Skip to main content
SpringerLink
Log in

Biology and biochemistry of papillomaviruses

  • Chapter
  • First Online:
Reviews of Physiology, Biochemistry and Pharmacology, Volume 99

Part of the book series: Reviews of Physiology, Biochemistry and Pharmacology ((REVIEWS,volume 99))

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Abbreviations

A:

Adenine

bp:

base pairs=pairs of nucleotides

BPV:

bovine papillomavirus

C:

cytosine

COPV:

canine oral papillomavirus

CRPV:

cottontail rabbit (Shope) papillomavirus

DNA:

deoxyribonucleic acid

Ev:

epidermodysplasia verruciformis

G:

guanine

HPV:

human papillomavirus

MnPV:

Mastomys natalensis papillomavirus (virus of the multi-mammate mouse)

mRNA:

messenger ribonucleic acid

RNA:

ribonucleic acid

SV40:

simian virus 40

T:

thymine

References

  • Aaronson DM, Lutzner MA (1967) Epidermodysplasia verruciformis and epidermoid carcinoma. J Am Med Wom Assoc 201:775–777

    Article  Google Scholar 

  • Almeida JD, Goffe AP (1965) Antibody to wart virus in human sera demonstrated by electron microscopy and precipitin tests. Lancet II:1205–1207

    Article  Google Scholar 

  • Almeida JD, Howatson AF, Williams MG (1962) Electron microscope study of human warts: Sites of virus production and nature of the inclusion bodies. J Invest Dermatol 38:337–345

    PubMed  Google Scholar 

  • Amtmann E, Sauer G (1982a) Activation of non-expressed bovine papilloma virus genomes by tumour promoters. Nature 296:675–677

    Article  PubMed  Google Scholar 

  • Amtmann E, Sauer G (1982b) Bovine papilloma virus transcription: Polyadenylated RNA species and assessment of the direction of transcription. J Virol 43:59–66

    PubMed  Google Scholar 

  • Amtmann E, Müller H, Sauer G (1980) Equine connective tissue tumors contain unintegrated bovine papilloma virus DNA. J Virol 35:962–964

    PubMed  Google Scholar 

  • Archard HO, Heck JW, Stanley HR (1965) Focal epithelial hyperplasia: An unusual oral mucosal lesion found in Indian children. Oral Surg 20:201–212

    Article  PubMed  Google Scholar 

  • Barrera-Oro JG, Smith KO, Melnick JL (1962) Quantitation of papovavirus particles in human warts. J Natl Cancer Inst 29:583–595

    PubMed  Google Scholar 

  • Barthold SW, Olson C (1978) Common membrane neoantigen on bovine papilloma virus-induced fibroma cells from cattle and horses. Am J Vet Res 39:1643–1645

    PubMed  Google Scholar 

  • Benoist C, Chambon P (1981) In vivo sequence requirements of the SV40 early promoter region. Nature 290:304–310

    Article  PubMed  Google Scholar 

  • Berman A, Winkelmann RK (1977) Flat warts undergoing involution: Histopathological findings. Arch Dermatol 113:1219–1221

    Article  PubMed  Google Scholar 

  • Berman A, Winkelmann RK (1980) Involuting common warts. J Am Acad Dermatol 3:356–362

    PubMed  Google Scholar 

  • Berman A, Domnitz JM, Winkelmann RK (1982) Plantar warts recently turned black. Arch Dermatol 118:47–51

    Article  PubMed  Google Scholar 

  • Binetruy B, Meneguzzi G, Breathnach R, Cuzin F (1982) Recombinant DNA molecules comprising bovine papilloma virus type 1 DNA linked to plasmid DNA are maintained in a plasmidial state both in rodent fibroblasts and in bacterial cells. EMBO J 1:621–628

    PubMed  Google Scholar 

  • Black PH, Hartley JW, Rowe WP, Huebner RJ (1963) Transformation of bovine tissue culture cells by bovine papilloma virus. Nature (Lond) 199:1016–1018

    PubMed  Google Scholar 

  • Blanchet-Bardon C, Puissant A, Lutzner M, Orth G, Nutini MT, Guesry P (1981) Interferon treatment of skin cancer in patients with epidermodysplasia verruciformis. Lancet I:274

    Article  Google Scholar 

  • Boiron M, Levy JP, Thomas M, Friedman JC, Bernard J (1964) Some properties of bovine papilloma virus. Nature (Lond) 201:423–424

    PubMed  Google Scholar 

  • Boiron M, Thomas M, Chenialle PH (1965) A biological property of deoxyribonucleic acid extracted from bovine papilloma virus. Virology 52:150–153

    Article  Google Scholar 

  • Boon ME, Fox CH (1981) Simultaneous condyloma acuminata and dysplasia of the uterine cervix. Acta Cytol 25:393–399

    PubMed  Google Scholar 

  • Bosse K, Christophers E (1964) Beitrag zur Epidemiologie der Warzen. Hautarzt 15:80–86

    PubMed  Google Scholar 

  • Boyle WF, Riggs JL, Oshiro JS, Lennette EH (1973) Electron microscopic identification of papovavirus in laryngeal papilloma. Laryngoscope 83:1102–1108

    PubMed  Google Scholar 

  • Breedis C, Berwick L, Anderson TF (1962) Fractionation of Shope papilloma virus in cesium chloride density gradients. Virology 17:84–94

    Article  PubMed  Google Scholar 

  • Breitburd F, Favre M, Zoorob R, Fortin D, Orth G (1981) Detection and characterization of viral genomes and search for tumoral antigens in two hamster cell lines derived from tumors induced by bovine papillomavirus type 1. Int J Cancer 27:693–702

    PubMed  Google Scholar 

  • Brodersen I, Genner J (1973) Histological and immunological observations on common warts in regression. Acta Derm Venereol (Stockh) 53:461–464

    PubMed  Google Scholar 

  • Bryan WR, Beard JW (1940) Correlation of frequency of positive inoculations with inoculation period and concentration of purified papilloma protein. J Infect Dis 66:245–253

    Google Scholar 

  • Bunney MH (1982) Viral warts: Their biology and treatment. Oxford University Press, Oxford

    Google Scholar 

  • Buschke A, Löwenstein L (1931) Über carcinomähnliche Condylomata acuminata des Penis. Arch Dermatol Syph (Berlin) 163:30–46

    Article  Google Scholar 

  • Butel JS (1972) Studies with human papilloma virus modeled after known papovavirus systems. J Natl Cancer Inst 48:285–299

    PubMed  Google Scholar 

  • Campo MS, Coggins LW (1982) Molecular cloning of bovine papillomavirus genomes and comparison of their sequence homologies by heteroduplex mapping. J Gen Virol 63:255–264

    PubMed  Google Scholar 

  • Campo MS, Spandidos DA (1983) Molecularly cloned bovine papillomavirus DNA transforms mouse fibroblasts in vitro. J Gen Virol 64:549–558

    PubMed  Google Scholar 

  • Campo MS, Moar MH, Jarrett WFH, Laird HM (1980) A new Papillomavirus associated with alimentary tract cancer in cattle. Nature (Lond) 286:180–182

    Article  PubMed  Google Scholar 

  • Campo MS, Moar MH, Laird HM, Jarrett WFH (1981) Molecular heterogeneity and lesion site specificity of cutaneous bovine papillomaviruses. Virology 113:323–335

    Article  PubMed  Google Scholar 

  • Campo MS, Spandidos DA, Lang J, Wilkie NM (1983) Transcriptional control signals in the genome of bovine papillomavirus type 1. Nature (Lond) 303:77–81

    Article  PubMed  Google Scholar 

  • Chen EY, Howley PM, Levinson AD, Seeburg PH (1982) The primary structure and genetic organization of the bovine papillomavirus type 1 genome. Nature (Lond) 299:529–534

    Article  PubMed  Google Scholar 

  • Cheville NF (1966) Studies on connective tissue tumors in the hamster produced by bovine papilloma virus. Cancer Res 26:2334–2339

    PubMed  Google Scholar 

  • Chretien JH, Esswein JG, Garagusi VF (1978) Decreased T cell levels in patients with warts. Arch Dermatol 114:213–215

    Article  PubMed  Google Scholar 

  • Ciuffo G (1907) Innesto positivo con filtrato di verrucae volgare. Giorn Ital Mal Venereol 48:12–17

