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The impact of periodontal disease on physical and psychological domains in long-term hemodialysis patients: a cross-sectional study

  • Nephrology – Original Paper
  • Published:
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Abstract

Purpose

Periodontal disease is a chronic infectious disease. Individuals with end-stage kidney disease (ESKD) experience impaired quality of life (QoL) and low oral health. This is the first comprehensive study which aimed to explore the link between periodontal disease and quality of life, assessed with the Short Form 36-Item Health Survey in hemodialysis patients.

Methods

In total, 101 patients (57 females) with ESKD were recruited from two Romanian dialysis centers. Periodontal disease assessment included the measurement of periodontal disease index, with its three components: the gingival and periodontal index (GP), the bacterial plaque index (PI) and the calculus index (CI). For assessing QoL, we used the Short Form 36-Item Health Survey (SF-36), with its two components: physical component (PCS) and mental component (MCS).

Results

The mean age was 52.5 ± 14.3 years. The dialysis vintage was 6.7 ± 5.6 years. According to periodontal status, the mean value of GP was 4.0 ± 1.3, mean PI was 1.8 ± 0.9, and mean CI was 1.3 ± 0.7. Regarding the QoL, the means for PCS and MCS were 38.0 ± 17.3 and 45.0 ± 16.3, respectively. In univariate analysis, the physical and mental components of QoL were significantly associated with the gingival and periodontal index, the bacterial plaque index and the calculus index. In the multivariable linear regression, only the gingival and periodontal index remained significantly associated with physical component (β = −3.26, p = 0.04, 95% CI −6.39 to −0.13) and mental component (β = −5.57, p = 0.001, 95% CI −8.74 to −2.41) of QoL.

Conclusion

Our study shows a high prevalence and severity of periodontal disease. The gingival and periodontal index was associated with low QoL, both on physical and on mental components.

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Acknowledgements

This paper was published under the frame of European Social Found, Human Resources Development Operational Programme 2007–2013, project no. POSDRU/159/1.5/136893 and by the University of Medicine and Pharmacy “Gr. T. Popa,” Iasi (Grants No. 29235/01.01.2014).

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    Authors and Affiliations

    1. Nephrology Department, Faculty of Medicine, University of Medicine and Pharmacy “Gr. T. Popa”, Iasi, Romania

      Gabriel Veisa, Ionut Nistor, Liviu Segall, Dimitrie Siriopol, Mihaela Dora Donciu, Luminita Voroneanu, Andra Nastasa & Adrian Covic

    2. Dialysis and Renal Transplantation Center, “Dr. C. I. Parhon” University Hospital, Iasi, Romania

      Alexandra Tasmoc

    3. Medical Deontology and Bioethics Department, Faculty of Medicine, University of Medicine and Pharmacy “Gr. T. Popa”, Iasi, Romania

      Alexandra Tasmoc

    4. Periodontology Department, Faculty of Dental Medicine, University of Medicine and Pharmacy “Gr. T. Popa”, Iasi, Romania

      Sorina Mihaela Solomon

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    1. Gabriel Veisa
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    Correspondence to Alexandra Tasmoc.

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    The authors declare that they have no conflict of interest.

    Ethical approval

    The study was approved by the Hospital’s Ethical Committee and was performed in agreement with Helsinki’s declaration of human rights.

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    Informed consent was obtained from all individual participants included in the study.

    Additional information

    Gabriel Veisa and Alexandra Tasmoc have contributed equally to this work.

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    Veisa, G., Tasmoc, A., Nistor, I. et al. The impact of periodontal disease on physical and psychological domains in long-term hemodialysis patients: a cross-sectional study. Int Urol Nephrol 49, 1261–1266 (2017). https://doi.org/10.1007/s11255-017-1571-5

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