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Sinonasal fibro-osseous hamartoma: case presentation and differential diagnosis with other fibro-osseous lesions involving the paranasal sinuses

  • Rhinology
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Abstract

We present the case of a 2-year-old girl who was referred to the ENT Department of the Antwerp University with a bony obstruction of the left side of the nose. The lesion originated from the ethmoid roof and the middle turbinate and extended into the nasopharynx. A partial functional resection was performed using an endoscopic approach. A combination of clinical, radiographic and histological information permitted a diagnosis of a benign fibro-osseous lesion: sinonasal hamartoma. The benign nature of this tumor justified a conservative follow-up.

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References

  1. Albrecht E (1904) Uber Hamartoma. Verhandlungen der Deutchen pathologischen Gesellschaft 7:153–157

    Google Scholar 

  2. Willis RA (1968) Some unusual developmental heterotopias. Br Med J 3:267–272

    PubMed  Google Scholar 

  3. Kacker SK, Dasgupta G (1973) Hamartomas of the ear and nose. J Laryngol Otol 87:801–805

    PubMed  Google Scholar 

  4. Mc Dermott MB, Ponder TB, Dehner LP (1998) Nasal chondromesenchymal hamartoma. Am J Surg Pathol 22:425–433

    Article  PubMed  Google Scholar 

  5. Shet T, Borges A, Nair C, Desai S, Mistry R (2004) Two unusual lesions in the nasal cavity of infants—a nasal chondromesenchymal hamartoma and an aneurismal bone cyst-like lesion. More closely related than we think? Int J Pediatr Otorhinolaryngol 68:359–364

    Article  PubMed  Google Scholar 

  6. Flavin R, Russel J, Phelan E, Mc Dermott MB (2005) Chondro-osseous respiratory epithelial adenomatoid hamartoma of the nasal cavity: a case report. Int J Pediatr Otorhinolaryngol 69:87–91

    Article  PubMed  Google Scholar 

  7. Adair CF, Thompson LDR, Wenig BM, Heffner DK (1996) Chondro-osseous and respiratory epithelial hamartomas of the sinonasal tract and nasopharynx. Mod Pathol 9:100

    Google Scholar 

  8. Harrison DFN (1984) Osseous and fibro-osseous conditions affecting the craniofacial bones. Ann Otol Rhinol Laryngol 93:199–203

    PubMed  Google Scholar 

  9. Brannon RB, Fowler CB (2001) Benign fibro-osseous lesions: a review of current concepts. Adv Anatom Pathol 8:126–143

    Article  Google Scholar 

  10. Alawi F (2002) Benign fibro-osseous diseases of the maxillofacial bones. Am J Clin Pathol 118 [Suppl 1]:S50–S70

    Google Scholar 

  11. Waldron CA (1993) Fibro-osseous lesions of the jaws. J Oral Maxillofac Surg 51:828–835

    PubMed  Google Scholar 

  12. Koury ME, Regezi RA, Perrot DH, Kaban LB (1995) Atypical fibro-osseous lesions: diagnostic challenges and treatment concepts. Int J Oral Maxillofac Surg 24:162–169

    PubMed  Google Scholar 

  13. Tumours of undefined neoplastic nature (2002) In: Fletcher CDM, Uni KK, Mertens F (eds) World Health Organization classification of tumours. Pathology and genetics of tumours of soft tissue and bone. IARC Press, Lyon, pp 337–348

  14. Pilch BZ (2001) Fibro-osseous lesions. In: Pilch BZ (ed) Head and neck surgical pathology. Lippincott Williams & Wilkins, Philadelphia, pp 453–454

  15. Brodish BN, Morgan CE, Sillers MJ (1999) Endoscopic resection of fibro-osseous lesions of the paranasal sinuses. Am J Rhinol 13:111–116

    PubMed  Google Scholar 

  16. Mirra JM, Gold RH, Picci P (eds) (1989) Osseous tumors of intramedullary origin. Lea and Febiger, Philadelphia, pp 174–179

  17. Rosai J (2004) Mandible and maxilla. In: Rosai J (ed) Surgical pathology. Mosby, London, pp 279–304

  18. Van Rompaey D, Schmelzer B, Verstraete W, Cammaert T (1994) Fibrous dysplasia in the frontoethmoidal complex: diagnosis and surgical aspects. Acta Otorhinolaryngol Belg 48:37–40

    PubMed  Google Scholar 

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Acknowledgements

We would like to thank Professor P.C.W. Hogendoornfrom the Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands, and the President of the Netherlands Committee on Bone Tumors for his second opinion of the histological features of this lesion and critical review of the manuscript. We also thank Dr. J. Claes, surgeon at the ENT department of the Antwerp University Hospital, for his comments on the manuscript and preparation of the photographs.

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Correspondence to A. N. Boudewyns.

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Boudewyns, A.N., van Dinther, J.J.S. & Colpaert, C.G. Sinonasal fibro-osseous hamartoma: case presentation and differential diagnosis with other fibro-osseous lesions involving the paranasal sinuses. Eur Arch Otorhinolaryngol 263, 276–281 (2006). https://doi.org/10.1007/s00405-005-1001-7

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