    Google Scholar 

  • Clad A, Gissmann L, Meier B, Freese UK, Schwarz E (1982) Molecular cloning and partial nucleotide sequence of human papillomavirus type 1a DNA. Virology 118:254–259

    Article  PubMed  Google Scholar 

  • Coggin JR Jr, Zur Hausen H (1979) Workshop on papillomaviruses and cancer. Cancer Res 39:545–546

    Google Scholar 

  • Cohen JC (1980) Methylation of milk-borne and genetically transmitted mouse mammary tumor virus proviral DNA. Cell 19:653–663

    PubMed  Google Scholar 

  • Cook T, Cohn A, Brunschwig P, Goepfert H, Butel J, Rawls W (1973) Laryngeal papilloma: Etiologic and therapeutic considerations. Ann Otol Rhinol Laryngeol 82:649–655

    Google Scholar 

  • Costa J, Howley PM, Bowling MC, Howard R, Bauer WC (1981) Presence of human papilloma viral antigens in juvenile multiple laryngeal papilloma. Am J Clin Pathol 75:194–197

    PubMed  Google Scholar 

  • Crawford LV, Crawford EM (1963) A comparative study of polyoma and papilloma viruses. Virology 21:258–263

    Article  PubMed  Google Scholar 

  • Croissant O, Testaniere V, Orth G (1982) Mise en évidence et localisation de régions conservées dans les génomes du papillomavirus humain 1a et du papillomavirus bovin 1 par analyse d'“hétéroduplex” au microscope életronique. CR Seances Acad Sci III 294:581–586

    Google Scholar 

  • Cubie HA (1972) Serological studies in a student population prone to infection with human papilloma virus. J Hyg 70:677–690

    Google Scholar 

  • Cubie HA (1976) Failure to produce warts on human skin grafts on “nude” mice. Br J Dermatol 94:659–665

    PubMed  Google Scholar 

  • Danos O, Katinka M, Yaniv M (1980) Molecular cloning, refined physical map and heterogeneity of methylation sites of papilloma virus type 1a DNA. Eur J Biochem 109:457–461

    Article  PubMed  Google Scholar 

  • Danos O, Katinka M, Yaniv M (1982) Human papillomavirus 1a complete DNA sequence: A novel type of genome organization among papovaviridae. EMBO J 1:231–236

    PubMed  Google Scholar 

  • Della Torre G, Pilotti S, De Palo G, Rilke F (1978) Viral particles in cervical condylomatous lesions. Tumori 64:549–553

    PubMed  Google Scholar 

  • De Peuter M, De Clercq B, Minette A (1977) An epidemiological survey of virus warts of the hands among butchers. Br J Dermatol 96:427–431

    PubMed  Google Scholar 

  • Desrosiers RC, Mulder C, Fleckenstein B (1979) Methylation of Herpes-virus saimiri DNA in lymphoid tumor cell lines. Proc Natl Acad Sci USA 76:3839–3843

    PubMed  Google Scholar 

  • De Villiers EM, Gissmann L, Zur Hausen H (1981) Molecular cloning of viral DNA from human genital warts. J Virol 40:932–935

    PubMed  Google Scholar 

  • DiMaio D, Treisman R, Maniatis T (1982) Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells. Proc Natl Acad Sci USA 79:4030–4034

    PubMed  Google Scholar 

  • Dipaolo JA, Popescu NC (1979) Cytogenetics of Syrian hamster and its relationship to in vitro neoplastic transformation. Proc Exp Tumor Res 24:2–16

    Google Scholar 

  • Dürst M, Gissmann L, Ikenberg H, Zur Hausen H (1983) A new type of papillomavirus DNA from a cervical carcinoma and its prevalence in cancer biopsies from different geographic regions. Proc Natl Acad Sci USA 80:3812–1815

    PubMed  Google Scholar 

  • Dvoretzky I, Shober R, Chattopadhy SK, Lowy DR (1980) A quantitative in vitro focus forming assay for bovine papilloma virus. Virology 103:369–375

    Article  PubMed  Google Scholar 

  • Evans CA, Ito Y (1966) Antitumor immunity in the Shope papilloma-carcinoma complex of rabbits. III. Response to reinfection with viral nucleic acid. J Natl Cancer Inst 36:1161–1166

    PubMed  Google Scholar 

  • Evans CA, Gorman LR, Ito Y, Weiser RS (1962) Antitumor immunity in the SHOPE papilloma-carcinoma complex of rabbits. I. Papilloma regression induced by homologous and autologous tissue vaccines. J Natl Cancer Inst 29:277–285

    PubMed  Google Scholar 

  • Fatemi-Nainie S, Anderson LW, Cheevers WP (1982) Identification of a transforming retrovirus from cultured equine dermal fibrosarcoma. Virology 120:490–494

    Article  PubMed  Google Scholar 

  • Favre M, Breitburd F, Croissant O, Orth G (1974) Hemagglutinating activity of bovine papilloma virus. Virology 60:572–578

    Article  PubMed  Google Scholar 

  • Favre M, Breitburd F, Croissant O, Orth G (1975a) Structural polypeptides of rabbit, bovine, and human papilloma viruses. J Virol 15:1239–1247

    PubMed  Google Scholar 

  • Favre M, Orth G, Croissant O, Yanif M (1975b) Human papillomavirus DNA: physical map. Proc Natl Acad Sci USA 72:4810–4814

    PubMed  Google Scholar 

  • Favre M, Breitburd F, Croissant O, Orth G (1977) Chromatin-like structures obtained after alkaline disruption of bovine and human papillomaviruses. J Virol 21:1205–1209

    PubMed  Google Scholar 

  • Favre M, Jibard N, Orth G (1982) Restriction mapping and physical characterization of the cottontail rabbit papillomavirus genome in transplantable VX2 and VX7 domestic rabbit carcinomas. Virology 119:298–309

    Article  PubMed  Google Scholar 

  • Feldman YM, Nikital JA (1979) Condylomata acuminata. NY State J Med 1747–1749

    Google Scholar 

  • Finch JI, Klug A (1965) The structure of viruses of the papilloma-polyoma type. III. Structure of rabbit papilloma virus. J Mol Biol 13:1–12

    PubMed  Google Scholar 

  • Ford JN, Jennings PA, Spradbrow PB, Francis J (1982) Evidence for papillomaviruses in ocular lesions in cattle. Res Vet Sci 32:257–259

    PubMed  Google Scholar 

  • Freed DLJ, Eyres KE (1979) Persistent warts protected from immune attack by a blocking factor Br J Dermatol 100:731–733

    PubMed  Google Scholar 

  • Freese UK, Schulte P, Pfister H (1982) Papilloma virus-induced tumors contain a virus-specific transcript. Virology 117:257–261

    Article  PubMed  Google Scholar 

  • Friedewald WF, Kidd JG (1944) The recoverability of virus from papillomas produced therewith in domestic rabbits. J Exp Med 79:591–605

    Article  Google Scholar 

  • Friedmann JM, Fialkow PJ (1976) Viral “tumorigenesis” in man: Cell markers in condylomata acuminata. Int J Cancer 17:57–61

    PubMed  Google Scholar 

  • Friedman JC, Lewy JP, Lasneret J, Thomas M, Boiron M, Bernard J (1963) Induction de fibromes sous-cutanés chez le hamster doré par inoculation d'extraits à cellulaires de papillomes bovins. CR Seances Acad Sci III 257:2328

    Google Scholar 

  • Frithiof L, Wersäll J (1967) Virus-like particles in papillomas of the human oral cavity. Arch Virusforschung 21:31–44

    Article  Google Scholar 

  • Gamperl R, Amtmann E, Pfister H (1983) Chromosome abnormalities in bovine papillomavirus induced hamster tumors and transformed hamster cells. Cancer Res Clin Oncol 105:A37

    Google Scholar 

  • Genner J (1971) Verruca vulgaris. II. Demonstration of a complement fixation reaction. Acta Derm Venereol (Stockh) 51:365–373

    PubMed  Google Scholar 

  • Geraldes A (1969) Malignant transformation of hamster cells by cell-free extracts of bovine papillomas (in vitro). Nature 222:1283–1284

    PubMed  Google Scholar 

  • Geraldes A (1970) New antigens in hamster embryo cells transformed in vitro by bovine papilloma extracts. Nature 226:81–82

