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Pituitary apoplexy and rivaroxaban

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Abstract

Pituitary apoplexy (PA), defined by the occurrence of a massive hemorrhagic necrotic rearrangement within a pituitary adenoma, is rare. Its occurrence can be associated with certain risk factors, including anticoagulation. We report the first case of PA with rivaroxaban which is one of the new oral anticoagulants: a 73 year-old patient presenting with severe headache and visual field deterioration. Surgery was performed. Radiotherapy treatment was decided three months after surgery because of tumor residue.

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References

  1. Chatterjee S, Sardar P, Biondi-Zoccai G, Kumbhani D (2013) New oral anticoagulants and the risk of intracranial hemorrhage: traditional and Bayesian meta-analysis and mixed treatment comparison of randomized trials of new oral anticoagulants in atrial fibrillation. JAMA Neurol 70(12):1486–1490

    PubMed  Google Scholar 

  2. Connolly SJ, Ezekowitz MD, Yusuf S, Eikelboom J, Oldgren J, Parekh A, Pogue J, Reilly PA, Themeles E, Varrone J, Wang S, Alings M, Xavier D, Zhu J, Diaz R, Lewis BS, Darius H, Diener HC, Joyner CD, Wallentin L (2009) Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 361(12):1139–1151

    Article  CAS  PubMed  Google Scholar 

  3. Uemura M, Miyashita F, Shimomura R, Fujinami J, Toyoda K (2013) Pituitary apoplexy during treatment with dabigatran. Neurol Clin Neurosci 1:82–83

    Article  Google Scholar 

  4. Doglietto F, Costi E, Villaret AB, Mardighian D, Fontanella MM, Giustina A (2016) New oral anticoagulants and pituitary apoplexy. Pituitary 19(2):232‑4

    Article  Google Scholar 

  5. Doglietto F, Roca E, La Rocca G, Schreiber A, Bolzoni Villaret A, Nicolai P et al (2017) New oral anticoagulants and pituitary apoplexy. World Neurosurg 100:700

    Article  PubMed  Google Scholar 

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Correspondence to S. Ly.

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Ly, S., Naman, A., Chaufour-Higel, B. et al. Pituitary apoplexy and rivaroxaban. Pituitary 20, 709–710 (2017). https://doi.org/10.1007/s11102-017-0828-4

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  • DOI: https://doi.org/10.1007/s11102-017-0828-4

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