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Endoscopic submucosal dissection for metachronous tumor in the remnant stomach after distal gastrectomy

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Abstract

Background

Endoscopic submucosal dissection (ESD) of tumor in the upper part of the stomach is technically difficult and has a high complication rate. We compared the feasibility and safety of ESD for metachronous tumor found in the remnant stomach after distal gastrectomy with ESD for tumor in the upper third of the intact stomach.

Patients and methods

We retrospectively compared clinical outcome and safety of 13 lesions (11 early gastric cancers (EGCs) and 2 dysplasias) in the remnant stomach and 30 lesions (28 EGCs and 2 dysplasias) in the upper third of the intact stomach. All patients were treated with ESD at a cancer center hospital.

Results

En bloc resection rates were 100% (13/13) for remnant gastric tumor and 87% (26/30) for upper-third tumor (p = 0.30). En bloc resection rates with tumor-free margins (R0 resection) were 92% (12/13) for remnant gastric tumor and 73% (22/30) for upper-third tumor (p = 0.24). Curative resection rates were 85% (11/13) for remnant gastric tumor and 67% (20/30) for upper-third tumor (p = 0.29). Median procedure duration for ESD was 68 min (range 32–233 min) in the remnant stomach and 78 min (range 45–261 min) in the intact stomach (p = 0.49). One case of perforation and one of delayed bleeding occurred in the upper-third tumor group, whereas none occurred in the remnant tumor group. Local recurrence was found in no patients in the remnant gastric tumor group but in one patient in the upper-third tumor group.

Conclusions

ESD for metachronous remnant gastric tumor was feasible and safe in comparison with ESD for tumor in the upper third of the intact stomach.

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Acknowledgment

This study was supported in part by grant 0910100 from the National Cancer Center, Korea.

Disclosures

Drs. JY Lee, SJ Cho, CG Kim, MC Kook, JH Lee, KW Ryu, YW Kim, and IJ Choi have no conflicts of interest or financial ties to disclose.

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Authors and Affiliations

  1. Research Institute and Hospital, National Cancer Center, Goyang, Korea

    Jong Yeul Lee, Il Ju Choi, Soo-Jeong Cho, Chan Gyoo Kim, Myeong-Cherl Kook, Jun Ho Lee, Keun Won Ryu & Young-Woo Kim

  2. Center for Gastric Cancer, National Cancer Center, 809 Madu 1-Dong, Ilsandong-gu, Goyang, Gyeonggi, 411-769, Korea

    Il Ju Choi

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  1. Jong Yeul Lee
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Correspondence to Il Ju Choi.

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Lee, J.Y., Choi, I.J., Cho, SJ. et al. Endoscopic submucosal dissection for metachronous tumor in the remnant stomach after distal gastrectomy. Surg Endosc 24, 1360–1366 (2010). https://doi.org/10.1007/s00464-009-0779-6

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  • DOI: https://doi.org/10.1007/s00464-009-0779-6

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