    Article  PubMed  Google Scholar 

  • Gissmann L, Zur Hausen H (1976) Human papilloma viruses: Physical mapping and genetic heterogeneity. Proc Natl Acad Sci USA 73:1310–1313

    PubMed  Google Scholar 

  • Gissmann L, Zur Hausen H (1977) Inverted repetitive sequences in human papilloma virus 1 (HPV 1) DNA. Virology 83:271–276

    Article  PubMed  Google Scholar 

  • Gissmann L, Zur Hausen H (1980) Partial characterization of viral DNA from human genital warts (condylomata acuminata). Int J Cancer 25:605–609

    PubMed  Google Scholar 

  • Gissmann L, Pfister H, Zur Hausen H (1977) Human papilloma viruses (HPV): Characterization of 4 different isolates. Virology 76:569–580

    Article  PubMed  Google Scholar 

  • Gissmann L, De Villiers EM, Zur Hausen H (1982a) Analysis of human genital warts (condylomata acuminata) and other genital tumors for human papilloma virus type 6 DNA. Int J Cancer 29:143–146

    PubMed  Google Scholar 

  • Gissmann L, Diehl V, Schultz-Coulon HJ, Zur Hausen H (1982b) Molecular cloning and characterization of human papilloma virus DNA derived from a laryngeal papilloma. J Virol 44:393–400

    PubMed  Google Scholar 

  • Gissmann L, Wolnik L, Ikenberg H, Koldovsky U. Schnürch HG, Zur Hausen H (1983) Human papillomavirus types 6 and 11 DNA sequences in genital and laryngeal papillomas and in some cervical cancers. Proc Natl Acad Sci USA 80:560–563

    PubMed  Google Scholar 

  • Glinski W, Jablonska S, Langner A, Obalek S, Haftek M, Proniewska M (1976) Cell-mediated immunity in epidermodysplasia verruciformis. Dermatologica 153:218–227

    PubMed  Google Scholar 

  • Glinski W, Obalek S, Jablonska S, Orth G (1981) T cell defect in patients with epidermodysplasia verruciformis due to human papillomavirus type 3 and 5. Dermatologica 162:141–147

    PubMed  Google Scholar 

  • Göbel U, Arnold W, Wahn VM, Treuner J, Jürgens H, Cantell K (1981) Comparison of human fibroblast and leukocyte interferon in the treatment of severe laryngeal papillomatosis in children. Eur J Pediatr 137:175–176

    PubMed  Google Scholar 

  • Goepfert H, Gutterman JU, Dichtel WJ, Sessions RB, Cangir A, Sulek M (1982) Leukocyte interferon in patients with juvenile laryngeal papillomatosis. Ann Otol Rhinol Laryngol 91:431–436

    PubMed  Google Scholar 

  • Green M, Orth G, Wold WSM, Sanders PR, Mackey JK, Favre M, Croissant O (1981) Analysis of human cancers, normal tissues, and verrucae plantares for DNA sequences of human papillomavirus types 1 and 2. Virology 110:176–184

    Article  PubMed  Google Scholar 

  • Green M, Brackmann KH, Sanders PR, Loewenstein PM, Freel JH, Eisinger M, Switlyk SA (1982) Isolation of a human papillomavirus from a patient with epidermodysplasia verruciformis: Presence of related viral DNA genomes in human urogenital tumors. Proc Natl Acad Sci USA 79:4437–4441

    PubMed  Google Scholar 

  • Greenberg MJH, Smith MTL, Katz RM (1973) Verrucae vulgaris rejection. A preliminary study of contact dermatitis and cellular immunity response. Arch Dermatol 107:580–582

    Article  PubMed  Google Scholar 

  • Gross G, Pfister H, Gissmann L, Hagedorn M (1982) Correlation between human papillomavirus type (HPV) and histology of warts. J Invest Dermatol 78:160–164

    Article  PubMed  Google Scholar 

  • Gross G, Pfister H, Hagedorn M, Stahn R (1983) Effect of oral aromatic retinoid (Ro 10-9359) on human papillomavirus 2 induced common warts. Dermatologica 166:48–53

    PubMed  Google Scholar 

  • Gross GE, Pfister H, Mittermayer C (1980) Papilloma virus particles in a fibroma of the tongue. Acta Derm Venereol (Stockh) 60:315–318

    PubMed  Google Scholar 

  • Gruss P, Dhar R, Khoury G (1981) Simian virus 40 tandem repeated sequences as an element of the early promoter. Proc Natl Acad Sci USA 78:943–947

    PubMed  Google Scholar 

  • Grussendorf EI (1980) Lichtmikroskopische Untersuchungen an typisierten Virus-warzen (HPV-1 und HPV-4). Arch Dermatol Res 268:141–148

    Article  PubMed  Google Scholar 

  • Grussendorf EI, Gahlen W (1975) Metaplasia of a verruca vulgaris into spinocellular carcinoma. Dermatologica 150:295–299

    PubMed  Google Scholar 

  • Grussendorf EI, Zur Hausen H (1979) Localization of viral DNA-replication in sections of human warts by nucleic acid hybridization with complementary RNA of human papilloma virus type 1. Arch Dermatol Res 264:55–63

    Article  PubMed  Google Scholar 

  • Haglund S, Lundquist PG, Cantell K, Strander H (1981) Interferon therapy in juvenile laryngeal papillomatosis. Arch Otolaryngol 107:327–332

    PubMed  Google Scholar 

  • Hayward WS, Neel BG, Astrin SM (1981) Activationof cellular oncogene by promoter insertion in ALV-induced lymphoid leukosis. Nature 290:475–480

    Article  PubMed  Google Scholar 

  • Heilman CA, Law MF, Israel MA, Howley PM (1980) Cloning of human papilloma virus genomic DNAs and analysis of homologous polynucleotide sequences. J Virol 36:395–407

    PubMed  Google Scholar 

  • Heilman CA, Engel L, Lowy DR, Howley PM (1982) Virus-specific transcription in bovine papillomavirus transformed mouse cells. Virology 119:22–34

    Article  PubMed  Google Scholar 

  • Hellström I, Evans CA, Hellström KE (1969) Cellular immunity and its serum-mediated inhibition in Shope-virus-induced rabbit papillomatosis. Int J Cancer 4:601–607

    PubMed  Google Scholar 

  • Hills E, Laverty CR (1979) Electron microscopic detection of papilloma virus particles in selected koilocytotic cells in a routine cervical smear. Acta Cytol 23:53–56

    PubMed  Google Scholar 

  • Howley PM, Law MF, Heilman C, Engel L, Alonso MC, Israel MA, Lowy DR, Lancaster WD (1980) Molecular characterization of papillomavirus genomes. Cold Spring Harbor Conf Cell Prolif 7:233–247

    Google Scholar 

  • Hoxtell EO, Mandel JS, Murray SS, Schuman LM, Goltz RW (1977) Incidence of skin carcinoma after renal transplantation. Arch Dermatol 113:436–438

    Article  PubMed  Google Scholar 

  • Ishimoto A, Ito Y (1969) Specific surface antigens in Shope papilloma cells. Virology 39:595–597

    Article  PubMed  Google Scholar 

  • Ishimoto A, Oota S, Kimura I, Miyake T, Ito Y (1970) In vitro cultivation and antigenicity of cottontail rabbit papilloma cells induced by the Shope papilloma virus. Cancer Res 30:2598–2605

    PubMed  Google Scholar 

  • Ito Y (1963) Studies on subviral tumorigenesis: carcinoma derived from nucleic acid-induced papillomas of rabbit skin. Acta Unio Int Contra Cancrum 19:280–283

    PubMed  Google Scholar 

  • Ito Y (1975) Papilloma-myxoma viruses. In: Becker FF (ed) Cancer, vol 2. Plenum Press, New York, pp 323–341

    Google Scholar 

  • Ito Y (1981) Effect of an aromatic retinoic acid analog (Ro 10-9359) on growth of virus-induced papilloma (Shope) and related neoplasia of rabbits. Eur J Cancer 17:35–42

    PubMed  Google Scholar 

  • Jablonska S, Biczysko W, Jakubowicz W, Dabrowski H (1970) The ultrastructure of transitional states to Bowen's disease and invasive Bowen's carcinoma in epidermodysplasia verruciformis. Dermatologica 140:186–194

