Abstract
Introduction
Nicolau syndrome (NS), also known as livedo-like dermatitis or embolia cutis medicamentosa, is a very rare complication of intramuscular and intraarticular injection of various drugs.
Case report
We herein report a case of NS developing approximately 2 h after the intramuscular administration of vitamin K1 in an extremely low birth weight premature newborn. To our knowledge, this patient is the youngest case suffering from such a livedoid skin necrosis and the first case of neonatal NS developing due to intramuscular administration of vitamin K1.
References
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We (the authors) did not have any financial relationship with any organization; furthermore, there have been no organization that sponsored the research.
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Koklu, E., Sarici, S.U., Altun, D. et al. Nicolau syndrome induced by intramuscular vitamin K in a premature newborn. Eur J Pediatr 168, 1541–1542 (2009). https://doi.org/10.1007/s00431-009-0964-6
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DOI: https://doi.org/10.1007/s00431-009-0964-6