Skip to main content

Advertisement

Log in

Complete hydatidiform mole with coexistent live fetus in dichorionic twin gestation

  • Case Report
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Case report

A 28-year-old patient gravida 3, para 2 was admitted at 16 weeks’ gestation with the diagnosis of complete hydatidiform mole with coexistent live fetus (CHMCF) in dichorionic twin gestation. The βHCG level was 530,000 mIU/ml. The pregnancy was terminated by hysterotomy.

Outcome

Histopathologic analysis revealed a hydatidiform mole and a 17-week-old male fetus attached to the normal looking placenta by a double-vesseled cord. A final karyotype on cord blood samples confirmed normal 46 XY. Weekly performed serial βHCG values showed declining trend and were undetectable by 10 weeks post delivery.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  1. Vassilakos P, Riotton G, Kajii T (1977) Hydatidiform mole: two entities. A morphologic and cytogenetic study with some clinical considerations. Am J Obstet Gynaecol 127:167–170

    CAS  Google Scholar 

  2. Szulman AE, Surti U (1978) The syndromes of hydatidiform mole. Cytogenic and morphologic correlations. Am J Obstet Gynaecol 131:665–671

    CAS  Google Scholar 

  3. Beischer NA (1961) Hydatidiform mole with coexistent foetus. J Obstet Gynaecol Br Cwlth 68:231–237

    CAS  Google Scholar 

  4. Jones WB, Lauersen NH (1975) Hydatidiform mole with co-existent fetus. Am J Obstet Gynecol 122:267–272

    CAS  PubMed  Google Scholar 

  5. Jauniaux E, Brown R, Snijders RJM, Noble P, Nicolaides KH (1997) Early prenatal diagnosis of triploidy. Am J Obstet Gynecol 176:550–554

    CAS  PubMed  Google Scholar 

  6. Stellar MA, Genest DR, Bernstein MR, Lage JM, Goldstein DP, Berkowitz RS (1994) Clinical features of multiple conception with partial or complete molar pregnancy and coexisting fetuses. J Reprod Med 39:147–154

    PubMed  Google Scholar 

  7. Stellar MA, Genest DR, Bernstein MR, Large JM, Goldstein DR, Berkowitz RS (1994) Natural history of twin pregnancy with complete hydatidiform mole and coexisting fetus. Obstet Gynecol 83:35–42

    PubMed  Google Scholar 

  8. Wax JR, Pinette MG, Chard R, Blackstone J, Cartin A (2003) Prenatal diagnosis by DNA polymorphism analysis of complete mole with coexisting twin. Am J Obstet Gynecol 188:1105–1106

    Article  PubMed  Google Scholar 

  9. Block MF, Merrill JA (1982) Hydatidiform mole with coexistent fetus. Obstet Gynecol 60:129–134

    CAS  PubMed  Google Scholar 

  10. Thomas EJ, Pryce WI, Maltby EL (1987) The prospective management of a coexistent hydatidiform mole and fetus. Aust NZ J Obstet Gynaecol 27:343–345

    CAS  Google Scholar 

  11. Lage JM, Mark SD, Roberts DJ, Goldstein DP, Bernstein MR, Berkowitz RS (1992) A flow cytometric study of 137 fresh hydropic placentas: correlation between types of hydatidiform moles and nuclear DNA ploidy. Obstet Gynecol 79:403–410

    CAS  PubMed  Google Scholar 

  12. Fishman DA, Padilla LA, Keh P, Cohen L, Fredericksen M, Lurain JR (1998) Management of twin pregnancies consisting of a complete hydatidiform mole and normal fetus. Obstet Gynecol 51:546–550

    Article  Google Scholar 

  13. Abbi M, Kriplani A, Uppal R, Takkar D (1999) Term twin pregnancy with hydatidiform mole and a normal fetus. Arch Gynecol Obstet 262:189–191

    Article  CAS  PubMed  Google Scholar 

  14. Bruchim I, Kidron D, Amiel A, Altaras M, Fejgin MD (2000) Complete hydatidiform mole and a coexistent viable fetus: report of two cases and review of the literature. Gynecol Oncol 77:197–202

    CAS  PubMed  Google Scholar 

  15. Matsui H, Sekiya S, Hando T, Wake N, Tomodo Y (2000) Hydatidiform mole coexistent with twin live fetus: a national collaborative study in Japan. Hum Reprod 15:608–611

    Article  CAS  PubMed  Google Scholar 

  16. Bristow RE, Shumway JB, Khouzami AN, Witter FR (1996) Complete hydatidiform mole and surviving co-existent twin. Obstet Gynaecol Survey 51:705–709

    Article  CAS  Google Scholar 

  17. Sebire NJ, Foskett M, Paradinas FJ, Fisher RA, Francis RJ, Short D, Newlands ES, Seckl MJ (2002) Outcome of twin pregnancies with complete hydatidiform mole and healthy co-twin. Lancet 359:2165–2166

    Article  PubMed  Google Scholar 

  18. Montes-de-Oca-Valero F, Macara L, Shaker A (1999) Twin pregnancy with a complete hydatidiform mole and co-existing fetus following in-vitro fertilization: case report. Hum Reprod 14:2905–2907

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Serap Yaltı.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Özarpacı, C., Yaltı, S., Gürbüz, B. et al. Complete hydatidiform mole with coexistent live fetus in dichorionic twin gestation. Arch Gynecol Obstet 271, 271–274 (2005). https://doi.org/10.1007/s00404-004-0642-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00404-004-0642-x

Keywords

Navigation