    PubMed  Google Scholar 

  • Jablonska S, Dabrowski J, Jakubowicz K (1972) Epidermodysplasia verruciformis as a model in studies on the role of papova viruses in oncogenesis. Cancer Res 32:583–589

    PubMed  Google Scholar 

  • Jablonska S, Orth G, Jarzabek-Chorzelska M, Rzesa G, Obalek S, Glinski W, Favre M, Croissant O (1979) Epidermodysplasia verruciformis versus disseminated verrucae planae: Is epidermodysplasia verruciformis a generalized infection with wart virus? J Invest Dermatol 72:114–119

    Article  PubMed  Google Scholar 

  • Jablonska S, Orth G, Glinski G, Obalek S, Jarzabek-Chorzelska M, Croissant O, Favre M, Rzesa G (1980) Morphology and immunology of human warts and familial warts. In: Bachmann PA (ed) Leukaemias, lymphomas and papillomas: Comparative aspects. Taylor and Francis, London, pp 107–131

    Google Scholar 

  • Jablonska S, Obalek S, Wolska H, Jarzabek-Chorzelska M (1981) Ro 10-9359 in epidermodysplasia verruciformis. In: Orfanos CE, Braun-Falco O, Farber EM, Grupper Ch, Polano MK, Schuppli R (eds) Retinoids, advances in basic research and therapy. Springer, Berlin Heidelberg New York, pp 401–405

    Google Scholar 

  • Jablonska S, Obalek S, Orth G, Haftek M, Jarzabek-Chorzelska M (1982) Regression of the lesions of epidermodysplasia verruciformis. Br J Dermatol 107:109–116

    PubMed  Google Scholar 

  • Jacyk WK, Subbuswamy SG (1979) Epidermodysplasia verruciformis in Nigerians. Dermatologica 159:256–265

    PubMed  Google Scholar 

  • Jarrett WFH (1980) Bovine papillomaviruses and alimentary malignancy. In: Bachmann PA (ed) Leukaemia, lymphomas and papillomas: Comparative aspects. Taylor and Francis, London, pp 87–91

    Google Scholar 

  • Jarrett WFH, McNeil PE, Grimshaw WTR, Selman IE, McIntyre WIM (1978) High incidence area of cattle cancer with a possible interaction between an environmental carcinogen and a papilloma virus. Nature 274:215–217

    Article  PubMed  Google Scholar 

  • Jenson AB, Rosenthal JR, Olson C, Pass F, Lancaster WD, Shah K (1980) Immunological relatedness of papillomaviruses from different species. J Natl Cancer Inst 64:495–500

    PubMed  Google Scholar 

  • Kaufmann J, Meves C, Ott F (1978) Die Epidermodysplasia verruciformis Lewandowsky-Lutz in licht-und elektronenoptischem Vergleich mit den übrigen Papova-Virus-Akanthomen. Arch Dermatol Res 261:39–54

    Article  PubMed  Google Scholar 

  • Kidd JG (1938) The course of virus-induced rabbit papillomas as determined by virus cells and host. J Exp Med 67:551–574

    Article  Google Scholar 

  • Kidd JG, Rous P (1940) Cancers deriving from the virus papillomas of wild rabbits under natural conditions. J Exp Med 71:469–485

    Article  Google Scholar 

  • Kidd JG, Beard JW, Rous P (1936) Serological reactions with a virus causing a rabbit papilloma which becomes cancerous. II. Tests of the blood of animal carrying various tumors. J Exp Med 64:63–78

    Article  Google Scholar 

  • Kienzler J-L, Laurent R, Coppey J, Favre M, Orth G, Coupez L, Agache P (1979) tEpidermodysplasie verruciforme. Données ultrastructurales, virologiques et photobiologiques; à propos d'une observation. Ann Dermatol Venereol 106:549–563

    PubMed  Google Scholar 

  • Kimura S, Hirai A, Harada R, Nagashima M (1978) So-called multicentric pigmented Bowen's disease. Dermatologica 157:229–237

    PubMed  Google Scholar 

  • Kleinsasser O, Oliveira e Cruz G (1973) “Juvenile” und “adulte” Kehlkopfpapillome. HNO 21:97–106

    PubMed  Google Scholar 

  • Kleinschmidt AK, Kass SJ, Williams RC, Knight CA (1965) Cyclic DNA of Shope papilloma virus. J Mol Biol 13:749–756

    Google Scholar 

  • Klug A, Finch JT (1965) Structure of virus of the papilloma-polyoma type I. Human wart virus. J Mol Biol 11:403–423

    PubMed  Google Scholar 

  • Koller LD, Olson C (1972) Attempted transmission of warts from man, cattle, and horses, and of deer fibroma, to selected hosts. J Invest Dermatol 58:366–368

    Article  PubMed  Google Scholar 

  • Koranda FC, Dehmel EM, Kahn G, Penn I (1974) Cutaneous complications in immunosuppressed renal homograft recipients. JAMA 229:419–424

    Article  PubMed  Google Scholar 

  • Kreider JW (1963) Studies on the mechanism responsible for the spontaneous regression of the Shope rabbit papilloma. Cancer Res 23:1593–1599

    PubMed  Google Scholar 

  • Kreider JW (1980) Neoplastic progression of the Shope rabbit papilloma. Cold Spring Harbor Conf Cell Prolif 7:283–300

    Google Scholar 

  • Kremsdorf D, Jablonska S, Favre M, Orth G (1982) Biochemical characterization of two types of human papillomaviruses associated with epidermodysplasia verruciformis. J Virol 43:436–447

    PubMed  Google Scholar 

  • Krzyzek RA, Watts SL, Anderson DL, Faras AJ, Pass F (1980) Anogenital warts contain several distinct species of human papillomavirus. J Virol 36:236–244

    PubMed  Google Scholar 

  • Kurman RJ, Shah KH, Lancaster WD, Jenson AB (1981) Immunoperoxidase localization of papillomavirus antigens in cervical dysplasia and vulvar condylomas. Am J Obstet Gynecol 140:931–935

    PubMed  Google Scholar 

  • Kurman RJ, Sanz LE, Jenson AB, Perry S, Lancaster WD (1982) Papillomavirus infection of the cervix I. Correlation of histology with viral structural antigens and DNA sequences. Int J Gynecol Pathol 1:17–28

    PubMed  Google Scholar 

  • Lack EE, Jenson AB, Smith HG, Healy GB, Pass F, Vawter GF (1980) Immunoperoxidase localization of human papillomavirus in laryngeal papillomas. Intervirology 14:148–154

    PubMed  Google Scholar 

  • Lancaster WD (1979) Physical maps of bovine papillomavirus type 1 and type 2 genomes. J Virol 32:684–687

    PubMed  Google Scholar 

  • Lancaster WD (1981) Apparent lack of integration of bovine papillomavirus DNA in virus-induced equine and bovine tumors and virus-transformed mouse cells. Virology 108:251–255

    Article  PubMed  Google Scholar 

  • Lancaster WD, Jenson AB (1981) Evidence for papillomavirus antigens and DNA sequences in laryngeal papilloma. Intervirology 15:204–212

    PubMed  Google Scholar 

  • Lancaster WD, Meinke W (1975) Persistence of viral DNA in human cell cultures infected with human papilloma virus. Nature 256:434–436

    Article  PubMed  Google Scholar 

  • Lancaster WD, Olson C (1978) Demonstration of two distinct classes of bovine papilloma virus. Virology 89:371–379

    Article  Google Scholar 

  • Lancaster WD, Olson C (1980) State of bovine papilloma virus DNA in connective tissue tumors. Cold Spring Harbor Conf Cell Prolif 7:223–232

    Google Scholar 

  • Lancaster WD, Olson C (1982) Animal papillomaviruses. Microbiol Rev 46:191–207

    PubMed  Google Scholar 

  • Lancaster WD, Sundberg JP (1982) Characterization of papilloma viruses isolated from cutaneous fibromas of white-tailed deer and mule deer. Virology 123:212–216

    Article  PubMed  Google Scholar 

  • Lancaster WD, Olson C, Meinke W (1976) Quantitation of bovine papilloma viral DNA in viral-induced tumors. J Virol 17:824–831

    PubMed  Google Scholar 

  • Lancaster WD, Olson C, Meinke W (1977) Bovine papilloma virus: presence of virus-specific DNA sequences in naturally occurring equine tumors. Proc Natl Acad Sci USA 74:524–528

