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DPPH Scavenging Property of Active Principles from Soft Coral Sarcophyton Flexuosum Tixier-Durivault

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Pharmaceutical Chemistry Journal Aims and scope

2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical scavenging capacity of the crude methanolic extract from the soft coral Sarcophyton flexuosum Tixier-Durivault was assayed. The crude methanolic extract of S. flexuosum collected from Lakshadweep Island showed significant potential in antioxidant activity. GC-MS analysis of the hexane and chloroform extracts of S. flexuosum revealed the presence of 27 compounds belonging to five major groups including esters, hydrocarbons, carbonyls, ethers, and alcohols. In these compounds, fatty acid esters were found to be the major chemical group, followed by hydrocarbons, ethers, carbonyls, and alcohols. Among the compounds identified, butyl butyrate, methyl palmitate, methyl (9E)-9-octadecenoate, propanoic acid butyl ester, undecane, 2-ethyl-hexan-1-ol and isosteviol were found to be pharmacologically important, based on their reported activity.

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References

  1. A. M. S Mayer, and V. K. B Lehmann, Pharmacologist, 42, 62 – 69 (2000).

  2. J. W. Blunt, R. Brent, C. Robert, et al., Natur. Prod. Rep., 28, 196 (2011).

    Article  CAS  Google Scholar 

  3. D. J. Faulkner., Natur. Prod. Rep., 19, 1 – 43 (2002).

  4. D. J. Faulkner and W. Fenical, Tetrahedron, 33, 1421 – 1443 (1977).

    Article  CAS  Google Scholar 

  5. Y. Benayahu, and Y. Loya, Helgolander wiss. Meeresunters., 30, 362 – 382 (1977).

    Article  Google Scholar 

  6. Y. Neeman, L. Fishelson, and Y. Kashman, Toxicon, 12, 593 – 598 (1974).

    Article  CAS  Google Scholar 

  7. J. C. Coll., Chem. Rev., 92, 613 – 631 (1992).

  8. O. Yamauchi, M. Omori, M. Ninomiya, et al., Jpn. J. Cancer Res., 82, 1234 – 1238 (1991).

    Article  CAS  PubMed  Google Scholar 

  9. F. A. Badria, A. N. Guirguis, and W. A. El-Naggar, Int. J. Pharm., 5, 284 – 287 (1997).

    Article  Google Scholar 

  10. C. Y. Wang, M. Y. Geng, and H. S. Guan, Chin. J. New Drugs, 14, 278 – 282 (2005).

    Google Scholar 

  11. G. W. Zhang, X. Q. Ma, H. Kurihara, et al., Org. Lett., 7(6), 991 – 994 (2005).

    Article  CAS  PubMed  Google Scholar 

  12. A. Prakash, F. Rigelhof, and E. Miller, Medallion Laboratories: Analytical progress.

  13. Kriengsak Thaipong, et al., J. Food Compos. Anal., 19, 669 – 675 (2006).

  14. http: // www.pesticideinfo.org / Detail Chemical.jsp?Rec Id= PC42007

  15. P. S. Praveen Kumar, S. Kumaravel, and C. Lalitha, Afr. J. Biochem. Res., 4, 191 – 195 (2010).

    CAS  Google Scholar 

  16. F. R. Yu, X. Z. Lian, H. Y. Guo, et al., J. Pharm. Sci., 3, 528 – 535 (2005).

    Google Scholar 

  17. O. G. Mironov, T. L. Shchekaturina, and I. M. Tsimbal., Marine Ecol. Prog. Ser., 5, 303 – 309 (1981).

  18. Y. S. Yoo, J. Osaka City Med. Center, 34, 267 – 288 (1986).

    Google Scholar 

  19. European Commission (2002): Opinion of the Scientific Committee on Food on the Presence of Hypericin and Extracts of Hypericum Sp. in Flavorings and Other Food Ingredients with Flavoring Properties. SCF / CS / FLAV / FLAVOUR / 5 ADD1 Retrieved from http: // europa.eu.int / comm / food / fs / sc / scf / out113 en.pdf

  20. B. L. Van Durren and B. M. Goldschmidt, J. Natl. Cancer Inst., 56, 1237 – 1242 (1976).

    Google Scholar 

  21. http: // www.thegoodscentscompany.com / data / rw1573931.html

  22. Hazardous Substances Data Bank, Toxicology and Environmental Health Information Program, National Library of Medicine, Bethesda, MD (2004), retrieved from http: // toxnet.nlm. nih.gov / cgibin / sis / htmlgen?HSDB

  23. Toxicological Evaluation of Certain Food Additives and Contaminants, WHO Food Additives Series, No. 32, Prepared by the 41st Meeting of the Joint FAO / WHO Expert Committee on Food Additives (JEFCA), WHO, Geneva (1993). ISBN: 92 – 4 – 166032 – 5, retrieved from http: // www.inchem.org / documents / jecfa / jecmono / v32je04.htm.

  24. R. A. Scala and E. G. Burtis, Am. Ind. Hygiene Assoc. J., 34, 493 – 499 (1973).

    Article  CAS  Google Scholar 

  25. http: // www.thegoodscentscompany.com / data / rw1590941.html

  26. http: // www.thegoodscentscompany.com / data / rw1026181.html

  27. E. Mosetting and W. R. Nes, J. Org. Chem., 20, 884 – 899 (1955).

    Google Scholar 

  28. V. A. Al’fonsov, G. A. Bakaleinik, A. T. Gubaidullin, et al., Russ. J. Gen. Chem., 68, 1735 – 1743 (1998).

    Google Scholar 

  29. R. Z. Musin, V. M. Babaev, I. Yu. Strobykina, et al., Russ. J. Gen. Chem., 79, 2377 – 2382 (2009).

    Article  CAS  Google Scholar 

  30. Deyi Xu, Wenfeng Du, Lei Zhao, et al., Planta Med., 74, 816 – 821 (2008).

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Acknowledgments

Authors thank Dr. P. A Thomas for his helped in the taxonomic identification of the organism S. flexuosum Tixier-Durivault. The financial support received from the Government of Kerala to establish a new centre, Inter University Centre for the Development of Marine Biotechnology (IUCDMB) is gratefully acknowledged.

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Authors and Affiliations

  1. Inter University Center for Development of Marine Biotechnology (IUCDMB), Cochin University of Science and Technology, Cochin, India

    K. Byju, V. Anuradha, Emilda Rosmine, H. S. Hari Sankar, K. J. Prashob Peter, T. R. Gireesh Kumar, G. Vasundhara, N. C. Kumar & S. M. Nair

  2. Department of Chemistrycsm, St. Teresas College, Cochin, India

    Anu Gopinath

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  1. K. Byju
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  2. V. Anuradha
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  3. Emilda Rosmine
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Correspondence to S. M. Nair.

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Byju, K., Anuradha, V., Rosmine, E. et al. DPPH Scavenging Property of Active Principles from Soft Coral Sarcophyton Flexuosum Tixier-Durivault. Pharm Chem J 49, 178–182 (2015). https://doi.org/10.1007/s11094-015-1249-1

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  • DOI: https://doi.org/10.1007/s11094-015-1249-1

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