Abstract
To evaluate the bone mass by bone density measurements in patients with distal radius fracture, a prospective open case-control study was carried out in the county of Uppsala, Sweden, with population-based cases and controls. There were 111 patients with a distal radius fracture who were otherwise healthy and aged 53–76 years, together with 60 healthy controls of similar age, sex and menopausal status. The main outcome measures were bone mineral density (BMD) in the lumbar spine and hip measured with dual-energy X-ray absorptiometry, and in the (non-fractured) distal forearm determined by single-photon absorptiometry. It was found that at all measuring sites BMD was significantly lower in cases than in controls. The difference in the distal forearm was around 20% (p<0.001) and in the spine and hip 5%–8% (p<0.05–0.001). In the healthy subjects there were positive correlations (r=0.39–0.65;p<0.002) between the forearm BMD and that of both the spine and hip, whereas in the patients with distal radius fracture there was only a weak correlation between the forearm and spine BMD (r=0.28;p<0.05) and no association between the BMD of the forearm and hip (r<0.01). It is concluded that patients with distal radius fracture who are otherwise healthy have a preferential bone loss at the distal forearm but also a generally low bone mass. Patients with fracture of the distal radius fracture should be considered for prophylactic measures against osteoporosis.
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Mallmin, H., Ljunghall, S. Distal radius fracture is an early sign of general osteoporosis: Bone mass measurements in a population-based study. Osteoporosis Int 4, 357–361 (1994). https://doi.org/10.1007/BF01622198
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DOI: https://doi.org/10.1007/BF01622198