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Immunoglobulin G4-related hepatic inflammatory pseudotumor invading the abdominal wall

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Abstract

A 50-year-old woman presented with epigastralgia. Computed tomography (CT) of the abdomen revealed a 6-cm well-enhanced mass extending from the left lobe of the liver to the abdominal wall, suggestive of cholangiocarcinoma. Liver and skin mass biopsies did not provide evidence of hepatic malignancy but were rich in plasma cells and sclerotic lesions. Subsequent detection of elevated serum immunoglobulin G4 (IgG4) led to a diagnosis IgG4-related inflammatory pseudotumor (IPT) of the liver. Treatment with systemic corticosteroids resulted in rapid clinical improvement. This case is the first report of an IgG4-related hepatic IPT invading the abdominal wall.

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Acknowledgements

I thank Kumi Fujita, Pathological Department of Tenri Hospital and Mizue Yamamoto, Dermatology Department of Chiba University for contributing useful comments on the draft version.

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Authors and Affiliations

  1. Gastroenterology, Tenri Hospital, 200 Mishima-chou, Tenri, Nara Prefecture, Japan

    Shinji Miyajima, Akihiro Okano & Masaya Ohana

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  1. Shinji Miyajima
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  2. Akihiro Okano
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  3. Masaya Ohana
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Correspondence to Shinji Miyajima.

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Conflict of interest:

Shinji Miyajima, Akihiro Okano and Masaya Ohana declare that they have no conflict of interest.

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All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

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Informed consent was obtained from all patients for being included in the study.

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Miyajima, S., Okano, A. & Ohana, M. Immunoglobulin G4-related hepatic inflammatory pseudotumor invading the abdominal wall. Clin J Gastroenterol 10, 57–62 (2017). https://doi.org/10.1007/s12328-016-0701-4

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  • DOI: https://doi.org/10.1007/s12328-016-0701-4

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