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Diagnosis of acute myocardial infarction in the emergency room

A prospective assessment of clinical decision making and the usefulness of immediate cardiac enzyme determination

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Abstract

This study evaluates (a) the ability of house staff physicians to diagnose acute myocardial infarction (AMI) in patients with chest pain and (b) the usefulness of immediate (“stat”) creatine kinase determinations in aiding the decision to hospitalize patients with chest pain. Of 80 emergency room patients with chest pain, 34 were admitted to an intensive care unit and 46 were either discharged or admitted to a general medical unit. Of the 34 patients admitted to intensive care, 11 fulfilled criteria for AMI. Of the 46 who were not admitted, two met criteria for AMI: one had abnormal initial enzyme values; the other had normal initial values but diagnostic 48-hour values. Both had abnormal electrocardiograms. On the other hand, 11 patients who were not admitted had elevated initial enzyme values but did not have myocardial infarctions and might have been admitted inappropriately on the basis of their initial enzyme values. Five patients who were admitted had normal initial values but did develop infarctions and might have been sent home inappropriately on the basis of initial enzyme values. We conclude that: (a) physicians discharged 2 of 13 patients with AMI drawn from a population of 80 with chest pain and (b) the availability of stat cardiac enzymes could have prevented the discharge of only 1 patient and may have caused the inappropriate admission of 11 and discharge of 5 patients.

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References

  1. Martin SP, Donaldson MC, London CD, et al: Inputs into coronary care during 30 years: A cost effectiveness study.Ann Intern Med 81289–301, 1974.

    Google Scholar 

  2. Bloom BS, Peterson OL: End results, cost and productivity of coronary-care units.N Engl J Med 28872–78, 1973.

    Google Scholar 

  3. Hill JD, Hampton JR, Mitchell JRA: A randomized trial of home-versus-hospital management for patients with suspected myocardial infarction.Lancet 1837–841, 1978.

    Google Scholar 

  4. Hofvendahl S: Influence of treatment in a coronary care unit on prognosis in acute myocardial infarction.Acta Med Scand [Suppl 5191–78, 1971.

    Google Scholar 

  5. Swan HJC, Blackburn HW, DeSanctis R, et al: Duration of hospitalization in “uncomplicated complete acute myocardial infarction.”Am J Cardiol 37413–419, 1976.

    Google Scholar 

  6. Kleiger RE: Chest pain in patients seen in emergency clinics.JAMA 236595–597, 1976.

    Google Scholar 

  7. Beard OW, Hipp HR, Robins M, et al: Initial myocardial infarction among 503 veterans: Five year survival.Am J Med 28871–883, 1960.

    Google Scholar 

  8. Galen RD, Reiffel JA, Gambino SK: Diagnosis of acute myocardial infarction.JAMA 232145–147, 1975.

    Google Scholar 

  9. Varat MA, Mercer DW: Cardiac specific creatine phosphokinase isoenzymes in the diagnosis of acute myocardial infarction.Circulation 51855–859, 1975.

    Google Scholar 

  10. Guzy PM: Creatine phosphokinase—MB and the diagnosis of myocardial infarction.West J Med 127455–460, 1977.

    Google Scholar 

  11. Roseman MD: Painless myocardial infarction: A review of the literature and analysis of 220 cases.Ann Intern Med 411–8, 1954.

    Google Scholar 

  12. Margolis JR, Kannel WB, Feinleib M, et al: Clinical features of unrecognized myocardial infarction—silent and symptomatic.Am J Cardiol 321–7, 1973.

    Google Scholar 

  13. Medalie JH, Goldbourt U: Unrecognized myocardial infarction: Five-year incidence, mortality and risk factors.Ann Intern Med 84526–531, 1976.

    Google Scholar 

  14. Schor S, Behar S, Mordan B, et al: Disposition of presumed coronary patients from an emergency room.JAMA 236941–943, 1976.

    Google Scholar 

  15. Nevine MA, Saran M, Bright M, et al: Pitfalls in interpreting serum creatine phosphokinase activity.JAMA 2241382–1387, 1973.

    Google Scholar 

  16. Eisenberg JM, Rose JD, Weinstein AJ: Routine blood cultures from febrile outpatients: Use in detecting bacteremia.JAMA 2362863–2865, 1976.

    Google Scholar 

  17. McGowan JE, Bratton L, Klein JO, et al: Bacteremia in febrile children seen in a “walk-in pediatric clinic”.N Engl J Med 2881309–1312, 1975.

    Google Scholar 

  18. Sisson JC, Schoomaker EB, Ross JC: Clinical decision analysis: The hazard of using additional data.JAMA 2361259–1263, 1976.

    Google Scholar 

  19. Posen MW, D'Agostino RB, Mitchell JB, et al: The utility of a predictive model for ischemic heart disease in changing hospital admitting practices.Clin Res 26336 A, 1978.

    Google Scholar 

  20. Leaper DJ, Horrochs JC, Staniland JR, et al: Computer-assisted diagnosis of abdominal pain using estimates provided by clinicians.Br Med J 2350–354, 1972.

    Google Scholar 

  21. Bennett B, Teasdale G: Predicting outcome in individual patients after severe head injury.Lancet 11031–1034, 1976.

    Google Scholar 

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Additional information

At the time this study was conducted, the authors were with the Departments of Medicine and Pathology, University of Pennsylvania, Philadelphia, Pennsylvania. Reprint requests should be addressed to Dr. Eisenberg, Silverstein 3, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, Pennsylvania 19104. Dr. Arvan's current address is Strong Memorial Hospital, Rochester, New York. Dr. Rawnsley's current address is Mary Hitchcock Memorial Hospital, Hanover, New Hampshire. This work was supported in part by the Clinical Scholars Program, Robert Wood Johnson Foundation, Princeton, N. J., by Training Grant A07AH00331 from the Public Health Service, and by the National Health Care Management Center at the Leonard Davis Institute of Health Economics, University of Pennsylvania. The opinions, conclusions, and proposals in this text are those of the authors and do not necessarily represent those of the Robert Wood Johnson Foundation or the National Health Care Management Center. The authors acknowledge the valuable advice and cooperation of Drs. Samuel Martin, Joel Morganroth, and William Hanson, the staffs of the Hospital of the University of Pennsylvania emergency room and clinical laboratory, and the house staff who participated in this study.

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Eisenberg, J.M., Horowitz, L.N., Busch, R. et al. Diagnosis of acute myocardial infarction in the emergency room. J Community Health 4, 190–198 (1979). https://doi.org/10.1007/BF01322964

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  • DOI: https://doi.org/10.1007/BF01322964

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