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The location of the ring C hydroxyl group in fusidic acid

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Zusammenfassung

Durch Herstellung der zwei Verbindungen IX und XI wurde erwiesen, dass die Hydroxylgruppe im Ring C der Fusidinsäure an C11 haften muss. Daraus sowie aus früheren Experimenten1 lässt sich für die Fusidinsäure die revidierte Konstitutionsformel XII ableiten.

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References

  1. W. O. Godtfredsen andS. Vangedal, Tetrahedron18, 1029 (1962).

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  2. R. Freeman andD. Whiffen, Mol. phys.4, 321 (1961).

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Authors and Affiliations

  1. Organisch-chemisches Laboratorium der Eidg, Technischen Hochschule, Zürich, Switzerland

    D. Arigoni & Andrée Marquet

  2. Leo Pharmaceutical Products, Copenhagen, Denmark

    W. von Daehne & W. O. Godtfredsen

  3. Varian AG Research Laboratories, Zürich, Switzerland

    A. Melera

Authors
  1. D. Arigoni
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  2. W. von Daehne
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  3. W. O. Godtfredsen
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  4. Andrée Marquet
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  5. A. Melera
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Arigoni, D., von Daehne, W., Godtfredsen, W.O. et al. The location of the ring C hydroxyl group in fusidic acid. Experientia 19, 521–522 (1963). https://doi.org/10.1007/BF02150888

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  • DOI: https://doi.org/10.1007/BF02150888

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