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Eosinophilic esophagitis investigated by upper gastrointestinal endoscopy in Japanese patients

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Abstract

Background

The prevalence of eosinophilic esophagitis (EE) is increasing rapidly in Western countries. Several case series of EE have also been reported in Japan. However, the prevalence of EE in Japanese patients as investigated by upper gastrointestinal endoscopy is unknown. Therefore, we carried out a prospective multicenter study to address this issue.

Methods

From July to December 2010, 23,346 patients who had undergone routine upper gastrointestinal endoscopy in 17 institutions were enrolled. In patients with symptoms suggesting EE, such as dysphasia, food impaction, and heartburn, and/or in patients in whom endoscopic findings suggested pathology, esophageal biopsy samples were collected, and the numbers of eosinophils in the squamous epithelium were counted.

Results

During the study period of 6 months, 4 patients were endoscopically and histologically diagnosed with EE. The prevalence of EE was calculated to be 17.1/100,000.

Conclusion

The prevalence of EE in Japanese patients by upper gastrointestinal endoscopy has now been documented.

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Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Division of Endoscopy, Shimane Prefectural Central Hospital, Izumo, Japan

    Hirofumi Fujishiro

  2. Division of Endoscopy, Shimane University Hospital, 89-1 Enya-cho, Izumo, Shimane, 693-8501, Japan

    Yuji Amano

  3. Division of Gastroenterology, Matsue Red Cross Hospital, Matsue, Japan

    Yoshinori Kushiyama

  4. Second Department of Internal Medicine, Shimane University, Faculty of Medicine, Izumo, Japan

    Shunji Ishihara & Yoshikazu Kinoshita

Authors
  1. Hirofumi Fujishiro
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  2. Yuji Amano
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  3. Yoshinori Kushiyama
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  4. Shunji Ishihara
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  5. Yoshikazu Kinoshita
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Corresponding author

Correspondence to Yuji Amano.

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Fujishiro, H., Amano, Y., Kushiyama, Y. et al. Eosinophilic esophagitis investigated by upper gastrointestinal endoscopy in Japanese patients. J Gastroenterol 46, 1142–1144 (2011). https://doi.org/10.1007/s00535-011-0435-5

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  • DOI: https://doi.org/10.1007/s00535-011-0435-5

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