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Low- to moderate-grade myxoid chondrosarcoma in the craniofacial region: CT and MRI findings in 13 cases

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Abstract

Objectives

To identify the imaging features of low- to moderate-grade myxoid chondrosarcomas (MCs) in the craniofacial region.

Methods

The imaging features of 13 patients with MCs in the craniofacial region were retrospectively reviewed. Computed tomography (CT) scanning was performed in 4 patients and magnetic resonance imaging (MRI) was performed in 5 patients. The remaining four patients underwent both CT and MRI examinations.

Results

Of the 13 MCs, 7 were located in the intracranial region and 6 were located in the maxillofacial region. The lesions showed low density on CT images in all eight patients with CT scans. Four patients had isointense signals and five patients had hypointense signals on T1-weighted MR images. Eight patients had hyperintense signals on T2-weighted MR images. Calcification was found in six patients, including three patients with typical “ring-and-arc” chondroid calcification. Typical lobular architecture of the cartilage was found in six of nine patients with MRI examinations. The high-signal intensity non-enhanced areas on MRI corresponded to the areas showing hyaline cartilage on histological examination.

Conclusion

Low- to moderate-grade craniofacial MCs had distinctive imaging features. Knowledge of their imaging features would be helpful for improving preoperative diagnosis and planning clinical management.

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Conflict of interest

Huijun Hu, Xiaomao Xu, Weike Zeng, Hong Deng, Dandan Yun, and Guozhao Li declare that they have no conflict of interest.

Human rights statements and informed consent

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (Sun Yat-Sen University, China) and with the Helsinki Declaration of 1964 and later versions. Informed consent was not required in accordance with the requirements of our university for such a retrospective study.

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Correspondence to Guozhao Li.

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Hu, H., Xu, X., Zeng, W. et al. Low- to moderate-grade myxoid chondrosarcoma in the craniofacial region: CT and MRI findings in 13 cases. Oral Radiol 31, 81–89 (2015). https://doi.org/10.1007/s11282-014-0184-2

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  • DOI: https://doi.org/10.1007/s11282-014-0184-2

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