    PubMed  Google Scholar 

  • Lancaster WD, Theilen GH, Olson C (1979) Hybridization of bovine papilloma virus type 1 and type 2 DNA to DNA from virus-induced hamster tumors and naturally occurring equine connective tissue tumors. Intervirology 11:227–233

    PubMed  Google Scholar 

  • LaPorta RF, Taichman LB (1982) Human papilloma viral DNA replicates as a stable episome in cultured epidermal keratinocytes. Proc Natl Acad Sci USA 79:3393–3397

    PubMed  Google Scholar 

  • Laurent R, Coume-Marquet S, Kienzler JL, Lambert D, Agache P (1978) Comparative electron microscopic study of clear cells in epidermodysplasia verruciformis and flat warts. Arch Dermatol Res 263:1–12

    Article  Google Scholar 

  • Laverty CR, Russell P, Hills E, Booth N (1978) The significance of noncondylomatous wart virus infection of the cervical transformation zone. A review with discussion of two illustrative cases. Acta Cytol 22:195–201

    PubMed  Google Scholar 

  • Law M-F, Lancaster WD, Howley PM (1979) Conserved sequences among the genomes of papillomaviruses. J Virol 32:199–207

    PubMed  Google Scholar 

  • Law M-F, Lowy DR, Dvoretzky I, Howley PM (1981) Mouse cells transformed by bovine papillomavirus contain only extrachromosomal viral DNA sequences. Proc Natl Acad Sci USA 78:2727–2731

    PubMed  Google Scholar 

  • Law M-F, Howard B, Sarver N, Howley PM (1982) Expression of selective traits in mouse cells, transformed with a BPV DNA derived hybrid molecule containing E. coli gpt. In: Gluzman Y (ed) Eukaryotic viral vectors. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, pp 79–85

    Google Scholar 

  • Le Bouvier GL, Sussman M, Crawford LV (1966) Antigenic diversity of mammalian papillomaviruses. J Gen Microbiol 45:497–501

    Google Scholar 

  • Lecatsas G, Boes E (1979) Papillomavirus in pregnancy urine. Lancet II:533–534

    Article  Google Scholar 

  • Lee AKY, Eisinger M (1976) Cell-mediated immunity (CMI) to human wart virus and wart-associated tissue antigens. Clin Exp Immunol 26:419–424

    PubMed  Google Scholar 

  • Lewandowsky F, Lutz W (1922) Ein Fall einer bisher nicht beschriebenen Hauterkrankung (Epidermodysplasia verruciformis). Arch Dermatol Syph (Berlin) 141:193–203

    Article  Google Scholar 

  • Lowy DR, Dvoretzky I, Shober R, Law M-F, Engel L, Howley PM (1980) In vitro tumorigenic transformation by a defined subgenomic fragment of bovine papilloma virus DNA. Nature (Lond) 287:72–74

    Article  PubMed  Google Scholar 

  • Lusky M, Botchan M (1981) Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences. Nature 293:79–81

    Article  PubMed  Google Scholar 

  • Lusky M, Berg L, Botchan M (1982) Enhancement of tk transformation by sequences of bovine papilloma virus. In: Gluzman Y (ed) Eukaryotic viral vectors. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York

    Google Scholar 

  • Lutzner MA (1978) Epidermodysplasia verruciformis. Bull Cancer 65:169–182

    PubMed  Google Scholar 

  • Lutzner MA, Blanchet-Bardon C (1980) Oral retinoid treatment of human papillomavirus type 5-induced epidermodysplasia verruciformis. N Engl J Med 302:1091

    Google Scholar 

  • Lutzner M, Croissant O, Ducasse M-F, Kreis H, Crosnier J, Orth G (1980) A potentially oncogenic human papillomavirus (HPV-5) found in two renal allograft recipients. J Invest Dermatol 75:353–356

    Article  PubMed  Google Scholar 

  • Massing AM, Epstein WL (1963) Natural history of warts. A two-year study. Arch Dermatol 87:306

    PubMed  Google Scholar 

  • Matthews REF (1982) Classification and nomenclature of viruses. Intervirology 17:1–199

    PubMed  Google Scholar 

  • Matthews RS, Shirodaria PV (1973) Study of regressing warts by immunofluorescence. Lancet I:689–691

    Article  Google Scholar 

  • Mayer H, Bollag W, Hänni R, Rüegg R (1978) Retinoids, a new class of compounds with prophylactic and therapeutic activities in oncology and dermatology. Experientia 34:1105–1119

    Article  PubMed  Google Scholar 

  • McMichael H (1965) Inhibition of growth of Shope papilloma by hypervitaminosis A. Cancer Res 25:947–956

    PubMed  Google Scholar 

  • McMichael H (1967) Inhibition by methylprednisolone of regression of the Shope rabbit papilloma. J Natl Cancer Inst 39:55–65

    PubMed  Google Scholar 

  • McVay P, Fretz M, Wettstein F, Stevens J, Ito Y (1982) Integrated Shope virus DNA is present and transcribed in the transplantable rabbit tumour Vx-7. J Gen Virol 60:271–278

    PubMed  Google Scholar 

  • Meinke W, Meinke GC (1981) Isolation and characterization of the major capsid protein of bovine papilloma virus type 1. J Gen Virol 52:15–24

    PubMed  Google Scholar 

  • Meischke HRC (1979) In vitro transformation by bovine papilloma virus. J Gen Virol 43:471–487

    Google Scholar 

  • Meisels A, Morin C, Casas-Cordero M (1982) Human papillomavirus infection of the uterine cervix. Int J Gynecol Pathol 1:75–94

    PubMed  Google Scholar 

  • Moar MH, Campo MS, Laird HM, Jarrett WFH (1981a) Unintegrated viral DNA sequences in hamster tumor induced by bovine papilloma virus. J Virol 39:945–949

    PubMed  Google Scholar 

  • Moar MH, Campo MS, Laird H, Jarrett WFH (1981b) Persistence of nonintegrated viral DNA in bovine cells transformed in vitro by bovine papillomavirus type 2. Nature 293:749–751

    Article  PubMed  Google Scholar 

  • Moreno-Lopez J, Pettersson U, Dinter Z, Philipson L (1981) Characterization of a papilloma virus from the European elk (EEPV). Virology 112:589–595

    Article  PubMed  Google Scholar 

  • Morgan DM, Meinke W (1980) Isolation of clones of hamster embryo cells transformed by the bovine papilloma virus. Current Microbiology 3:247–251

    Google Scholar 

  • Morin C, Meisels A (1980) Human papilloma virus, infectin of the uterine cervix. Acta Cytol 24:82–84

    PubMed  Google Scholar 

  • Morin C, Braun L, Casas-Cordero M, Shah KV, Roy M, Fortier M, Meisels A (1981) Confirmation of the papillomavirus etiology of condylomatous cervix lesions by the peroxidase-antiperoxidase technique. J Natl Cancer Inst 66:831–834

    PubMed  Google Scholar 

  • Morison WL (1975a) Viral warts, herpes simplex and herpes zoster in patients with secondary immune deficiencies and neoplasms. Br J Dermatol 92:625–630

    PubMed  Google Scholar 

  • Morison WL (1975b) Cell-mediated immune response in patients with warts. Br J Dermatol 93:553–556

    PubMed  Google Scholar 

  • Morison WL (1975c) In vitro assay of immunity to human wart antigen. Br J Dermatol 93:545–551

    PubMed  Google Scholar 

  • Mounts P, Shah KV, Kashima H (1982) Viral etiology of juvenile-and adult-onset squamous papilloma of the larynx. Proc Natl Acad Sci USA 79:5425–5429

    PubMed  Google Scholar 

  • Müller H, Gissmann L (1978) Mastomys natalensis papilloma virus (MnPV), the causative agent of epithelial proliferations: Characterization of the virus particle. J Gen Virol 41:315–323

    PubMed  Google Scholar 

  • Mullen DL, Silverberg SG Penn I, Hammond WS (1976) Squamous cell carcinoma of the skin and lip in renal homograft recipients. Cancer 37:729–734

    PubMed  Google Scholar 

  • Murphy MF, Potter HL, Abraham JM, Morgan DM, Meinke WJ (1981) Analysis of a restriction endonuclease map for a rabbit papillomavirus DNA. Current Microbiology 5:349–352

