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Ipriflavone influences the osteoblastic phenotype in Vitro

  • Session XI: Treatment: Fluoride, Bisphosphonates, Anabolic Steroids And New Developments
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References

  1. Willaman JJ. Some biological effects of flavonoids. J Am Pharm Assoc 1955;44:404–7.

    Google Scholar 

  2. Benvenuti S, Tanini A, Frediani U, et al. Effects of ipriflavone and its metabolites on a clonal osteoblastic cell line. J Bone Miner Res 1991;6:987–96.

    Google Scholar 

  3. Bradbury RB, White DE. Estrogens and related substances in plants. Vitam Horm 1955;12:207–33.

    Google Scholar 

  4. Bickoff EM, Livingston AL, Hendrickson AP, Booth AN. Relative potencies of several estrogenlike compounds found in forages. Agric Food Chem 1962;10:410–12.

    Google Scholar 

  5. Shutt DA, Cox RI. Steroid and phytoestrogen binding to sheep uterine receptors in vitro. J Endocrinol 1972;52:299–310.

    Google Scholar 

  6. Cheng E, Yoder L, Story CD, Burroughs W. Estrogenic activity of some isoflavone derivatives. Science 1954;120:575–7.

    Google Scholar 

  7. Yamazaki I. Effects of ipriflavone on the response of uterus and thyroid to estrogen. Life Sci 1986;38:757–64.

    Google Scholar 

  8. Yamazaki I, Shino A, Shimizu Y, Tsukuda R, Shirikawa Y, Kinoshita M. Effect of ipriflavone on glucocorticoid-induced osteoporosis in rats. Life Sci 1986;38:951–8.

    Google Scholar 

  9. Yamazaki I, Shino A, Tsukuda R. Effect of ipriflavone on osteoporosis induced by ovariectomy in rats. J Bone Miner Metab 1986;3:205–10.

    Google Scholar 

  10. Shino A, Matsuo T, Tsuda M, et al. Effect of ipriflavone on bone and mineral metabolism in the streptozotocin diabetic rats. J Bone Miner Metab 1986;3:27–37.

    Google Scholar 

  11. Yoshida K, Tsukamoto T, Torii H, et al. Disposition of ipriflavone (TC-80) in rats and dogs. Radioisotopes 1985;34:618–23.

    Google Scholar 

  12. Tsuda M, Kitazaki T, Ito T, Fujita T. The effect of ipriflavone (TC-80) on bone resorption in tissue culture. J Bone Miner Res 1987;1:207–11.

    Google Scholar 

  13. Sziklai I, Ribari O. The effect of flavone treatment on human otosclerotic ossicle organ cultures. Arch Otorhinolaryngol 1985;242:67–70.

    Google Scholar 

  14. Ribari O, Sziklai I. Effect of flavonoid on PGE2-induced alterations in percentage collagen synthesis is ossicle organ cultures. Acta Otolaryngol 1987;103:657–60.

    Google Scholar 

  15. Caputo CB, Meadows D, Raisz LG. Failure of estrogens and androgens to inhibit bone resorption in tissue culture. Endocrinology 1976;98:1065–8.

    Google Scholar 

  16. Ousler MJ, Pyfferoen J, Osdoby P, Spelsberg T. Avian osteoclast gene responses to 17-beta-estradiol treatment. J Bone Miner Res 1991;6:S297.

    Google Scholar 

  17. Ernst M, Schmid CH, Froesch ER. Enhanced osteoblast proliferation and collagen gene expression by estradiol. Proc Natl Acad Sci USA 1988;85:2307–10.

    Google Scholar 

  18. Eriksen E, Colvard DS, Berg NJ, et al. Evidence of estrogen receptors in normal human osteoblast-like cells. Science 1988;241:84–6.

    Google Scholar 

  19. Komm BS, Terpening CM, Benz DJ, et al. Estrogen binding, receptor mRNA and biological response in osteoblastlike osteosarcoma cells. Science 1988;241:240–3.

    Google Scholar 

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Brandi, M.L. Ipriflavone influences the osteoblastic phenotype in Vitro. Osteoporosis Int 3 (Suppl 1), 226–229 (1993). https://doi.org/10.1007/BF01621914

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