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Detection of a metastatic lesion and tiny yolk sac tumors in two teenage patients by FDG-PET: report of two cases

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Abstract

We herein report the efficacy of FDG-PET for detecting yolk sac tumors in two teenage patients. One patient had a rare bone metastasis and the other had tiny recurrent lesions at the mediastinum. Both lesions were difficult to detect by conventional diagnostic modalities. In contrast, FDG-PET was very effective for detecting these lesions. Furthermore, the SUVmax of the lesion reflected the tumor activity, which was also suggested by the fluctuating values of serum alpha-fetoprotein (AFP), an established marker of yolk sac tumors. FDG-PET may be a useful procedure to detect tiny and metastatic, pediatric yolk sac tumors.

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Conflict of interest

Masataka Takahashi and co-authors have no conflict of interest.

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Authors and Affiliations

  1. Department of Pediatric Surgery, The University of Tokyo Hospital, Tokyo, Japan

    Masataka Takahashi, Yutaka Kanamori & Tadashi Iwanaka

  2. Department of Radiology, The University of Tokyo Hospital, Tokyo, Japan

    Miwako Takahashi & Toshimitsu Momose

  3. Division of Surgery, Department of Surgical Specialities, National Center for Child Health and Development, 2-10-1 Okura Setagaya-ku, Tokyo, 157-8535, Japan

    Masataka Takahashi & Yutaka Kanamori

Authors
  1. Masataka Takahashi
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  2. Yutaka Kanamori
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  3. Miwako Takahashi
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  4. Toshimitsu Momose
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  5. Tadashi Iwanaka
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Correspondence to Yutaka Kanamori.

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Takahashi, M., Kanamori, Y., Takahashi, M. et al. Detection of a metastatic lesion and tiny yolk sac tumors in two teenage patients by FDG-PET: report of two cases. Surg Today 44, 1962–1965 (2014). https://doi.org/10.1007/s00595-013-0656-8

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  • DOI: https://doi.org/10.1007/s00595-013-0656-8

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