Skip to main content

Advertisement

SpringerLink
Log in

Massive bilateral vitreoretinal hemorrhage in patient with chronic refractory idiopathic thrombocytopenic purpura

  • Case Report
  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

Abstract

Background

We describe a patient with chronic, refractory idiopathic thrombocytopenic purpura (ITP) who developed massive vitreoretinal hemorrhages in both eyes.

Methods

A 49-year-old woman complained of an acute decrease of vision, and ophthalmoscopy revealed bilateral preretinal and subretinal hemorrhages around the optic disc. Her platelet counts were less than 5000/μl in spite of repetitive administration of corticosteroids and immunoglobulins with splenectomy for the chronic refractory ITP. One month later, she developed massive vitreoretinal hemorrhages bilaterally, and vision decreased to hand-motion.

Results

Vitrectomy was performed on both eyes after medical treatment to increase platelet counts. The intraretinal hemorrhages were absorbed from the area around the disc and vision recovered to 20/100 in the right eye and 20/2000 in the left after one month.

Conclusion

Massive vitreoretinal hemorrhages can develop in patients with chronic refractory ITP, and vitrectomy can be beneficial for this condition.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Ben-Yehuda D, Gillis S, Eldeor A (1984) Clinical and therapeutic experience with idiopathic thrombocytopenic purpura. Israeli ITP study group. Acta Haematol 91:1–6

    Article  Google Scholar 

  2. Bussel J, Cines D (2000) Immune thrombocytopenic purpura, neonatal autoimmue thrombocytopenia, and post-transfusion purpura. In: Hoffman R, Benz EJ Jr, Shattil SJ, Furie B, Cohen HJ, Silberstein LE (eds) Hematology basic principles and practice, 3rd edn. Churchill Livingstone, New York, pp 2096–2114

    Google Scholar 

  3. Inoue T, Yanagi Y, Tamaki Y et al (2004) Massive subretinal hemorrhage secondary to age-related macular degeneration in a patient with idiopathic thrombocytopenic purpura. Eye 18:656–657

    Article  PubMed  CAS  Google Scholar 

  4. Rubenstein R, Yanoff M, Albert D (1968) Thrombocytopenia, anemia and retinal hemorrhage. Am J Ophthalmol 65:435–440

    PubMed  CAS  Google Scholar 

  5. Levine SP (2004) Thrombocytopenia caused by immunologic platelet destruction. In: Greer JP, Rodgers GM, Foerster J, Paraskevas F, Lukens JN, Glader B (eds) Wintrobe’s clinical hematology, 11th edn. Lippincott Williams & Wilkins, Philadelphia, pp 1533–1544

    Google Scholar 

  6. Sodhi PK, Jose R (2003) Subconjunctival Hemorrhage: the first presenting clinical feature of idiopathic thrombocytopenic purpura. Jpn J Ophthalmol 47:316–318

    Article  PubMed  Google Scholar 

  7. Williams GA (2001) Platelet disorders. In: Gold DH, Weingeist TA (eds) Color atlas of the eye in systemic disease. Lippincott Williams & Wilkins, Philadelphia, pp. 136–137

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Ophthalmology, Keio University of School of Medicine, 35 Shinanomachi, Shinjyuku-ku, Tokyo, 160-8582, Japan

    Amy Okuda, Makoto Inoue, Kei Shinoda & Kazuo Tsubota

Authors
  1. Amy Okuda
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Makoto Inoue
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kei Shinoda
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Kazuo Tsubota
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Makoto Inoue.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Okuda, A., Inoue, M., Shinoda, K. et al. Massive bilateral vitreoretinal hemorrhage in patient with chronic refractory idiopathic thrombocytopenic purpura. Graefe's Arch Clin Exp Ophthalmo 243, 1190–1193 (2005). https://doi.org/10.1007/s00417-005-1183-0

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00417-005-1183-0

Keywords

Search

Navigation