    Article  Google Scholar 

  • Murray RF, Hobbs J, Payne B (1971) Possible clonal origin of common warts (verruca vulgaris). Nature (Lond) 232:51–52

    Article  PubMed  Google Scholar 

  • Nasseri M, Wettstein FO, Stevens JG (1982) Two colinear and spliced viral transcripts are present in non-virus-producing benign and malignant neoplasms induced by the Shope (rabbit) papilloma virus. J Virol 44:263–268

    PubMed  Google Scholar 

  • Noyes WF (1965) Structure of the human wart virus. Virology 23:65–72

    Article  Google Scholar 

  • Nürnberger F, Pfister H, Zur Hausen H (1981) Epidermodysplasia verruciformis bei einem Westafrikaner, verursacht durch einen bisher unbekannten Typ eines humanen Papillomavirus (HPV 8) — Versuch einer oralen Retinoidbehandlung. Hautarzt 32 (Suppl V):480

    Google Scholar 

  • Obalek S, Glinski W, Haftek M, Orth G, Jablonska S (1980) Comparative studies on cell-mediated immunity in patients with different warts. Dermatologica 161:73–83

    PubMed  Google Scholar 

  • Ogilvie MM (1970) Serological studies with human papova (wart) virus. J Hyg 68:479–483

    Google Scholar 

  • Oguchi M, Komura J, Tagami H, Ofuji S (1981a) Ultrastructural studies of spontaneously regressing plane warts. Langerhans cells show marked activation. Arch Dermatol Res 271:55–61

    Article  PubMed  Google Scholar 

  • Oguchi M, Komura J, Tagami H, Ofuji S (1981b) Ultrastructural studies of spontaneously regressing plane warts. Macrophages attack verruca-epidermal cells. Arch Dermatol Res 270:403–411

    Article  PubMed  Google Scholar 

  • Olson C, Cook RH (1951) Cutaneous sarcoma-like lesions of the horse caused by the agent of bovine papilloma. Proc Soc Exp Biol Med 77:281–284

    PubMed  Google Scholar 

  • Olson C, Gordon DE, Robl MG, Lee KP (1969) Oncogenicity of bovine papilloma virus. Arch Environ Health 19:827–837

    PubMed  Google Scholar 

  • Orfanos CE, Strunk W, Gartmann H (1974) Fokale epitheliale Hyperplasie der Mundschleimhaut: Hecksche Krankheit. Dermatologica 149:163–175

    PubMed  Google Scholar 

  • Oriel JD (1971a) Natural history of genital warts. Br J Vener Dis 47:1–8

    PubMed  Google Scholar 

  • Oriel JD (1971b) Anal warts and anal coitus. Br J Vener Dis 47:373–376

    PubMed  Google Scholar 

  • Orth G, Croissant O (1968) Charactères des cultures de première explantation de cellules de papillomes provoqués par le virus de Shope chez le lapin domestique. CR Seances Acad Sci III 266:1084–1087

    Google Scholar 

  • Orth G, Jeanteur P, Croissant O (1971) Evidence for localization of vegetative viral DNA replication by autoradiographic detection of RNA-DNA hybrids in sections of tumors induced by Shope papilloma virus. Proc Natl Acad Sci USA 68:1876–1880

    PubMed  Google Scholar 

  • Orth G, Favre M, Croissant O (1977) Characterization of a new type of human papilloma virus that causes skin warts. J Virol 24:108–120

    PubMed  Google Scholar 

  • Orth G, Breitburd F, Favre M (1978a) Evidence for antigenic determination shared by the structural polypeptides of (Shope) rabbit papillomavirus and human papillomavirus type 1. Virology 91:243–255

    Article  PubMed  Google Scholar 

  • Orth G, Jablonska S, Favre M, Croissant O, Jarzabek-Chorzelska M, Rzesa G (1978b) Characterization of two new types of human papilloma viruses in lesions of epidermodysplasia verruciformis. Proc Natl Acad Sci USA 75:1537–1541

    PubMed  Google Scholar 

  • Orth G, Jablonska S, Jarzabek-Chorzelska M, Obalek S, Rzesa G, Favre M, Croissant O (1979) Characteristics of the lesions and risk of malignant conversion associated with the type of human papillomavirus involved in epidermodysplasia verruciformis. Cancer Res 39:1074–1082

    PubMed  Google Scholar 

  • Orth G, Favre M, Breitburd F, Croissant O, Jablonska S, Obalek S, Jarzabek-Chorzelska M, Rzesa G (1980) Epidermodysplasia verruciformis: A model for the role of papilloma viruses in human cancer. Cold Spring Harbor Conf Cell Prolif 7:259–282

    Google Scholar 

  • Orth G, Jablonska S, Favre M, Croissant O, Obalek S, Jarzabek-Chorzelska M, Jibard N (1981) Identification of papillomaviruses in butcher's warts. J Invest Dermatol 76:97–102

    Article  PubMed  Google Scholar 

  • Osterhaus AMDE, Ellens DJ, Horzinek MC (1977) Identification and characterization of a papillomavirus from birds (Fringillidae). Intervirology 8:351–359

    PubMed  Google Scholar 

  • Ostrow RS, Krzyzek R, Pass F, Faras AJ (1981) Identification of a novel human papilloma virus in cutaneous warts of meat handlers. Virology 108:21–27

    PubMed  Google Scholar 

  • Ostrow RS, Bender M, Niimura M, Seki T, Kawashima M, Pass F, Faras AJ (1982) Human papillomavirus DNA in cutaneous primary and metastasized squamous cell carcinomas from patients with epidermodysplasia verruciformis. Proc Natl Acad Sci USA 79:1634–1638

    PubMed  Google Scholar 

  • Parsons RJ, Kidd JG (1942) Oral papillomatosis of rabbits: A virus disease. J Exp Med 77:233–250

    Article  Google Scholar 

  • Pass F, Maizel JV (1973) Wart-associated antigens. II. Human immunity to viral structural proteins. J Invest Dermatol 60:307–311

    Article  Google Scholar 

  • Pass F, Marcus DM (1973) Wart-associated antigens. I. Isolation of tissue antigens using antibody immunoadsorbents. J Invest Dermatol 60:301–306

    Article  Google Scholar 

  • Pass F, Niimura M, Kreider JW (1973) Prolonged survival of human skin xenografts on antithymocyte serum-treated mice: failure to produce verrucae by inoculation with extracts of human warts. J Invest Dermatol 61:371–374

    Article  PubMed  Google Scholar 

  • Pathak S, Hsu TC, Trentin JJ, Butel JS, Panigrahy B (1981) Nonrandom chromosome abnormalities in transformed syrian hamster cell lines. In: Arrighi FE, Rao PN, Stubblefield E (eds) Genes, chromosomes and neoplasia. Raven Press, New York, pp 405–417

    Google Scholar 

  • Perry TL, Harman L (1974) Warts in diseases with immune defects. Cutis 13:359–362

    Google Scholar 

  • Petzoldt D, Pfister H (1980) HPV 1 DNA in lesions of focal epithelial hyperplasia Heck. Arch Dermatol Res 268:313–314

    Article  PubMed  Google Scholar 

  • Pfister H (1980) Comparative aspects of papillomatosis. In: Bachmann PA (ed) Leukaemias, lymphomas and papillomas: Comparative aspects. Taylor and Francis, London, pp 93–106

    Google Scholar 

  • Pfister H, Meszaros J (1980) Partial characterization of a canine oral papillomavirus. Virology 104:243–246

    Article  PubMed  Google Scholar 

  • Pfister H, Zur Hausen H (1978a) Characterization of proteins of human papilloma viruses (HPV) and antibody response to HPV 1. Med Microbiol Immunol 166:13–19

    Article  PubMed  Google Scholar 

  • Pfister H, Zur Hausen H (1978b) Seroepidemiological studies of human papilloma virus (HPV 1) infections. Int J Cancer 21:161–165

    PubMed  Google Scholar 

  • Pfister H, Gissmann L, Zur Hausen H (1977) Partial characterization of proteins of human papilloma viruses (HPV) 1–3. Virology 83:131–137

    Article  Google Scholar 

  • Pfister H, Gross G, Hagedorn M (1979a) Characterization of human papillomavirus 3 in warts of a renal allograft patient. J Invest Dermatol 73:349–353

