Abstract
Purpose
The purpose of this study was to map the distribution of 2-deoxy-2-[18F]fluoro-d-glucose (FDG) uptake in organs of patients with no known abnormalities in those tissues.
Procedures
We measured maximum and mean standardized uptake values (SUV) from FDG-positron emission tomography (PET)/computed tomography (CT) obtained from 98 patients (48 males and 50 females).
Results
Significant uptake (mean SUVmean > 2.5) was visualized in the cerebellum (8.0 ± 2.2), soft palate (2.92 ± 0.86), palatine tonsils (3.45 ± 1.4), lingual tonsils (3.08 ± 1.05), sublingual glands (3.3 ± 1.5), and testes (2.57 ± 0.56). Negative correlation for FDG uptake versus age was observed for the palatine tonsils, sublingual glands, and lungs (P < 0.001).
Conclusion
Better understanding of physiological uptake throughout the body is valuable for improved interpretive accuracy and should be useful for future semi-automated comparisons to a normal SUV database.
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Wang, Y., Chiu, E., Rosenberg, J. et al. Standardized Uptake Value Atlas: Characterization of Physiological 2-Deoxy-2-[18F]fluoro-d-glucose Uptake in Normal Tissues. Mol Imaging Biol 9, 83–90 (2007). https://doi.org/10.1007/s11307-006-0075-y
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DOI: https://doi.org/10.1007/s11307-006-0075-y