocchi E, Murray PI, Pleyer U, et al. Understanding uveitis: the impact of research on visual outcomes. Prog Retin Eye Res. 2011;30:452–70.

    Google Scholar 

  6. Dana MR, Merayo-Lloves J, Schaumberg DA, Foster CS. Visual outcomes prognosticators in juvenile rheumatoid arthritis-associated uveitis. Ophthalmology. 1997;104:236–44.

    CAS  Google Scholar 

  7. Moradi A, Amin RM, Thorne JE. The role of gender in juvenile idiopathic arthritis-associated uveitis. J Ophthalmol. 2014;2014:461078.

    Google Scholar 

  8. Saurenmann RK, Levin AV, Feldman BM, Laxer RM, Schneider R, Silverman ED. Risk factors for development of uveitis differ between girls and boys with juvenile idiopathic arthritis. Arthritis Rheum. 2010;62:1824–8.

    CAS  Google Scholar 

  9. Angeles-Han ST, Pelajo CF, Vogler LB, Rouster-Stevens K, Kennedy C, Ponder L, et al. Risk markers of juvenile idiopathic arthritis-associated uveitis in the childhood arthritis and rheumatology research alliance (CARRA) registry. J Rheumatol. 2013;40:2088–96.

    Google Scholar 

  10. Cassidy JT, Sullivan DB, Petty RE. Clinical patterns of chronic iridocyclitis in children with juvenile rheumatoid arthritis. Arthritis Rheum. 1977;20(2 Suppl):224–7.

    CAS  Google Scholar 

  11. Angeles-Han ST, McCracken C, Yeh S, Jang SR, Jenkins K, Cope S, et al. HLA associations in a cohort of children with juvenile idiopathic arthritis with and without uveitis. Invest Ophthalmol Vis Sci. 2015;56:6043–8.

    CAS  Google Scholar 

  12. Prahalad S, Thompson SD, Conneely KN, Jiang Y, Leong T, Prozonic J, et al. Hierarchy of risk of childhood-onset rheumatoid arthritis conferred by HLA-DRB1 alleles encoding the shared epitope. Arthritis Rheum. 2012;64:925–30.

    CAS  Google Scholar 

  13. Rosenbaum JT. New developments in uveitis associated with HLA B27. Curr Opin Rheumatol. 2017;29:298–303.

    CAS  Google Scholar 

  14. Angeles-Han ST, McCracken C, Yeh S, Jenkins K, Stryker D, Rouster-Stevens K, et al. Characteristics of a cohort of children with juvenile idiopathic arthritis and JIA-associated uveitis. Pediatr Rheumatol Online J. 2015;13:19.

    Google Scholar 

  15. Kamal S, Kumar R, Kumar S, Goel R. Bilateral interstitial keratitis and granulomatous uveitis of tubercular origin. Eye Contact Lens. 2014;40:e13–5.

    Google Scholar 

  16. Clarke SL, Sen ES, Ramanan AV. Juvenile idiopathic arthritis-associated uveitis. Pediatr Rheumatol Online J. 2016;14:27.

    Google Scholar 

  17. Cunningham EJ, Rathinam SR, Tugal-Tutkun I, Muccioli C, Zierhut M. Vogt-Koyanagi-Harada disease. Ocul Immunol Inflamm. 2014;22:249–52.

    Google Scholar 

  18. Wouters CH, Maes A, Foley KP, Bertin J, Rose CD. Blau syndrome, the prototypic auto-inflammatory granulomatous disease. Pediatr Rheumatol Online J. 2014;12:33.

    Google Scholar 

  19. Burke MJ, Rennebohm RM. Eye involvement in Kawasaki disease. J Pediatr Ophthalmol Strabismus. 1981;18:7–11.

    CAS  Google Scholar 

  20. Abu Samra K, Maghsoudlou A, Roohipoor R, Valdes-Navarro M, Lee S, Foster CS. Current treatment modalities of JIA-associated uveitis and its complications: literature review. Ocul Immunol Inflamm. 2016;24:431–9.

    Google Scholar 

  21. Kump LI, Castañeda RA, Androudi SN, Reed GF, Foster CS. Visual outcomes in children with juvenile idiopathic arthritis-associated uveitis. Ophthalmology. 2006;113:1874–7.

    Google Scholar 

  22. Thorne JE, Woreta FA, Dunn JP, Jabs DA. Risk of cataract development among children with juvenile idiopathic arthritis-related uveitis treated with topical corticosteroids. Ophthalmology. 2010;117:1436–41.

    Google Scholar 

  23. Cann M, Ramanan AV, Crawford A, Dick AD, Clarke SLN, Rashed F, et al. Outcomes of non-infectious paediatric uveitis in the era of biologic therapy. Pediatr Rheumatol Online J. 2018;16:51.

    Google Scholar 

  24. Carvounis PE, Herman DC, Cha S, Burke JP. Incidence and outcomes of uveitis in juvenile rheumatoid arthritis, a synthesis of the literature. Graefes Arch Clin Exp Ophthalmol. 2006;244:281–90.

