Abstract
Studies investigating dental arch spatial changes following first primary molar premature loss are controversial regarding clinical significance. The purpose of this review was to systematically investigate the relevant literature. Controlled studies investigating changes before and after premature loss of first primary molars were searched in various databases. Split-mouth design studies were considered eligible for inclusion. The risk of bias was judged according to ADA Clinical Practice Guidelines. Only two analyzable split-mouth studies on mandibular first primary molar loss were identified. Space loss in the extraction side was greater at 2, 4, 6 and 8-month follow-ups, reaching a −1.5 mm difference in the final examination (95% Confidence Interval: −2.080 to −0.925; p = 0.000; random effects model). Studies were judged to be at unclear risk of bias. The amount of space decrease after premature loss of first primary molars may have management implications under certain circumstances. Comprehensive assessment of the various characteristics of each patient should precede management decisions in individual cases.
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References
Petersen PE. The World Oral Health Report 2003: continuous improvement of oral health in the 21st century—the approach of the WHO Global Oral Health Programme. Community Dent Oral Epidemiol. 2003;31(Suppl 1):3–23.
Mitchell L. An introduction to orthodontics. New York: Oxford University Press Inc.; 2007.
Proffit WR, Fields HW, Sarver DM. Contemporary Orthodontics. 5th ed. St Louis: Mosby; 2013.
Miyamoto W, Chung CS, Yee PK. Effect of premature loss of deciduous canines and molars on malocclusion of the permanent dentition. J Dent Res. 1976;55:584–90.
Kisling E, Høffding J. Premature loss of primary teeth: part V, treatment planning with due respect to the significance of drifting patterns. ASDC J Dent Child. 1979;46:300–6.
Pedersen J, Stensgaard K, Melsen B. Prevalence of malocclusion in relation to premature loss of primary teeth. Community Dent Oral Epidemiol. 1978;6:204–9.
Melsen B, Terp S. The influence of extractions caries cause on the development of malocclusion and need for orthodontic treatment. Swed Dent J Suppl. 1982;15:163–9.
Northway WM, Wainright RL, Demirjian A. Effects of premature loss of deciduous molars. Angle Orthod. 1984;54:295–329.
Northway WM. The not-so-harmless maxillary primary first molar extraction. J Am Dent Assoc. 2000;131:1711–20.
Bhujel N, Duggal M, Munyombwe T, Godson J, Day P. The effect of premature extraction of primary teeth on the subsequent need for orthodontic treatment. Eur Arch Paediatr Dent. 2014;15:393–400.
American Academy of Pediatric Dentistry. Guideline on management of the developing dentition and occlusion in pediatric dentistry. Clinical Affairs Committee—Developing Dentition Subcommittee. Pediatr Dent. 2015;37(Suppl):253–65.
Royal College of Surgeons of England. Extraction of primary teeth—balance and compensation. Faculty of Dental Surgery Working Party. 2006. https://www.rcseng.ac.uk/fds/publications-clinical-guidelines/clinical_guidelines/docu ments/extractp.pdf. Accessed 31 Dec 2015.
Rönnerman A. The effect of early loss of primary molars on tooth eruption and space conditions. A longitudinal study. Acta Odontol Scand. 1977;35:229–39.
Kisling E, Høffding J. Premature loss of primary teeth: part III, drifting patterns for different types of teeth after loss of adjoining teeth. ASDC J Dent Child. 1979;46:34–8.
Alnahwi HH, Donly KJ, Contreras CI. Space loss following premature loss of primary second molars. Gen Dent. 2015;63:e1–4.
Rönnerman A, Thilander B. A longitudinal study on the effect of unilateral extraction of primary molars. Scand J Dent Res. 1977;85:362–72.
Johnsen DC. Space observation following loss of the mandibular first primary molars in mixed dentition. ASDC J Dent Child. 1980;47:24–7.
Tunison W, Flores-Mir C, ElBadrawy H, Nassar U, El-Bialy T. Dental arch space changes following premature loss of primary first molars: a systematic review. Pediatr Dent. 2008;30:297–302.
Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. Open Med. 2009;3:123–30.
Higgins JPT, Green S. Cochrane Handbook for Systematic Reviews of Interventions version 5.1.0 [updated March 2011]. The Cochrane Collaboration; 2011. www.cochrane-handbook.org. Accessed 31 Dec 2015.
American Dental Association. ADA Clinical practice guideline handbook: 2013 update. Chicago: American Dental Association; 2013. http://ebd.ada.org/~/media/EBD/Files/ADA_Clinical_Practice_Guidelines_Handbook-2013.ashx. Accessed 31 Dec 2015.
Becker HM, Glass RL, Shiere FR. Exfoliation of the deciduous teeth during the ages of mixed dentition. J Dent Res. 1972;51:498–502.
Macena MC, Tornisiello Katz CR, Heimer MV, de Oliveira e Silvade JF, Costa LB. Space changes after premature loss of deciduous molars among Brazilian children. Am J Orthod Dentofac Orthop. 2011;140:771–8.
Cuoghi OA, Bertoz FA, de Mendonca MR, Santos EC. Loss of space and dental arch length after the loss of the lower first primary molar: a longitudinal study. J Clin Pediatr Dent. 1998;22:117–20.
Owen DG. The incidence and nature of space closure following the premature extraction of deciduous teeth: a literature study. Am J Orthod. 1971;59:37–49.
Lin YT, Lin WH, Lin YT. Twelve-month space changes after premature loss of a primary maxillary first molar. Int J Paediatr Dent. 2011;21:161–6.
