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Coexisting Behçet’s disease and ankylosing spondylitis presented with deep venous thrombosis: a case report and review of the literature

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Abstract

The coexistence of Behçet’s disease (BD) and ankylosing spondylitis (AS) is a rare combination and described only in case reports in the literature. Although the number of reports is increasing, vascular thrombosis, which is characteristic feature of BD, was not reported in this combination until now. We present a case of a male patient with both BD and AS, presenting with deep venous thrombosis. We also reviewed the clinical features of the cases with coexistence of BD and AS.

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References

  1. Olivieri I, Gemignani G, Busoni F, Pecori F, Camerini E, Trippi D, Pasero G (1988) Ankylosing spondylitis with predominant involvement of the cervical spine in a woman with Behçet’s syndrome. Ann Rheum Dis 47(9):780–783

    Article  PubMed  CAS  Google Scholar 

  2. Kallel MH, Bejia I, Fournié B, Fournié A (1995) Behçet syndrome with ankylosing spondylitis. Rev Rhum Engl Ed 62(4):295–299

    PubMed  CAS  Google Scholar 

  3. Tosun M, Uslu T, Ibrahim Imamoglu H, Bahadir S, Erdolu S, Guler M (1996) Coexisting ankylosing spondylitis and Behçet’s disease. Clin Rheumatol 15(6):619–620

    Article  PubMed  CAS  Google Scholar 

  4. Beiran I, Scharf J, Dori D, Miller B (1995) A change in ocular involvement in a patient suffering from ankylosing spondylitis and Behçet’s disease. Eur J Ophthalmol 5(3):192–194

    PubMed  CAS  Google Scholar 

  5. Borman P, Bodur H, Ak G, Bostan EE, Barça N (2000) The coexistence of Behçet’s disease and ankylosing spondylitis. Rheumatol Int 19(5):195–198

    Article  PubMed  CAS  Google Scholar 

  6. Chang HK, Cho EH, Kim JU, Herr H (2000) A case of coexisting Behçet’s disease and ankylosing spondylitis. Korean J Intern Med 15(1):93–95

    PubMed  CAS  Google Scholar 

  7. Etaouil N, Benyahya E, Bennis R, Mkinsi O (2002) Ankylosing spondylitis and Behçet’s disease in combination. Two case reports. Joint Bone Spine 69(1):96–98

    Article  PubMed  Google Scholar 

  8. Cimen OB, Sahin G, Biçer A, Erdoğan C (2002) Behçet’s syndrome coexisting with clinically occult ankylosing spondylitis. Z Rheumatol 61(4):440–442

    Article  PubMed  Google Scholar 

  9. Kotevoglu N (2003) Coexistence of ankylosing spondylitis and Behcet’s disease. Two cases with atypical presentation and course. Scand J Rheumatol 32(3):184–185

    Article  PubMed  CAS  Google Scholar 

  10. Yildiz N, Alkan H, Ardic F, Topuz O (2009) Successful treatment with adalimumab in a patient with coexisting Behçet’s disease and ankylosing spondylitis. Rheumatol Int 25. [Epub ahead of print]

  11. Koç Y, Güllü I, Akpek G, Akpolat T, Kansu E, Kiraz S, Batman F, Kansu T, Balkanci F, Akkaya S et al (1992) Vascular involvement in Behçet’s disease. J Rheumatol 19(3):402–410

    PubMed  Google Scholar 

  12. El Ramahi KM, Al Dalaan A, Al Shaikh A, Al Meshari K, Akhtar M (1998) Renal involvement in Behçet’s disease: review of 9 cases. J Rheumatol 25(11):2254–2260

    PubMed  CAS  Google Scholar 

  13. Yoo WH, Kim HK, Park JH, Park TS, Baek HS (2000) Mediastinal mass and brachial plexopathy caused by subclavian arterial aneurysm in Behçet’s disease. Rheumatol Int 19(6):227–230

    Article  PubMed  CAS  Google Scholar 

  14. Blanchard B, Lazareth I, Brossel C, Saporta L, Letanoux M, Priollet P (1991) Lupus anticoagulant and leg ulcers associated with ankylosing spondylitis. J Rheumatol 18(12):1922–1923

    PubMed  CAS  Google Scholar 

  15. Mateo L, Juanola X, Nolla JM, del Blanco J, Rubio F, Roig Escofet D (1992) Antiphospholipid syndrome in patients with ankylosing spondylitis. Presentation of 2 cases. Med Clin (Barc) 98(10):381–383

    CAS  Google Scholar 

  16. Van der Linden S, Valkenburg HA, Cats A (1984) Evaluation of diagnostic criteria for ankylosing spondylitis: a proposal for modification of the New York criteria. Arthritis 27:361–368

    Article  Google Scholar 

  17. The International Study Group for Behçet’s disease (1992) Evaluation of diagnostic (‘classification’) criteria in Behçet’s disease-towards internationally agreed criteria. Br J Rheumatol 31(5):299–308

    Article  Google Scholar 

  18. Hochberg MC, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH (2008) Rheumatology, 4th edn. Mosby/Elsevier, Philadelphia, pp 1109–1114, 1561–1565

  19. Hazleman BL (1996) Rheumatic disorders of the eye and the various structures involved. Br J Rheumatol 35(3):258–268

    Article  PubMed  CAS  Google Scholar 

  20. Kansu E, Ozer FL, Akalin E, Güler Y, Zileli T, Tanman E, Kaplaman E, Müftüoğlu E (1972) Behçet’s syndrome with obstruction of the venae cavae. A report of seven cases. Q J Med 41(162):151–168

    PubMed  CAS  Google Scholar 

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Correspondence to Wan-Hee Yoo.

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Yoo, WH. Coexisting Behçet’s disease and ankylosing spondylitis presented with deep venous thrombosis: a case report and review of the literature. Rheumatol Int 32, 1793–1796 (2012). https://doi.org/10.1007/s00296-010-1439-9

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  • DOI: https://doi.org/10.1007/s00296-010-1439-9

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