    Article  PubMed  Google Scholar 

  • Pfister H, Huchthausen B, Gross G, Zur Hausen H (1979b) Seroepidemiological studies of bovine papillomavirus infections. J Natl Cancer Inst 62:1423–1425

    PubMed  Google Scholar 

  • Pfister H, Linz U, Gissmann L, Huchthausen B, Hoffmann D, Zur Hausen H (1979c) Partial characterization of a new type of bovine papillomaviruses. Virology 96:1–8

    Article  PubMed  Google Scholar 

  • Pfister H, Gissmann H, Zur Hausen H, Gross G (1980) Characterization of human and bovine papilloma viruses and of the humoral immune response to papilloma virus infection. Cold Spring Harbor Conf Cell Prolif 7:249–258

    Google Scholar 

  • Pfister H, Fink B, Thomas C (1981a) Extrachromosomal bovine papillomavirus type 1 DNA in hamster fibromas and fibrosarcomas. Virology 115:414–418

    Article  PubMed  Google Scholar 

  • Pfister H, Nürnberger F, Gissmann L, Zur Hausen H (1981b) Characterization of a human papillomavirus from epidermodysplasia verruciformis lesions of a patient from Upper Volta. Int J Cancer 27:645–650

    PubMed  Google Scholar 

  • Pfister H, Gassenmaier A, Nürnberger F, Stüttgen G (1983a) HPV 5 DNA in a carcinoma of epidermodysplasia verruciformis patient infected with various human papillomavirus types. Cancer Res 43:1436–1441

    PubMed  Google Scholar 

  • Pfister H, Hettich I, Runne U, Gissmann L, Chilf GN (1983b) Characterization of human papillomavirus type 13 from lesions of focal epithelial hyperplasia Heck. J Virol 47:363–366

    PubMed  Google Scholar 

  • Prawer SE, Pass F, Vance JC, Greenberg LJ, Yunis EJ, Zelickson AS (1977) Depressed immune functions in epidermodysplasia verruciformis. Arch Dermatol 113:495–499

    Article  PubMed  Google Scholar 

  • Puget A, Favre M, Orth G (1975) Induction de tumeurs fibroplastiques cutanées où sous-cutanées chez l'ochotone afghan (Ochotono rufescens rufescens) par inoculation du virus du papillome bovin. CR Seances Acad Sci III 280:2813–2816

    Google Scholar 

  • Pyrhönen S (1978) Human wart antibodies in patients with genital and skin warts. Acta Derm Venereol (Stockh) 58:427–432

    PubMed  Google Scholar 

  • Pyrhönen S, Johansson E (1975) Regression of warts. An immunological study. Lancet I:592–596

    Article  Google Scholar 

  • Pyrhönen S, Penttinen K (1972) Wart virus antibodies and the prognosis of wart disease. Lancet II:1330–1332

    Article  Google Scholar 

  • Rangan SRS, Gutter A, Baskin GB, Anderson D (1980) Virus associated papillomas in colobus monkeys (Colobus guereza). Lab Anim Sci 30(5):885–889

    PubMed  Google Scholar 

  • Rattanapanone V, Tashiro S, Tokuda H, Rattanapanone N, Ito Y (1981) Cellular retinoic acid-binding protein in virus-induced Shope papillomas of rabbit skin. Cancer Res 41:1483–1487

    PubMed  Google Scholar 

  • Reid TMS, Fraser NG, Kernohan IR (1976) Generalized warts and immune deficiency. Br J Dermatol 95:559–564

    PubMed  Google Scholar 

  • Reinacher M, Müller H, Thiel W, Rudolph RL (1978) Localization of papillomavirus and virus-specific antigens in the skin of tumor-bearing Mastomys natalensis (GRA Giessen). Med Microbiol Immunol 165:93–99

    Article  PubMed  Google Scholar 

  • Rheinwald JG, Green H (1975) Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. Cell 6:331–344

    Article  PubMed  Google Scholar 

  • Robl MG, Olson C (1968) Oncogenic action of bovine papilloma virus in hamsters. Cancer Res 28:1596–1604

    PubMed  Google Scholar 

  • Rogers S, Rous P (1951) Joint action of a chemical carcinogen and a neoplastic virus to induce cancer in rabbits. Results of exposing epidermal cells to a carcinogenic hydrocarbon at time of infection with the Shope papilloma virus. J Exp Med 93:459–488

    Article  PubMed  Google Scholar 

  • Rogers S, Kidd JG, Rous P (1960) Relationships of the Shope papilloma virus to cancers it determines in domestic rabbits. Acta Unio Int Contra Cancrum 16:129–130

    PubMed  Google Scholar 

  • Rotkin ID (1973) A comparison review of key epidemiological studies in cervical cancer related to current searches for transmissible agents. Cancer Res 33:1353–1367

    PubMed  Google Scholar 

  • Rous P, Beard JW (1934) A virus-induced mammalian growth with the characters of a tumor (the Shope rabbit papilloma). J Exp Med 60:701–722

    Article  Google Scholar 

  • Rous P, Beard JW (1935) The progression to carcinoma of virus-induced rabbit papillomas (Shope). J Exp Med 65:523–548

    Article  Google Scholar 

  • Rous P, Friedewald WF (1944) The effect of chemical carcinogens on virus-induced rabbit papillomas. J Exp Med 79:511–537

    Article  Google Scholar 

  • Rous P, Kidd JG (1938) The carcinogenic effect of a papilloma virus on the tarred skin of rabbits. I. Description of the phenomenon. J Exp Med 67:399–422

    Article  Google Scholar 

  • Rowson KEK, Mahy BWJ (1967) Human papova (wart) virus. Bacteriol Rev 31:110–131

    PubMed  Google Scholar 

  • Ruiter M, van Mullem PJ (1970) Behaviour of virus in malignant degeneration of skin lesions in epidermodysplasia verruciformis. J Invest Dermatol 54:324–331

    Article  PubMed  Google Scholar 

  • Rulison RH (1942) Warts. A statistical study of nine hundred twenty-one cases. Arch Dermatol Syphilol 46:66–81

    Google Scholar 

  • Sarver N, Gruss P, Law MF, Khoury G, Howley PM (1981) Bovine papilloma virus deoxyribonucleic acid: a novel eucaryotic cloning vector. Mol Cell Biol 1:486–496

    PubMed  Google Scholar 

  • Sarver N, Byrne JC, Howley PM (1982) Transformation and replication in mouse cells of a bovine papillomavirus-pML2 plasmid vector that can be rescued in bacteria. Proc Natl Acad Sci USA 79:7147–7151

    PubMed  Google Scholar 

  • Schaffhausen BS, Benjamin TL (1976) Deficiency in histone acetylation in nontransforming host range mutants of polyoma virus. Proc Natl Acad Sci USA 73:1092–1096

    PubMed  Google Scholar 

  • Schmauz R, Owor R (1980) Epidemiology of malignant degeneration of condylomata acuminata in Uganda. Pathol Res Pract 170:91–103

    Google Scholar 

  • Schwarz et al. (to be published) Nucleotide sequence of HPV 6 B-DNA.

    Google Scholar 

  • Seski JC, Reinhalter ER, Silva J Jr (1977) Abnormalities of lymphocyte transformations in women with condylomata acuminata. Obstet Gynecol 51:188–192

    Google Scholar 

  • Seto A, Notake K, Kawanishi M, Ito Y (1977) Development and regression of Shope papillomas induced in newborn domestic rabbits. Proc Soc Exp Biol Med 156:64–67

    PubMed  Google Scholar 

  • Shah KH, Lewis MG, Jenson AB, Kurman RJ, Lancaster WD (1980) Papillomavirus and cervical dysplasia. Lancet II:1190

    Article  Google Scholar 

  • Shelley WB, Wood MG (1981) Transformation of the common wart into squamous cell carcinoma in a patient with primary lymphedema. Cancer 48:820–824

    PubMed  Google Scholar 

  • Shirodaria PV, Matthews RS (1975) An immunofluorescence study of warts. Clin Exp Immunol 21:329–338

    PubMed  Google Scholar 

  • Shope RE, Mangold R, McNamara LG, Dumbell KR (1958) An infectious cutaneous fibroma of the Virginia white-tailed deer (Odocoileus virginianus). J Exp Med 108:797–802

    Article  PubMed  Google Scholar 

  • Siegel SE, Isaacs H Jr, Cohen SR, Stanley P (1979) Malignant transformation of tracheobronchial juvenile papillomatosis without prior radiotherapy. Ann Otol Rhinol Laryngol 88:192–197

