Abstract
It is necessary to take enough calcium (Ca) for prevention of osteoporosis. In most cases nutrient intake has been sufficient in Japan. However, it was found that Ca intake, in particular, was insufficient according to the national nutrition survey conducted by the Ministry of Health and Welfare. This suggests that adequate intake of Ca from normal daily diet is difficult. Recently there have been a great deal of studies about the development of Ca sources.
In this study, three experiments were carried out to examine the effect of “AA Ca (Active Absorbable Calcium)” on bone metabolism in ovariectomized young and old rats. Five-week-old SD-strain female rats, seven-month-old Wistar-strain femalle rats, and eleven-month-old Wistar-strain female rats were ovariectomized and were fed a low Ca diet for approximately the one month. Thereafter within each experiment, all the rats were divided into two groups; a control group was fed a CaCO3 diet (0.3% Ca, 0.3% P) and an experimental AA Ca group was fed an AA Ca dietad libitum during the experimental period.
The results were as follows: in comparison with the CaCO3 group, the AA Ca group within each experiment,
1 the bone mineral density (BMD) of tibias measured using DXA (Hologic's QDR-1000) had significantly increased;
2 the breaking force of femurs had shown an increase; and
3 the intestinal Ca absorption was high.
These results suggest the “AA Ca” is effective in increasing the BMD, the breaking force, and the intestinal Ca absorption at every stage of development. The AA Ca could be regarded as a valuable, effective source of Ca in the prevention of osteoporosis.
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Omi, N., Ezawa, l. The effect of “AA Ca (active absorbable calcium)” on bone metabolism of ovariectomized rats. J Bone Miner Metab 11, S33–S40 (1993). https://doi.org/10.1007/BF02383539
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DOI: https://doi.org/10.1007/BF02383539