Summary
A child with ulcerative colitis is described in whom many unusual complications of the disease occurred. Arthritis was present and preceded the onset of the colitis. The patient also developed vasculitis, hepatitis, pleuritis, pericarditis, cryoglobulinemia, and disseminated intra-vascular coagulopathy. A review of the literature on ulcerative colitis revealed the relative infrequent occurrence of many of these manifestations in the pediatric age group.
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References
Kirsner, J.B. The local and systemic complications of inflammatory bowel disease. Arthritis Rheum, 1980, 23, 1359–1365.
Daum, F., Aiges, H.W. Inflammatory bowel disease in children. In: Disorders in Pediatric Gastroenterology and Nutrition, Editor: Lifshitz F., New York, Marcel Dekker, 1980, 147–157.
Daum, F., Aiges, H.W. Inflammatory bowel disease. In: Pediatric Gastroenterology, Editor: Silverberg M., New York, Medical Examination Pulishing Co., 1983, 340–357.
Davidson, M., Silverberg, M. Ulcerative colitis. In: Pediatrics, Editor: Rudolph A.M., East Norwalk, CT. Appleton-Century-Crofts, 1982, 981–984.
Spiro, H. In: Clinical Gastroenterology, New York, Macmillan, 1983, 925–965.
Johnson, M.L., Wilson, H.T.H. Skin lesions in ulcerative colitis. Gut, 1969, 10, 255–263.
Wackers, F.J., Tutgat, G.N., Vreeken, J. Necrotizing vasculitis and ulcerative colitis. Br Med J, 1974, 4, 83–84.
Haslock, I., Wright, V. The arthritis associated with intestinal disease. Bull Rheum Dis, 1974, 24, 750–755.
Enlow, R.W., Bias, W.B., Arnett, F.C. The spondylitis of inflammatory bowel disease. Arthritis Rheum, 1980, 23, 1359–1365.
Greenstein, A.J., Janowitz, H.D., Sachar, D.B. The extra-intestinal complications of Crohn's disease and ulcerative colitis: A study of 700 patients. Medicine, 1976, 55, 401–412.
Patwardhan, R.V., Heilpern, R.J., Brewster, A.C. Pleuropericarditis: An extra-intestinal complication of inflammatory bowel disease. Arch Intern Med, 1983, 143, 94–96.
Collins, W.J., Bendig, D.W., Taylor, W.F. Pulmonary vasculitis complicating childhood ulcerative colitis. Gastroenterol, 1979, 77, 1081–1093.
Barabado, F.J., Vazquez, J.J., Gil, A., Vazquez, J.D. Vasculitis and ulcerative colitis. Gastroenterol, 1980, 79, 417–418.
Isenberg, J.I., Goldstein, H., Korn, A.R., Ozeran, R.S., Rosen, V.R. Pulmonary vasculitis — an uncommon complication of ulcerative colitis. N Engl J Med, 1968, 279, 1376–1377.
Polcak, J., Wiedermann, D., Polcakova, J. Immunochemical and immunoelectrophoretic characteristics of cryoprotein and formol-gel test in the sera of patients with ulcerative colitis. Gastroenterol, 1967, 107, 272–282.
Ball, G.V., Goldman, L.N. Chronic ulcerative colitis, skin necrosis, and cryofibrinogenemia. Ann Intern Med, 1976, 85, 464–466.
Kehoe, E.L., Newcomer, C.K.L. Thromboembolic phenomena in ulcerative colitis. Arch Intern Med, 1964, 113, 712–714.
Bargen, J.A., Barker, N.W. Extensive arterial and venous thrombosis complicating chronic ulcerative colitis. Arch Intern Med, 1936, 58, 17–31.
Lam, A., Borda, I.T., Inwood, M.J., Thomson, S. Coagulation studies in ulcerative colitis and Crohn's disease. Gastroenterol, 1975, 68, 245–251.
Hibi, T., Aiso, S., Yoshida, T., Watanabe, M., Asakura, H., Tsuru, S., Tsuchiya, M. Anti-colon antibody and lymphocytophilic antibody in ulcerative colitis. Clin. Exp. Immunol. 1982, 49, 75–80.
Kemler, B.J., Alpert, E. Inflammatory bowel disease associated circulating immune complexes. Gut, 1980, 21, 195–201.
Hodgson, H.J.F., Potter, B.J., Hewell, D.P. Immune complexes in ulcerative colitis and Crohn's disease. Clin Exp Immunol, 1977, 29, 187–196.
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Speiser, J.C., Moore, T.L. & Zuckner, J. Ulcerative colitis with arthritis and vasculitis. Clin Rheumatol 4, 343–347 (1985). https://doi.org/10.1007/BF02031620
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DOI: https://doi.org/10.1007/BF02031620