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A tale of pituitary adenomas: to NET or not to NET

Pituitary Society position statement

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References

  1. WHO (2004) Pathology and genetics of tumours of endocrine organs. WHO classification of tumours, vol 8, 3 edn. WHO Press, Geneva

  2. WHO (2017) WHO classification of tumours of endocrine organs. WHO classification of tumours, vol 10, 4 edn. WHO Press, Geneva

  3. Asa SL, Casar-Borota O, Chanson P, Delgrange E, Earls P, Ezzat S, Grossman A, Ikeda H, Inoshita N, Karavitaki N, Korbonits M, Laws ER Jr, Lopes MB, Maartens N, McCutcheon IE, Mete O, Nishioka H, Raverot G, Roncaroli F, Saeger W, Syro LV, Vasiljevic A, Villa C, Wierinckx A, Trouillas J (2017) From pituitary adenoma to pituitary neuroendocrine tumor (PitNET): an International Pituitary Pathology Club proposal. Endocr Relat Cancer 24(4):C5–c8. https://doi.org/10.1530/erc-17-0004

    Article  CAS  PubMed  Google Scholar 

  4. Rindi G, Klimstra DS, Abedi-Ardekani B, Asa SL, Bosman FT, Brambilla E, Busam KJ, de Krijger RR, Dietel M, El-Naggar AK, Fernandez-Cuesta L, Kloppel G, McCluggage WG, Moch H, Ohgaki H, Rakha EA, Reed NS, Rous BA, Sasano H, Scarpa A, Scoazec JY, Travis WD, Tallini G, Trouillas J, van Krieken JH, Cree IA (2018) A common classification framework for neuroendocrine neoplasms: an International Agency for Research on Cancer (IARC) and World Health Organization (WHO) Expert Consensus proposal. Mod Pathol 31(12):1770–1786. https://doi.org/10.1038/s41379-018-0110-y

    Article  PubMed  PubMed Central  Google Scholar 

  5. Solcia E, Kloppel G, Sobin LH (2000) Histological typing of endocrine tumours. World Health Organization international histological classification of tumours, 2nd edn. Springer, Berlin

    Book  Google Scholar 

  6. Kaltsas GA, Besser GM, Grossman AB (2004) The diagnosis and medical management of advanced neuroendocrine tumors. Endocr Rev 25(3):458–511. https://doi.org/10.1210/er.2003-0014

    Article  CAS  PubMed  Google Scholar 

  7. Molitch ME (2017) Diagnosis and treatment of pituitary adenomas: a review. JAMA 317(5):516–524. https://doi.org/10.1001/jama.2016.19699

    Article  PubMed  Google Scholar 

  8. Chambers EF, Turski PA, LaMasters D, Newton TH (1982) Regions of low density in the contrast-enhanced pituitary gland: normal and pathologic processes. Radiology 144(1):109–113. https://doi.org/10.1148/radiology.144.1.7089241

    Article  CAS  PubMed  Google Scholar 

  9. Wolpert SM, Molitch ME, Goldman JA, Wood JB (1984) Size, shape, and appearance of the normal female pituitary gland. Am J Roentgenol 143(2):377–381. https://doi.org/10.2214/ajr.143.2.377

    Article  CAS  Google Scholar 

  10. Hall WA, Luciano MG, Doppman JL, Patronas NJ, Oldfield EH (1994) Pituitary magnetic resonance imaging in normal human volunteers: occult adenomas in the general population. Ann Intern Med 120(10):817–820. https://doi.org/10.7326/0003-4819-120-10-199405150-00001

    Article  CAS  PubMed  Google Scholar 

  11. Chong BW, Kucharczyk W, Singer W, George S (1994) Pituitary gland MR: a comparative study of healthy volunteers and patients with microadenomas. Am J Neuroradiol 15(4):675–679

    CAS  PubMed  PubMed Central  Google Scholar 

  12. Daly AF, Rixhon M, Adam C, Dempegioti A, Tichomirowa MA, Beckers A (2006) High prevalence of pituitary adenomas: a cross-sectional study in the Province of Liege, Belgium. J Clin Endocrinol Metab 91(12):4769–4775. https://doi.org/10.1210/jc.2006-1668

    Article  CAS  PubMed  Google Scholar 

  13. Fernandez A, Karavitaki N, Wass JA (2010) Prevalence of pituitary adenomas: a community-based, cross-sectional study in Banbury (Oxfordshire, UK). Clin Endocrinol (Oxf) 72(3):377–382. https://doi.org/10.1111/j.1365-2265.2009.03667.x

    Article  Google Scholar 

  14. Agustsson TT, Baldvinsdottir T, Jonasson JG, Olafsdottir E, Steinthorsdottir V, Sigurdsson G, Thorsson AV, Carroll PV, Korbonits M, Benediktsson R (2015) The epidemiology of pituitary adenomas in Iceland, 1955–2012: a nationwide population-based study. Eur J Endocrinol 173(5):655–664. https://doi.org/10.1530/eje-15-0189