    PubMed  Google Scholar 

  • Spencer ES, Andersen HK (1970) Clinically evident non-terminal infections with herpesviruses and the wart virus in immunosuppressed renal allograft patients. Br Med J III:251–254

    Google Scholar 

  • Spradbrow PB, Hoffmann D (1980) Bovine ocular squamous cell carcinoma. Vet Bull 50:449–459

    Google Scholar 

  • Spradbrow PB, Beardmore GL, Francis J (1983) Virions resembling papillomaviruses in hyperkeratotic lesions from sun-damaged skin. Lancet I:189

    Article  Google Scholar 

  • Starzl TE, Porter KA, Andres G, Halgrimson CG, Hurwitz R, Giles G, Terasaki PJ, Penn J, Schroter GT, Lilly J, Starkie SJ, Putnam CW (1970) Long-term survival after renal transplantation in humans. Ann Surg 172:437–472

    PubMed  Google Scholar 

  • Steigleder GK (1978) Histology of benign virus induced tumors of the skin. J Cutan Pathol 5:45–52

    PubMed  Google Scholar 

  • Stevens JG, Wettstein FO (1979) Multiple copies of Shope virus DNA are present in cells of benign and malignant non-virus-producing neoplasms. J Virol 30:891–898

    PubMed  Google Scholar 

  • Strauss MJ, Bunting H, Melnick JL (1950) Virus-like particles and inclusion bodies in skin papillomas. J Invest Dermatol 15:433–443

    PubMed  Google Scholar 

  • Sundberg JP, Russell WC, Lancaster W (1981) Papillomatosis in Indian elephants. JAMA 179:1247–1248

    Google Scholar 

  • Syrjänen KJ (1979) Morphologic survey of the condylomatous lesions in dysplastic and neoplastic epithelium of the uterine cervix. Arch Gynecol 227:153–161

    Article  PubMed  Google Scholar 

  • Syrjänen KJ (1980) Bronchial squamous cell carcinomas associated with epithelial changes identical to condylomatous lesions of the uterine cervix. Lung 158:131–142

    PubMed  Google Scholar 

  • Syrjänen KJ (1982) Histological changes identical to those of condylomatous lesions found in esophageal squamous cell carcinomas. Arch Geschwulstforsch 52:383–392

    Google Scholar 

  • Syverton JT (1952) The pathogenesis of the rabbit papilloma-to-carcinoma sequence. Ann NY Acad Sci 54:1126–1140

    PubMed  Google Scholar 

  • Tagami H, Takigawa M, Ogino A, Imamura S, Ofugi S (1977) Spontaneous regression of plane warts after inflammation. Arch Dermatol 113:1209–1213

    Article  PubMed  Google Scholar 

  • Takigawa M, Tagami H, Watanabe S, Ogino A, Imamura S, Ofugi S (1977) Recovery processes during regression of plane warts. Arch Dermatol 113:1214–1218

    Article  PubMed  Google Scholar 

  • Thivolet J, Viac J (1978) Immunologie des verrues humaines. Ann Dermatol Venereol (Paris) 105:257–264

    PubMed  Google Scholar 

  • Thomas M, Levy JP, Tanzer J, Boiron M, Bernard J (1963) Transformation in vitro de cellules de peau de veau embryonnaire sous l'action d'extrants a cellulaires de papillomes bovins. CR Seances Acad Sci III 257:2155–2158

    Google Scholar 

  • Thomas M, Boiron M, Tanzer J, Levy JP, Bernard J (1964) In vitro transformation of mice cells by bovine papilloma virus. Nature (Lond) 202:709–710

    PubMed  Google Scholar 

  • Tooze J (1980) DNA tumor viruses. Molecular biology of tumor viruses, part 2. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York

    Google Scholar 

  • Turek LP, Byrne JC, Lowy DR, Dvoretzky I, Friedman RM, Howley PM (1982) Interferon induces morphologic reversion with elimination of extrachromosomal viral genomes in bovine papillomavirus-transformed mouse cells. Proc Natl Acad Sci USA 79:7914–7918

    PubMed  Google Scholar 

  • Vanselow BA, Spradbrow PB (1982) Papillomaviruses, papillomas and squamous cell carcinomas in sheep. Vet Rec 110:561–562

    PubMed  Google Scholar 

  • van Wyk CW (1977) Focal epithelial hyperplasia of the mouth: recently discovered in South Africa, Br J Dermatol 96:381–388

    PubMed  Google Scholar 

  • Viac J, Thivolet J, Chardonnet Y (1977a) Specific immunity in patients suffering from recurring warts before and after repetitive intradermal tests with human papilloma virus. Br J Dermatol 97:365–370

    PubMed  Google Scholar 

  • Viac J, Thivolet J, Hegazy MR, Chardonnet Y, Dambuyant C (1977b) Comparative study of delayed hypersensitivity skin reactions and antibodies to human papilloma virus (HPV). Clin Exp Immunol 29:240–246

    PubMed  Google Scholar 

  • Viac J, Schmitt D, Thivolet J (1978) An immunoelectron microscopic localization of wart associated antigens present in human papilloma virus (HPV) infected cells. J Invest Dermatol 70:263–266

    Article  PubMed  Google Scholar 

  • Ward M, Le Roux A, Small WP, Sircus W (1977) Malignant lymphoma and extensive viral wart formation in a patient with intestinal lymphangiectasia and lymphocyte depletion. Postgrad Med J 53:753–757

    PubMed  Google Scholar 

  • Wettstein FO, Stevens JG (1980) Distribution and state of viral nucleic acid in tumors induced by Shope papilloma virus. Cold Spring Harbor Conf Cell Prolif 7:301–307

    Google Scholar 

  • Wettstein FO, Stevens JG (1981) Transcription of the viral genome in papillomas and carcinomas induced by the Shope virus. Virology 109:448–451

    Article  PubMed  Google Scholar 

  • Wettstein FO, Stevens JG (1982) Variable-sized free episomes of Shope Papilloma virus DNA are present in all non-virus-producing neoplasms and integrated episomes are detected in some. Proc Natl Acad Sci USA 79:790–794

    PubMed  Google Scholar 

  • Woodruff JD, Braun L, Cavallieri R, Gupta P, Pass F, Shah KV (1980) Immunological identification of papillomavirus antigen in paraffin-processed condyloma tissues from the female genital tract. Obstet Gynecol 56:727–732

    PubMed  Google Scholar 

  • Yabe Y, Sadakane H, Isono H (1979) Connection between capsomeres in human papilloma virus. Virology 96:547–552

    Article  PubMed  Google Scholar 

  • Yoshiike K, Defendi V (1977) Presence of deletion molecules in human wart virus DNA. J Virol 21:415–418

    PubMed  Google Scholar 

  • Zachow KR, Ostrow RS, Bender M, Watts S, Okagaki T, Pass F, Faras AJ (1982) Detection of human papillomavirus DNA in anogenital neoplasias. Nature 300:771–773

    Article  PubMed  Google Scholar 

  • Zur Hausen H (1976) Condylomata acuminata and human genital cancer. Cancer Res 36:530

    Google Scholar 

  • Zur Hausen H (1977a) Human papilloma viruses and their possible role in squamous cell carcinomas. Curr Top Microbiol Immunol 78:1–30

    PubMed  Google Scholar 

  • Zur Hausen H (1977b) Cell-virus gene balance hypothesis of carcinogenesis. Behring Inst Mitt 61:23–30

    Google Scholar 

  • Zur Hausen H, Gissmann L, Steiner W, Dippold W, Dregger I (1975) Human papilloma virus and cancer. Bibl Haematologica 43:569–571

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institut für Klinische Virologie, Loschgestraße 7, 8520, Erlangen, FRG

    Herbert Pfister

Authors
  1. Herbert Pfister
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 1984 Springer-Verlag

About this chapter

Cite this chapter

Pfister, H. (1984). Biology and biochemistry of papillomaviruses. In: Reviews of Physiology, Biochemistry and Pharmacology, Volume 99. Reviews of Physiology, Biochemistry and Pharmacology, vol 99. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0027716

Download citation

  • DOI: https://doi.org/10.1007/BFb0027716

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-12989-9

  • Online ISBN: 978-3-540-38815-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation