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Multifactorial inheritance with selection

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Abstract

We present an alternative model for multifactorial inheritance. By changing the way the malformation (and selection) is determined from the genetic information, we arrive at a model that can be properly handled in the mathematical sense. This includes the proof of population convergence and computation of conditional malformation probabilities in a closed form. We also present a comparison to similar models and results of fitting our model to Hungarian data.

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Authors and Affiliations

  1. Alfréd Rényi Institute of Mathematics, Hungarian Academy of Sciences, H-1364, Budapest, Pf. 127, Hungary

    Balázs Gerencsér & Gábor Tusnády

  2. ETH Zürich, Zürich, Switzerland

    Balázs Ráth

Authors
  1. Balázs Gerencsér
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  2. Balázs Ráth
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  3. Gábor Tusnády
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Correspondence to Balázs Gerencsér.

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Gerencsér, B., Ráth, B. & Tusnády, G. Multifactorial inheritance with selection. Acta Math Hung 139, 160–182 (2013). https://doi.org/10.1007/s10474-012-0248-x

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  • DOI: https://doi.org/10.1007/s10474-012-0248-x

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