    Article  CAS  PubMed  Google Scholar 

  15. Zada G, Woodmansee WW, Ramkissoon S, Amadio J, Nose V, Laws ER Jr (2011) Atypical pituitary adenomas: incidence, clinical characteristics, and implications. J Neurosurg 114(2):336–344. https://doi.org/10.3171/2010.8.Jns10290

    Article  PubMed  Google Scholar 

  16. Scheithauer BW, Gaffey TA, Lloyd RV, Sebo TJ, Kovacs KT, Horvath E, Yapicier O, Young Jr WF, Meyer FB, Kuroki T, Riehle DL, Laws Jr ER (2006) Pathobiology of pituitary adenomas and carcinomas. Neurosurgery 59(2):341–353; discussion 341–353. https://doi.org/10.1227/01.Neu.0000223437.51435.6e

    Article  PubMed  Google Scholar 

  17. Saeger W, Ludecke DK, Buchfelder M, Fahlbusch R, Quabbe HJ, Petersenn S (2007) Pathohistological classification of pituitary tumors: 10 years of experience with the German Pituitary Tumor Registry. Eur J Endocrinol 156(2):203–216. https://doi.org/10.1530/eje.1.02326

    Article  CAS  PubMed  Google Scholar 

  18. Yildirim AE, Divanlioglu D, Nacar OA, Dursun E, Sahinoglu M, Unal T, Belen AD (2013) Incidence, hormonal distribution and postoperative follow up of atypical pituitary adenomas. Turk Neurosurg 23(2):226–231. https://doi.org/10.5137/1019-5149.Jtn.6828-12.1

    Article  PubMed  Google Scholar 

  19. Chiloiro S, Doglietto F, Trapasso B, Iacovazzo D, Giampietro A, Di Nardo F, de Waure C, Lauriola L, Mangiola A, Anile C, Maira G, De Marinis L, Bianchi A (2015) Typical and atypical pituitary adenomas: a single-center analysis of outcome and prognosis. Neuroendocrinology 101(2):143–150. https://doi.org/10.1159/000375448

    Article  CAS  PubMed  Google Scholar 

  20. Melmed S (2011) Pathogenesis of pituitary tumors. Nat Rev Endocrinol 7(5):257–266. https://doi.org/10.1038/nrendo.2011.40

    Article  CAS  PubMed  Google Scholar 

  21. Raverot G, Jouanneau E, Trouillas J (2014) Management of endocrine disease: clinicopathological classification and molecular markers of pituitary tumours for personalized therapeutic strategies. Eur J Endocrinol 170(4):R121–R132. https://doi.org/10.1530/eje-13-1031

    Article  CAS  PubMed  Google Scholar 

  22. Nasi D, Perano D, Ghadirpour R, Iaccarino C, Servadei F, Romano A (2017) Primary pituitary neuroendocrine tumor: case report and literature review. Surg Neurol Int 8:101. https://doi.org/10.4103/sni.sni_450_16

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  23. Liu H, Wang H, Qi X, Yu C (2016) Primary intracranial neuroendocrine tumor: two case reports. World J Surg Oncol 14:138. https://doi.org/10.1186/s12957-016-0887-4

    Article  PubMed  PubMed Central  Google Scholar 

  24. Marx SJ, Nieman LK (2002) Aggressive pituitary tumors in MEN1: do they refute the two-hit model of tumorigenesis? J Clin Endocrinol Metab 87(2):453–456. https://doi.org/10.1210/jcem.87.2.8289

    Article  CAS  PubMed  Google Scholar 

  25. Satoh F, Umemura S, Yasuda M, Osamura RY (2001) Neuroendocrine marker expression in thyroid epithelial tumors. Endocr Pathol 12(3):291–299

    Article  CAS  PubMed  Google Scholar 

  26. Haak HR, Fleuren GJ (1995) Neuroendocrine differentiation of adrenocortical tumors. Cancer 75(3):860–864. https://doi.org/10.1002/1097-0142(19950201)75:3%3c860:aid-cncr2820750318%3e3.0.co;2-g

    Article  CAS  PubMed  Google Scholar 

  27. Casanueva FF, Barkan AL, Buchfelder M, Klibanski A, Laws ER, Loeffler JS, Melmed S, Mortini P, Wass J, Giustina A (2017) Criteria for the definition of Pituitary Tumor Centers of Excellence (PTCOE): a Pituitary Society statement. Pituitary 20(5):489–498. https://doi.org/10.1007/s11102-017-0838-2

    Article  PubMed  PubMed Central  Google Scholar 

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Acknowledgements

This position paper is co-authored by the Editors of PITUITARY and Officers of the Pituitary Society. No external or Society funding supported this work. The authors thank Shira Berman for outstanding editorial assistance.

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Correspondence to Ken K. Y. Ho.

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Ho, K.K.Y., Fleseriu, M., Wass, J. et al. A tale of pituitary adenomas: to NET or not to NET. Pituitary 22, 569–573 (2019). https://doi.org/10.1007/s11102-019-00988-2

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