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Comparative outcomes of antireflux treatment for laryngopharyngeal reflux symptoms and upper abdominal symptoms in patients with endoscopic esophagitis

  • Laryngology
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Abstract

The objectives of this prospective study are to determine the prevalence of laryngopharyngeal reflux (LPR) symptoms in patients with endoscopic esophagitis, to investigate the relationship between LPR symptoms and upper abdominal symptoms of gastroesophageal reflux disease (GERD) and to compare the treatment responses of both symptom groups. 120 consecutive patients having complaints of GERD were included. Group I consisted of 62 patients with a diagnosis of endoscopic esophagitis. The second group consisted of 58 subjects with no detectable pathology at gastroscopy. LPR symptoms and upper abdominal symptoms were graded. Proton pump inhibitors (PPI) were prescribed to patients. Both groups of symptoms were compared in two groups of patients. The improvement in symptoms was evaluated after treatment. The frequencies of LPR symptoms were statistically higher in patients with endoscopic esophagitis. All LPR symptoms were statistically relieved in their frequency after treatment. The decrease in LPR symptom scores after treatment in group I was statistically significant. FSSG (frequency scale for the symptoms of GERD) scores were statistically higher in group I than in group II before treatment. After treatment, FSSG scores were significantly decreased in group I. There was statistically significant positive correlation between the LPR symptom scores and FSSG scores before treatment. In conclusion, there is a high incidence of LPR symptoms and upper abdominal symptoms in patients with endoscopic esophagitis. LPR and upper abdominal symptoms responded well to antireflux treatment in patients with endoscopic esophagitis.

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Authors and Affiliations

  1. Department of Gastroenterology, Istanbul Education and Research Hospital, 67600, Samatya, Istanbul, Turkey

    Ahmet Burak Toros

  2. Department of Otorhinolaryngology-Head and Neck Surgery, Haydarpasa Numune Education and Research Hospital, Istanbul, Turkey

    Sema Zer Toros

  3. Department of General Surgery, Haydarpasa Numune Education and Research Hospital, Istanbul, Turkey

    Leyla Ozel

  4. Department of General Surgery, Istanbul Education and Research Hospital, Istanbul, Turkey

    Feyzullah Ersoz

  5. Department of Internal Diseases, Istanbul Education and Research Hospital, Istanbul, Turkey

    Mustafa Saglam & Fettah Sametoglu

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  1. Ahmet Burak Toros
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  2. Sema Zer Toros
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  3. Leyla Ozel
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  4. Feyzullah Ersoz
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  5. Mustafa Saglam
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  6. Fettah Sametoglu
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Correspondence to Ahmet Burak Toros.

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Toros, A.B., Toros, S.Z., Ozel, L. et al. Comparative outcomes of antireflux treatment for laryngopharyngeal reflux symptoms and upper abdominal symptoms in patients with endoscopic esophagitis. Eur Arch Otorhinolaryngol 268, 703–708 (2011). https://doi.org/10.1007/s00405-010-1459-9

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  • DOI: https://doi.org/10.1007/s00405-010-1459-9

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