Der Simonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7:177–88.
Borenstein M, Hedges L, Rothstein H. Meta-Analysis: Fixed effect vs. random effects. 2007. www.Meta-analysis.com. Accessed 31 Dec 2015.
Ioannidis JP. Interpretation of tests of heterogeneity and bias in metaanalysis. J Eval Clin Pract. 2008;14:951–7.
Lin YT, Chang LC. Space changes after premature loss of the mandibular primary first molar: a longitudinal study. J Clin Pediatr Dent. 1998;22:311–6.
Padma Kumari B, Retnakumari N. Loss of space and changes in the dental arch after premature loss of the lower primary molar: a longitudinal study. J Indian Soc Pedod Prev Dent. 2006;24:90–6.
Ryan R. Cochrane Consumers and Communication Review Group. Cochrane Consumers and Communication Review Group: meta-analysis. 2013. http://cccrg.cochrane.org. Accessed 31 Dec 2015.
Valentine JC, Pigott TD, Rothstein HR. How many studies do you need? A primer on statistical power for meta-analysis. J Educ Behav Stat. 2010;35:215–47.
Coory MD. Comment on: heterogeneity in meta-analysis should be expected and appropriately quantified. Int J Epidemiol. 2010;39:932.
Higgins JP. Commentary: heterogeneity in meta-analysis should be expected and appropriately quantified. Int J Epidemiol. 2008;37:1158–60.
Northway WM, Wainright RW. D E space—a realistic measure of changes in arch morphology: space loss due to unattended caries. J Dent Res. 1980;59:1577–80.
Almeida MA, Phillips C, Kula K, Tulloch C. Stability of the palatal rugae as landmarks for analysis of dental casts. Angle Orthod. 1995;65:43–8.
Bailey LT, Esmailnejad A, Almeida MA. Stability of the palatal rugae as landmarks for analysis of dental casts in extraction and non extraction cases. Angle Orthod. 1996;66:73–8.
Jang I, Tanaka M, Koga Y, Iijima S, Yozgatian JH, Cha BK, Yoshida N. A novel method for the assessment of three-dimensional tooth movement during orthodontic treatment. Angle Orthod. 2009;79:447–53.
Alexander SA, Askari M, Lewis P. The premature loss of primary first molars: space loss to molar occlusal relationships and facial patterns. Angle Orthod. 2015;85:218–23.
Jensen E, Kai-Jen Yen P, Moorrees CF, Thomsen SO. Mesiodistal crown diameters of the deciduous and permanent teeth in individuals. J Dent Res. 1957;36:39–47.
Hixon EH, Oldfather RE. Estimation of the sizes of unerupted cuspid and bicuspid teeth. Angle Orthod. 1958;28:236–40.
Qudeimat MA, Sasa IS. Clinical success and longevity of band and loop compared to crown and loop space maintainers. Eur Arch Paediatr Dent. 2015;16:391–6.
Sasa IS, Hasan AA, Qudeimat MA. Longevity of band and loop space maintainers using glass ionomer cement: a prospective study. Eur Arch Paediatr Dent. 2009;10:6–10.
Tunc ES, Bayrak S, Tuloglu N, Egilmez T, Isci D. Evaluation of survival of 3 different fixed space maintainers. Pediatr Dent. 2012;34:e97–102.
Welbury R, Duggal MS, Hosey M-T. Paediatric dentistry. 4th ed. Oxford: Oxford University Press; 2012.
Laing E, Ashley P, Naini FB, Gill DS. Space maintenance. Int J Paediatr Dent. 2009;19:155–62.
Kocadereli I, Ciger S. Retention of orthodontic bands with three different cements. J Clin Pediatr Dent. 1995;19:127–30.
Enan ET, Hammad SM. Microleakage under orthodontic bands cemented with nano-hydroxyapatite-modified glass ionomer. Angle Orthod. 2013;83:981–6.
Dean JA, Avery Dr, McDonald RE. McDonald and Avery’s Dentistry for the Child and Adolescent (9th ed). Maryland Heights: Mosby; 2011.
Public Health England. Delivering better oral health: an evidence-based toolkit for prevention. London: Public Health England; 2014. www.phe.gov.uk. Accessed 31 Dec 2015.
Scottish Intercollegiate Guidelines Network. Dental interventions to prevent caries in children. Edinburgh: SIGN; 2014. (SIGN publication no. 138) [March 2014]. www.sign.ac.uk. Accessed 31 Dec 2015.
Sonis A, Ackerman M. E-space preservation. Angle Orthod. 2011;81:1045–9.
Rubin RL, Baccetti T, McNamara JA Jr. Mandibular second molar eruption difficulties related to the maintenance of arch perimeter in the mixed dentition. Am J Orthod Dentofac Orthop. 2012;141:146–52.
Mandall NA, McCord JF, Blinkhorn AS, Worthington HV, O’Brien KD. Perceived aesthetic impact of malocclusion and oral self-perceptions in 14-15-year-old Asian and Caucasian children in greater Manchester. Eur J Orthod. 2000;22:175–83.
Masood Y, Masood M, Zainul NN, Araby NB, Hussain SF, Newton T. Impact of malocclusion on oral health related quality of life in young people. Health Qual Life Outcomes. 2013;11:25.
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Kaklamanos, E.G., Lazaridou, D., Tsiantou, D. et al. Dental arch spatial changes after premature loss of first primary molars: a systematic review of controlled studies. Odontology 105, 364–374 (2017). https://doi.org/10.1007/s10266-016-0281-2
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DOI: https://doi.org/10.1007/s10266-016-0281-2