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Angioinvasion durch neuroendokrinen Jejunumtumor

Darstellung eines Malignitätszeichens durch Acetonkompression

Angioinvasion by neuroendocrine jejunal tumor

Demonstration of a malignancy sign by acetone compression

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Zusammenfassung

Neuroendokrine Neoplasien des Verdauungstrakts werden nach aktueller WHO-Klassifikation gemäß Proliferation und Differenzierung in neuroendokrine Tumoren (NET) G1 und G2 sowie neuroendokrine Karzinome (NEC) eingeteilt. NET G1 proliferieren gering und zeigen meist einen günstigen klinischen Verlauf ohne Ausbildung von Metastasen. Im vorliegenden Fall zeigte sich eine Angioinvasion durch einen pT3 NET G1 nach Aufarbeitung des mesenterialen Fettgewebes mittels Acetonkompression. Dieser Befund und die lokale Ausdehnung deuten auf einen ungünstigen Krankheitsverlauf hin, der aufmerksamer Nachsorge bedarf.

Abstract

Neuroendocrine neoplasms of the digestive system are classified by current World Health Organization (WHO) guidelines as G1 and G2 neuroendocrine tumors (NET) as well as neuroendocrine carcinoma (NEC) based on proliferation and differentiation. The G1 NET tumors are highly differentiated, low proliferating and usually exhibit a favorable course of the disease without the development of metastases. In the case presented here, angioinvasion by a pT3 NET G1 was demonstrated after complete work-up of the mesenterial fat by acetone compression. The findings indicate an unfavorable course of disease requiring intensive surveillance.

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Authors and Affiliations

  1. Institut für Pathologie Nordhessen, Germaniastr. 7, 34119, Kassel, Deutschland

    A.H. Scheel & J. Rüschoff

  2. Universitätsmedizin Göttingen, Göttingen, Deutschland

    J. Kitz & P. Ströbel

  3. Marienkrankenhaus Kassel, Kassel, Deutschland

    J. Heimbucher

Authors
  1. A.H. Scheel
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  2. J. Kitz
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  3. J. Heimbucher
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  4. P. Ströbel
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  5. J. Rüschoff
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Corresponding author

Correspondence to A.H. Scheel.

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Scheel, A., Kitz, J., Heimbucher, J. et al. Angioinvasion durch neuroendokrinen Jejunumtumor. Pathologe 34, 352–355 (2013). https://doi.org/10.1007/s00292-012-1737-y

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  • DOI: https://doi.org/10.1007/s00292-012-1737-y

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