Abstract
Hepatic encephalopathy (HE) is characterized by a wide variety of neuropsychiatric symptoms, and from a psychiatric perspective its nosological status calls for clarification. According to the ICD-10 classification, it can be classified as delirium due to overt HE´s core symptom of clouding of consciousness in increasing degrees. Minimal/covert HE with impairment of neurocognitive function is more difficult to classify and could correspond to Mild Cognitive Impairment or mild degrees of dementia. However, the advantages of current psychiatric nosology is the possibility of thorough characterization of both dispositional and premorbid psychopathology as well as psychiatric morbidity induced by liverdiseases or even treatment. A future closer collaboration between hepatologists and psychiatrists is advocated.
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References
Prakash R, Mullen KD (2010) Mechanisms, diagnosis and management of hepatic encephalopathy. Nat Rev Gastroenterol Hepatol 7(9):515–525
Rivera Ramos JF, Rodriguez Leal C (2011) Review of the final report of the 1998 Working Party on definition, nomenclature and diagnosis of hepatic encephalopathy. Ann Hepatol 10(Suppl 2):S36–S39
Randolph C, Hilsabeck R, Kato A, Kharbanda P, Li YY, Mapelli D et al (2009) Neuropsychological assessment of hepatic encephalopathy: ISHEN practice guidelines. Liver Int 29(5):629–635
Cordoba J (2011) New assessment of hepatic encephalopathy. J Hepatol 54(5):1030–1040
Weissenborn K, Ennen JC, Schomerus H, Ruckert N, Hecker H (2001) Neuropsychological characterization of hepatic encephalopathy. J Hepatol 34(5):768–773
Kappus MR, Bajaj JS (2012) Covert hepatic encephalopathy: Not as minimal as you might think. Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association
World Health Organization (1992) The ICD-10 Classification of Mental and Behavioural Disorders. World Health Organization, Geneva, pp 1–362
American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders. American Psychiatric Association, Washington, pp 1–886
Sperling RA, Aisen PS, Beckett LA, Bennett DA, Craft S, Fagan AM et al (2011) Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7(3):280–292
Dwight MM, Kowdley KV, Russo JE, Ciechanowski PS, Larson AM, Katon WJ (2000) Depression, fatigue, and functional disability in patients with chronic hepatitis C. J Psychosom Res 49(5):311–317
Schaefer M, Hinzpeter A, Mohmand A, Janssen G, Pich M, Schwaiger M et al (2007) Hepatitis C treatment in “difficult-to-treat” psychiatric patients with pegylated interferon-alpha and ribavirin: response and psychiatric side effects. Hepatology 46(4):991–998
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Rosenberg, R., Renvillard, S.G. & Hjerrild, S. Organic delirious states and other psychiatric disorders: lessons for the hepatologists. Metab Brain Dis 28, 235–238 (2013). https://doi.org/10.1007/s11011-012-9340-8
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DOI: https://doi.org/10.1007/s11011-012-9340-8