    Google Scholar 

  25. Jabs DA, Nussenblatt RB, Rosenbaum JT, Standardization of Uveitis Nomenclature (SUN) Working Group. Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol. 2005;140:509–16.

    Google Scholar 

  26. Angeles-Han ST, Ringold S, Beukelman T, Lovell D, Cuello CA, Becker ML, et al. 2019 American college of rheumatology/arthritis foundation guideline for the screening, monitoring, and treatment of juvenile idiopathic arthritis-associated uveitis. Arthritis Care Res (Hoboken). 2019;71:703–16.

    Google Scholar 

  27. Constantin T, Foeldvari I, Anton J, de Boer J, Czitrom-Guillaume S, Edelsten C, et al. Consensus-based recommendations for the management of uveitis associated with juvenile idiopathic arthritis: the SHARE initiative. Ann Rheum Dis. 2018;77:1107–17.

    Google Scholar 

  28. Yasumura J, Yashiro M, Okamoto N, Shabana K, Umebayashi H, Iwata N, et al. Clinical features and characteristics of uveitis associated with juvenile idiopathic arthritis in Japan: first report of the pediatric rheumatology association of Japan (PRAJ). Pediatr Rheumatol Online J. 2019;17:15.

    Google Scholar 

  29. Dick AD, Rosenbaum JT, Al-Dhibi HA, Belfort R Jr, Brézin AP, Chee SP, et al. Guidance on noncorticosteroid systemic immunomodulatory therapy in noninfectious uveitis: fundamentals of care for uveitis (FOCUS) initiative. Ophthalmology. 2018;125:757–73.

    Google Scholar 

  30. Foeldvari I, Nielsen S, Kümmerle-Deschner J, Espada G, Horneff G, Bica B, et al. Tumor necrosis factor-alpha blocker in treatment of juvenile idiopathic arthritis-associated uveitis refractory to second-line agents: results of a multinational survey. J Rheumatol. 2007;34:1146–50.

    CAS  Google Scholar 

  31. García-De-Vicuña C, Díaz-Llopis M, Salom D, Bou R, Díaz-Cascajosa J, Cordero-Coma M, et al. Usefulness of adalimumab in the treatment of refractory uveitis associated with juvenile idiopathic arthritis. Mediators Inflamm. 2013;2013:560632.

    Google Scholar 

  32. Kolomeyer AM, Tu Y, Miserocchi E, Ranjan M, Davidow A, Chu DS. Chronic non-infectious uveitis in patients with juvenile idiopathic arthritis. Ocul Immunol Inflamm. 2016;24:377–85.

    CAS  Google Scholar 

  33. Sobrin L, Christen W, Foster CS. Mycophenolate mofetil after methotrexate failure or intolerance in the treatment of scleritis and uveitis. Ophthalmology. 2008;115:1416–21.

    Google Scholar 

  34. Gueudry J, Touhami S, Quartier P, Bodaghi B. Therapeutic advances in juvenile idiopathic arthritis—associated uveitis. Curr Opin Ophthalmol. 2019;30:179–86.

    Google Scholar 

  35. Kalinina Ayuso V, Ten Cate HA, van der Does P, Rothova A, de Boer JH. Male gender and poor visual outcome in uveitis associated with juvenile idiopathic arthritis. Am J Ophthalmol. 2010;149:987–93.

    Google Scholar 

  36. Vitale AT, Graham E, de Boer JH. Juvenile idiopathic arthritis-associated uveitis: clinical features and complications, risk factors for severe course, and visual outcome. Ocul Immunol Inflamm. 2013;21:478–85.

    Google Scholar 

Download references

Acknowledgement

We wish to thank Prof. Mei-Ping Lu (Children’s Hospital, Zhejiang University School of Medicine) and Prof. Lawrence K. Jung (emeritus professor of Pediatrics George Washington University) for their support.

Funding

None.

Author information

Authors and Affiliations

  1. Division of Rheumatology, Department of Pediatrics, University of British Columbia, 4480 Oak Street, Vancouver, BC, V6H 3V4, Canada

    Ross E. Petty

  2. Department of Rheumatology Immunology and Allergy, Children’s Hospital, Zhejiang University School of Medicine, 57# Zhu Gan Road Zhejiang Province, Hangzhou, 310000, China

    Qi Zheng

Authors
  1. Ross E. Petty
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Qi Zheng
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

Both authors contributed equally to the manuscript. The authors approved the final version of the manuscript.

Corresponding author

Correspondence to Ross E. Petty.

Ethics declarations

Ethical approval

Not required.

Conflict of interest

No financial or nonfinancial benefits have been received or will be received from any party related directly or indirectly to the subject of this article.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Petty, R.E., Zheng, Q. Uveitis in juvenile idiopathic arthritis. World J Pediatr 16, 562–565 (2020). https://doi.org/10.1007/s12519-019-00331-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12519-019-00331-6

Search

Navigation