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Is There a Role for Neoadjuvant Chemotherapy Without Radiotherapy in Locally Advanced Rectal Cancer?

  • Localized Rectal Cancer (R Glynne-Jones, Section Editor)
  • Published:
Current Colorectal Cancer Reports

Abstract

The treatment paradigm for locally advanced rectal cancer is multidisciplinary and includes chemoradiotherapy and surgery followed by adjuvant chemotherapy. This review discusses the rationale behind multimodality treatment, the role of radiotherapy, and the potential for its omission in selected patients in the future.

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Conflict of Interest

Andrea Cercek declares she has no conflict of interest.

Karyn A. Goodman declare she has no conflict of interest.

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Authors and Affiliations

  1. Department of Medicine, Memorial Sloan-Kettering Cancer Center, 410 E. 68th Street, New York, NY, 10065, USA

    Andrea Cercek

  2. Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA

    Karyn A. Goodman

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  1. Andrea Cercek
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  2. Karyn A. Goodman
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Correspondence to Andrea Cercek.

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Cercek, A., Goodman, K.A. Is There a Role for Neoadjuvant Chemotherapy Without Radiotherapy in Locally Advanced Rectal Cancer?. Curr Colorectal Cancer Rep 9, 126–129 (2013). https://doi.org/10.1007/s11888-013-0171-8

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  • DOI: https://doi.org/10.1007/s11888-013-0171-8

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