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Studies on the effect of fenbufen and sulindac on type II collagen-induced arthritis in rats

  • Immunosupression and Inflammation
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Abstract

The effects of fenbufen and sulindac, two novel antiinflammatory agents, on the developing and established lesion of type II collagen arthritis was investigated. Using paw diameter and radiology as parameters, these studies suggest that fenbufen is more efficacious than sulindac in this model.

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Authors and Affiliations

  1. Connective Tissue and Arthritis Research Unit, Metabolic Disease Research Section, Medical Research Division, American Cyanamid Company, Lederle Laboratories, 10965, Pearl River, New York, USA

    S. S. Kerwar & A. E. Sloboda

Authors
  1. S. S. Kerwar
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  2. A. E. Sloboda
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Kerwar, S.S., Sloboda, A.E. Studies on the effect of fenbufen and sulindac on type II collagen-induced arthritis in rats. Agents and Actions 12, 216–220 (1982). https://doi.org/10.1007/BF01965149

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  • DOI: https://doi.org/10.1007/BF01965149

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