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Prostaglandins and the lung

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Abstract

The series 2 prostaglandins and thromboxane A2 are synthesized by human lung tissue. When inhaled or infused, prostaglandins exert marked effects on both the airways and the pulmonary circulation. Increases in prostaglandin and thromboxane A2 synthesis occur in asthma, the adult respiratory distress syndrome, and pulmonary hypertension and are implicated as causes of these disorders. Inhibition of prostaglandin synthesis may improve or worsen asthma.

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  1. Respiratory Medicine Unit, City Hospital, Hucknall Road, NG5 1PB, Nottingham, England

    Simon P. Hanley

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Hanley, S.P. Prostaglandins and the lung. Lung 164, 65–77 (1986). https://doi.org/10.1007/BF02713630

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